Julia Chester

Degree: Ph.D. Oregon Health and Science University, 1998

Research Interests:

My research program focuses on the study of genetic, environmental, and neurobiological factors that influence development of major mental diseases such as addiction, anxiety disorders, and schizophrenia.

Recent Publications:

Barrenha, G.D., Coon L.E., Chester, J.A. (2011). Effects of alcohol on the acquisition and expression of fear potentiated startle in mouse lines selectively bred for high and low alcohol preference. Psychopharmacology, 218(1), 191-201. Epub 2011 Apr 13.

Barrenha, G.D. & Chester, J.A. (2012). Effects of cross-fostering on alcohol preference and correlated responses to selection in high- and low-alcohol preferring mice. Alcoholism: Clinical and Experimental Research, 36(12), 2065-73. Epub 2012 May 16.

Powers*, M.S., Broderick, H., Drenan*, R.M., Chester*, J.A. (2013).  Nicotinic Acetylcholine Receptors Containing α6 Subunits Modulate Alcohol Reward Behaviors. Genes, Brain and Behavior, 12(5), 543-53. Epub 2013 May 7.

Han*, C., Salyer, A.E., Kim, E.H., Jiang, X., Jarrard, R.E., Powers, M.S., Kirchhoff, A.M., Salvador, T.K., Chester, J.A., Hockerman, G.H., Colby*, D.A (2013).  Evaluation of difluoromethyl ketones as agonists of the -amino butyric acid type B (GABAB) receptor. Journal of Medicinal Chemistry,56(6), 2456-65, Epub 2013 Mar 6.

Chester*, J.A., Kirchhoff, A. M., Barrenha, G.D. (2013). Relation between corticosterone and fear-related behavior in mice selectively bred for high or low alcohol preference.  Addiction Biology, Epub 2013 Jan 21.

Han*, B., Wright, R., Kirchhoff, A.M., Chester, J.A., Cooper, B.R., Davisson, V.J., Barker*, E.L (2013). Quantitative LC-MS/MS analysis of arachidonoyl amino acids in mouse brain with treatment of FAAH inhibitor. Analytical Biochemistry432(2), 74-81. Epub 2012 Oct 5.

Yong*, W., Spence, J.P., Eskay, R. Fitz, S.D., Damadzic, R., Lai, D., Foroud, T., Carr, L.G., Shekhar, A., Chester, J.A., Heilig, M., Liang*, T. (2014) Alcohol-preferring rats show decreased corticotropin-releasing hormone 2 receptor expression and respond differently to restraint stress compared to -nonpreferring rats. Alcoholism: Clinical and Experimental Research, 38(5): 1275-83. Epub 2014 Mar 10.

Huang*, M.C, Schwandt, M.L., Chester, J.A., Kirchhoff, A.M., Kao, C. Liang, T., Tapocik, J.D., Ramchandani, V.A., George, D.T., Hodgkinson, C.A., Goldman, D., Heilig*, M. (2014) FKBP5 moderates alcohol withdrawal severity: Human genetic association and functional validation in knockout mice.Neuropsychopharmacology, 39(8): 2029-38. Epub 2014 Mar 7.

Powers*, M.S., Chester*, J.A. (2014). Effects of stress, acute alcohol treatment, or both on prepulse inhibition in high- and low- alcohol preferring mice. Alcohol, 48(2): 113-22. Epub 2014 Jan 8.

Powers*, M.S., Breit, K.R., & Chester*, J.A. (2015). Genetic versus pharmacological assessment of the role of cannabinoid type 2 receptors in alcohol reward-related behaviors..  Alcoholism: Clinical and Experimental Research, 39(12): 2438-46.

Helms*, C.M., Bell, R.L., Bennett, A.J., Davies, D.L., Chester, J.A., Kosten, T.A., Leeman, R.F., Panicker, S., Platt, D.M., Weiner, J.L., & Edwards*, S. (2015). The importance of animals in advancing research on alcohol use disorders.  Alcoholism: Clinical and Experimental Research, 39(4): 575-8.  

Qiu*, B., Luczak, S. E., Wall, T. L., Kirchhoff , A. M., Xu, Y., Eng, M. Y., Stewart, R., Shou, W., Boehm II, S. L.,  Chester, J. A., Yong, W., & Liang*, T. (2016).  FKBP5 gene affects alcohol drinking in knockout mice and is implicated in alcohol drinking in humans.  International Journal of Molecular Sciences, 17(8): pii: E1271.

Breit*, K. R., & Chester*, J. A. (2016).  Effects of chronic stress on alcohol reward- and anxiety-related behavior in high- and low-alcohol preferring mice.  Alcoholism: Clinical and Experimental Research, 39(12): 2438-46.

Chester*, J. A., & Weera, M. M. (2017).  Genetic correlation between alcohol preference and conditioned fear: Exploring a functional relationship.  Alcohol, 58: 127-137. Published in a Special Issue on “Mouse Genetic Models of Alcohol and Stress-Alcohol Interactions.”

Julia Chester

Associate Professor, Behavioral Neuroscience

Mailing Address:
Department of Psychological Sciences
Purdue University
703 Third Street
West Lafayette, IN 47907-2081 USA

Campus Address:
Psychological Sciences, Room 3162

E-mail: jcheste@purdue.edu
Telephone: (765) 494-6863

Psychological Sciences, 703 Third Street, West Lafayette, IN 47907, (765) 494-6061 FAX: (765) 496-1264

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