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Weldon School of Biomedical Engineering Distinguished Lecture Series

Purdue Institute for Integrative Neuroscience
November 14, 2018
9:30 AM - 10:20 AM
MJIS 1001 and via Zoom meeting at IUPUI

Description

Weldon School of Biomedical Engineering Distinguished Lecture Series presents:

"Advances in adaptive optics for microscopy and nanoscopy"

 

Martin J Booth, Ph.D.

Department of Engineering Science

University of Oxford

United Kingdom

 

Adaptive optics (AO) has been introduced into microscopes in order to overcome the problems caused by specimen-induced wavefront aberrations. This is particularly important when focusing deep into tissue where the cumulative effect of focusing through the refractive index structure of the specimen causes significant wavefront distortion.  These AO systems employ a dynamic element, such as a deformable mirror or spatial light modulator, to correct aberrations, restoring image quality. Adaptive optics has been demonstrated in a range of microscope modalities including conventional widefield microscopes as well as laser scanning systems with various applications in biomedical imaging and other areas. Adaptive microscopy has most recently been developed for super-resolution microscopes – or nanoscopes – which enable resolutions smaller than the diffraction limit of light. We will review a range of recent advances in this field, including applications in cell biology, neuroscience and other areas.  We will also discuss the future of AO in microscopy.

Contact Details

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Purdue University, West Lafayette, IN 47907 (765) 494-4600

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