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Discovery Park to host DOE Energy Frontier Research Center Competition Workshop

September 10, 2019

Discovery Park will host a workshop for Purdue faculty and staff to help shape responses to the next U.S. Department of Energy (DOE) Energy Frontier Research Centers (EFRC) competition planned for fall 2019. This free event will take place from 10 a.m. to 3 p.m. Sept. 10 in the Burton D. Morgan Center for Entrepreneurship, Room 121.

Discovery Park to host DOE Energy Frontier Research Center Competition Workshop

Summary from third neuroscience-engineering workshop

August 22, 2019

The final workshop of the summer’s Life Sciences-Engineering Workshop Series drew more than 50 researchers from Purdue Life Sciences. Six teams presented their challenge statements and approaches, and they are summarized here.

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Research spotlight, August 2019: Yang Yang

August 22, 2019

Purdue Life Sciences is debuting a new feature: monthly researcher spotlights. Yang Yang is our first feature. He is an assistant professor in the Department of Medicinal Chemistry and Molecular Pharmacology in the College of Pharmacy. His lab and office space are located on the third floor of the Hall for Discovery and Learning Research, where he is affiliated with the Purdue Institute for Integrative Neuroscience (PIIN).

Research spotlight, August 2019: Yang Yang

‘A first for cancer research’: New approach to study tumors

August 22, 2019

Current drugs to treat malignant tumors may be successful at reaching the tumor site but often fail to fully reach the cancerous cells in tumors. The problem persists because tumor models used in cancer research and produced by cell culture in laboratories are not nearly the size of the actual tumors in patients. So even when a drug appears to be effective in the tiny tumors in research labs, they may perform much differently for patients.

‘A first for cancer research’: New approach to study tumors

Funding to increase food safety awareness

August 21, 2019

Purdue University will be home to a one-of-a-kind lab with the goal of increasing awareness and developing environments for food safety around the world. The lab, which will be the first-ever Feed the Future Innovation Lab for Food Safety, is possible through a $10 million grant from the United States Agency for International Development.

Funding to increase food safety awareness

‘A first for cancer research’: New approach to study tumors

August 20, 2019

WEST LAFAYETTE, Ind. – Current drugs to treat malignant tumors may be successful at reaching the tumor site but often fail to fully reach the cancerous cells in tumors. The problem persists because tumor models used in cancer research and produced by cell culture in laboratories are not nearly the size of the actual tumors in patients. So even when a drug appears to be effective in the tiny tumors in research labs, they may perform much differently for patients.

‘A first for cancer research’: New approach to study tumors

A nomogram based on 9-lncRNAs signature for improving prognostic prediction of clear cell renal cell carcinoma.

August 20, 2019

Abnormal expressions of long noncoding RNAs (lncRNAs) are very common in clear cell renal cell carcinoma (ccRCC), and some of these have been reported to be highly correlated with prognosis of ccRCC patients. "edgeR" AND "DEseq" R packages were used to explore differentially expressed genes (DEGs) between normal and tumor tissues of ccRCC samples from The Cancer Genome Atlas (TCGA). Univariable Cox survival analysis, robust likelihood-based survival model and multivariable Cox regression analysis were used to identify prognostic lncRNAs and construct lncRNAs signature. Finally, a graphic nomogram based on the lncRNAs signature was developed to predict 1-, 3- and 5-year survival probability of ccRCC patients by using rms R package.

A nomogram based on 9-lncRNAs signature for improving prognostic prediction of clear cell renal cell carcinoma.

BACTERIAL TRICK MAY LEAD TO ANTIBIOTICS WITHOUT SIDE EFFECTS

August 20, 2019

Although we may think of bacteria as disease-causing microorganisms, there are about as many bacteria in your body as human cells. And nearly all are helpful—they are nearly as essential for human survival as air, food, and water. Which is why a more selective antibiotic would be important. Current drugs kill any type of bacteria, including the helpful bacteria in our intestines that help us digest our food. When we take current antibiotics, it can cause digestive distress, and even worse outcomes. The discovery of the method the bacterium that causes Legionnaires’ uses to invade cells itself provides a path for treatment of the relatively rare disease, which affects fewer than 20,000 people per year in the United States. But the implications of the discovery go well beyond Legionnaires’.

BACTERIAL TRICK MAY LEAD TO ANTIBIOTICS WITHOUT SIDE EFFECTS

DISCOVERY PARK CENTER SEEKS DIVERSE GLOBAL SECURITY, DEFENSE SOLUTIONS

August 20, 2019

The Purdue Institute for Global Security and Defense Innovation is seeking new security and defense solutions to the global threats arising today

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Purdue-Nexus Institute Researcher Receives Prestigious Research Grant to Address Global Food Safety

August 20, 2019

Nexus researcher and Purdue Associate Professor of food science, Haley Olivier will be directing the first Feed the Future Innovation Lab for Food Safety (FSIL) in collaboration with researchers from Cornell University. The Food Safety Innovation Lab is funded by a $10 million grant awarded to Purdue from the United States Agency for International Development. The lab will aim to increase awareness of food safety measures globally, to support research on food safety issues, and to develop food safety interventions and programs for local communities and commercial stakeholders.

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