Tymora Analytical Operations creates new line of products for cancer research

April 1, 2014  

WEST LAFAYETTE, Ind. - Cancer researchers in educational and commercial settings have two new tools from a Purdue Research Park-based company to help them with target detection and discovery of novel drugs to fight the disease.

Tymora Analytical Operations LLC has developed two products that could advance the testing of cancer drugs and general research objectives based on one of its technology platforms. Anton Iliuk, president and chief technology officer, said the pIMAGO product line has new applications that work with two of the most widely used techniques to detect and quantify proteins and their modifications: Western blot and ELISA.

"pIMAGO detects phosphorylation, which is the process to add a phosphate group to a protein. Phosphorylation is related to the development of several cancers and usually marks the onset of a disease," he said. "Our new line of products based on the pIMAGO platform now works with the Western blot and ELISA systems."

Iliuk said pIMAGO improves upon other methods to test pharmaceuticals in three ways: safety, cost-effectiveness and efficacy.

"pIMAGO uses no radioactive materials, so researchers are not exposed to unsafe conditions. pIMAGO is more cost-effective because researchers do not have to purchase multiple antibodies for each protein," he said. "It also is more effective in studies because it allows for sensitive universal detection of phosphorylation on any protein from any organism."

Tymora Analytical Operations commercializes work by W. Andy Tao, associate professor in Purdue's Department of Biochemistry. Company officials will attend the American Association for Cancer Research's 2014 annual meeting, April 5-9, in Booth 315 at the San Diego Convention Center.

Development of the pIMAGO product line was funded by an SBIR Phase II grant from the National Science Foundation and an SBIR Phase I grant from the National Institutes of Health.

About Tymora Analytical Operations LLC

Tymora Analytical Operations provides novel research products and reagents to Research and Development (R&D) organizations within the life sciences market. Tymora has developed a set of highly effective nanotechnologies for the analysis of protein phosphorylation that relates to the onset of numerous diseases, most notably cancer. Tymora's flagship products, PolyMAC and pIMAGO, greatly enhance an organization's ability to discover and develop new therapies that combat disease.

About Purdue Research Park

The Purdue Research Park has the largest university-affiliated business incubation complex in the country in four locations across Indiana. The parks are home to nearly 240 companies that employ more than 4,200 people and are located in West Lafayette, Merrillville, Indianapolis and New Albany. 

Purdue Research Park contact: Steve Martin, 765-588-3342, sgmartin@prf.org 

Source: Anton Iliuk, 765-490-6834, anton.iliuk@tymora-analytical.com

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