Wayne Campbell

Educational Background

  • B.S., Nutritional Sciences at University of Delaware in 1984
  • M.S., Nutritional Sciences at University of Maryland in 1987
  • Ph.D, Nutritional Sciences at Tufts University in 1993
  • Post-Doc., Nutrition/Exercise/Aging at The Pennsylvania State University in 1997

Awards & Honors

  • Research Excellence Award, Center on Aging and the Life Course, Purdue University, 2016
  • University Scholar from Purdue University, 2008 - 2013
  • Career Research Achievement Award from College of Health and Human Sciences, Purdue University, 2012
  • Undergraduate Honors Mentor Award, College of Consumer and Family Sciences from Purdue University, 2009
  • Presidential Citation for Outstanding Achievement from University of Delaware, 2000

Activities & Memberships

  • Member, Advisor Council on Nutrition and Healthy Food Choices, Foundation for Food and Agriculture Research (foundationfar.org), 2016 - Present
  • Member, 2018 Physical Activity Guidelines Advisory Committee, United States Department of Health and Human Services, 2016 - Present
  • Member, 2015 Dietary Guidelines for Americans Committee from USDA and HHS, 2013 - 2015
  • Clinical Research Center and Bionutrition Services Core (Director), Purdue University (from NIH-supported Clinical and Translational Sciences Institute), 2008 - 2015
  • Member and Fellow of the Obesity Society, 2006 - Present
  • Member of the American Society for Nutrition, 2006 - Present
  • Scientific review panelist for USDA, NIH, NASA, NSBRI, VSARIEM, and FAA, 2000-2014


Our research interests include human nutrition and exercise studies on protein, carbohydrate and energy metabolism, dietary protein and energy requirements, body composition, obesity, weight loss, muscle strength, and muscle function with special emphasis on aging. We are also interested in how nutrition, exercise, and aging impact appetite and ingestive behaviors. Our research suggests that older people who habitually consume the Recommended Dietary Allowance for protein experience subtle declines in skeletel muscle size. Thus we seek to find the optimal protein intake for older and elderly people to consume. Our research also focuses on how protein metabolism, body composition, and glucose metabolism change in older people with changes in protein intake, body weight, and exercise (especially strength training). We are also interested in evaluating the effectiveness of compounds that are promoted to have ergogenic properties (e.g. whey protein). 

Our research includes the use of traditional metabolic balance techniques (with strict dietary control possible in a metabolic research kitchen), stable isotope infusion techniques (to measure in vivo amino acid turnover and incorporation into muscle tissues), body composition (plethysmography, dual x-ray absorptiometry, deuterium oxide dilution, magnetic resonance imaging), the muscle biopsy technique (to obtain small samples of human skeletal muscle), and indirect calorimetry (to measure resting and exercise energy expenditure). We also highly value collaboration within and outside of Purdue to expand our interests, expertise, and research capabilities.

Discovery Publications

  • O'Connor, L.E., Kim, J.E., Campbell, W.W. (2016) Total red meat intake of ≥0.5 servings/d does not negatively influence cardiovascular disease risk factors: a systematically searched meta-analysis of randomized controlled trials.  Am J Clin Nutr. 2016 Nov 23, pii: ajcn 142521 [Epub ahead of print] PMID: 27881394.
  • Kim, J.E., Ferruzzi, M.G., Campbell, W.W. (2016) Egg consumption increased vitamin E absorption from co-consumed raw mixed vegetables in healthy young men.  J Nutr.  146(11):2199-2205. PMID: 27655756.
  • Sayer, R.D., Tamer, G.G. Jr., Chen, N., Tregellas, J.R., Cornier, M.A., Kareken, D.A., Talavage, T.M., McCrory, M.A., Campbell, W.W. (2016) Reproducibility assessment of brain responses to visual food stimuli in adults with overweight and obesity.  Obesity (Silver Spring). 24(10):2057-63. doi: 10.1002/oby.21603.  PMID: 27542906.
  • Rafii, M., Chapman, K., Elango, R., Campbell, W.W., Ball, R.O., Pencharz, P.A.B., Courtney-Martin, G. (2016) Dietary protein requirement of men >65 years old determined by the indicator amino acid oxidation technique is higher than the current estimated average requirement. J Nutr. 2016 Mar 9. [Epub ahead of print].  PMID: 26962173.
  • O'Connor, L.E., Campbell, W.W. (2016) A novel fiber composite ingredient incorporated into a beverage and bar blunts postprandial serum glucose and insulin responses: a randomized controlled trial.  Nutr Res. 36(3):2530261.  PMID: 26923512.
  • Kim, J.E., O'Connor, L.E., Sands, L.P., Slebodnik, M.B., Campbell, W.W. (2016) Effects of dietary protein intake on body composition changes after weight loss in older adults: a systematic review and meta-analysis. Nutr Rev. 74(3):210-224.  PMID: 26883880.
  • Zhou, J., Kim, J.E., Armstrong, C.L., Chen, N., Campbell, W.W. (2016) Higher-protein diets improve indexes of sleep in energy-restricted overweight and obese adults: results from 2 randomized controlled trials.  Am J Clin Nutr. 103(3):766-774.  PMID: 26864362.
  • Li, J., Armstrong, C.L.H., Campbell, W.W. (2016) Effects of dietary protein source and quantity during weight loss on appetite, energy expenditure, and cardio-metabolic responses.  Nutritients. 8(2):63.  PMID 26821042.
  • Sayer, R.D., Amankwaah, A.F., Tamer, G.G., Chen, N., Wright, A.J., Tregellas, J.R., Cornier, M.A., Kareken, D.A., Talavage, T.M., McCrory, M.A., Campbell, W.W. (2016) Effects of Dietary Protein and Fiber at Breakfast on Appetite, ad Libitum Energy Intake at Lunch, and Neural Responses to Visual Food Stimuli in Overweight Adults. Nutrients. 8(1):pii: E21.  PMID: 26742068.
  • Wright, C.S., Craddock, A., Weinheimber-Haus, E.M., Lim, E., Conley, T.B., Janle, E.M., Campbell, W.W. (2016) Thyroid status, insulin sensitivity and glucose tolerance in overweight and obese adults before and after 36 weeks of whey protein supplementation and exercise training.  Endocr Res. 41(2):103-9.  PMID: 26727029.
  • Wright, C.S., Weinheimer-Haus, E.M., Fleet, J.C., Peacock, M., Campbell, W.W. (2015) The apparent relation between plasma 25-hydroxyvitamin D and insulin resistance is largely attributable to central adiposity in overweight and obese adults.  J Nutr. 145(12):2683-2689.  PMID: 26446485.
  • Campbell, W.W., Kim, J.E., Amankwaah, A.F., Gordon, S.L., Weinheimer-Haus, E.M. (2015) Higher Total protein intake and change in total protein intake affect body composition but not metabolic syndrome indexes in middle-aged overweight and obese adults who performed resistance and aeobic exercise for 36 weeks. J Nutr. 145(9):2076-83. PMID: 26246322.
  • Sayer, R.D., Wright, A.J., Chen, N., Campbell, W.W. (2015) Dietary Approaches to Stop Hypertension diet retains effectiveness to reduce blood pressure when lean pork is substituted for chicken and fish as the predominant source of protein.  Am J Clin Nutr. 102(2):302-308. PMID: 26063693.
  • Kim, J.E., Gordon, S.L., Ferruzzi, M.G., Campbell, W.W. (2015) Effects of egg consumption on carotenoid absorption from co-consumed, raw vegetables. Am J Clin Nutr. 102(1):75-83. PMID: 26016861.
  • Rafii, M., Chapman, K., Owens, J., Elango, R., Campbell, W.W., Ball, R.O., Pencharz, P.B., Courtney-Martin, G. (2015) Dietary Protein Requirement of Female Adults >65 Years Determined by the Indicator Amino Acid Oxidation Technique Is Higher Than Current Recommendations. J Nutr. 145:18-24.  PMID: 25320185. 
  • Tang, M., O'Connor, L.E., Campbell, W.W. (2014) Diet-induced weight loss: the effect of dietary protein on bone. J Acad Nutr Diet. 114(1): 72-85.  PMID 24183993.
  • Tang, M., McCabe, G.P., Elango, R., Pencharz, P.B., Fall, R.O., Campbell, W.W. (2014) Assessment of protein requirement in octogenarian women with use of the indicator amino acid oxidation techniquei. Am J Clin Nutr. 99(4):891-898. PMID 24429540.
  • Tang, M., Leidy, J.H., Campbell, W.W. (2013) Regional, but not total, body composition changes in overweight and obese adults consuming a higher protein, energy-restricted diet are sex specific. Nutr Res. 33(8):629-635. PMID: 23890352.
  • Tang, M., Armstrong, C.L.H., Leidy, H.J., Campbell, W.W. (2013) Normal vs. high-protein weight loss diets in men: effects on body composition and indices of metabolic syndrome. Obesity. 21(3):E204-E210. PMID: 23592676.
  • Goltz, S.R., Sapper, T.N., Failla, M.L., Campbell, W.W., Ferruzzi, M.G. (2013) Carotenoid bioavailability from raw vegetables and a moderate amount of oil in human subjects is greatest when the majority of daily vegetables are consumed at one meal. Nutr Res. 33(5):358-366. (Epub 2013 Apr 23). PMID: 23684437.
  • Goltz, S.R., Campbell, W.W., Chitchumroonchokchai, C., Failla, M.L., and Ferruzzi, M.G. (2012) Meal triacylglycerol profile modulates postprandial absorption of carotenoids in humans. Mol Nutr Food Res. 6:866-877. PMID 22707262.
  • Weinheimer, E.M., Conley, T.B., Kobza, V.M., Sands, L.P., Lim, E., and Campbell, W.W. (2012) Whey protein supplementation does not affect exercise training-induced changes in body composition and indices of metabolic syndrome in middle-aged overweight and obese adults. J Nutr. 8:1532-1539. PMID 22718030.
  • Conley, T.B., McCabe, G.P., Lim, E., Yarasheski, K.E., Johnson, C.A., and Campbell, W.W. (2012) Age and sex affect protein metabolism at protein intakes that span the range of adequacy: comparison of leucine kinetics and nitrogen balance data. J Nutr Biochem. 2012 Jul 26 [Epub ahead of print] PMID 22841544.
  • Leidy HJ, Tang M, Armstrong CLH, Martin CB, and Campbell WW. (2011) The effects of consuming frequent, higher protein meals on appetite and satiety during weight loss in overweight/obese men. Obesity. 19(4):818-824.
  • Campbell, W.W. and Tang, M. (2010) Protein intake, weight loss, and bone mineral density in postmenopausal women. J Gerontol A Biol Scie Med Sci. 65(10):1115-22.
  • Thalacker-Mercer, A.E., Fleet, J.C., Craig, B.A., and Campbell, W.W. (2010) The skeletal muscle transcript profile reflects accommodative responses to inadequate protein intake in younger and older males. J Nutr Biochem. 21(11):1076-82.
  • Weinheimer, E.M., Sands, L.P., and Campbell, W.W. (2010) A systematic review of the separate and combined effects of energy restriction and exercise on fat-free mass in middle-aged and older adults: Implications for sarcopenic obesity. Nutr Rev. 68(7):375-388.
  • Laan, D.J., Leidy, H.J., Lim, E., and Campbell, W.W. (2010) Effects and reproducibility of aerobic and resistance exercise on appetite and energy intake in young, physically active adults. Appl Physiol Nutr Metab. 35(6):842-847.
  • Leidy HJ, Armstrong CLH, Tang M, Mattes RD, and Campbell WW. (2010) The influence of higher protein intake and greater eating frequency on appetite control in overweight and obese men. Obesity. 18(9):1725-32.

Books, Chapters & Monograph Publications

  • Li, J., O'Connor, Zhou, J., Cambell, W.W. (2014) Exercise patterns, ingestive behaviors, and energy balance. Physiolo Behav. 134:70-75. PMID 247472277.
  • Campbell, W.W., Weinheimer, E.M., Tang, M. (2014) Protein Metabolism and Requirements. In: Geriatric Nutrition: The Health Professional's Handbook, 4th edition. Ronni Chernoff Ed(s). Ch.2 Jones and Bartlett Learning, Burlington, MA/USA.
  • Zhou, J., Li, J., Campbell, W.W. (2013) Vegetarian Athletes. In: Nutrition and Enhanced Sports Performance: Muscle Building, Endurance, and Strength. Bagchi, D., Nair, S., Sen, C.K Ed(s). Ch.10. Pp.Pages. Academic Press (Elsevier), Waltham, MA. 
  • Volpi, E., Campbell, W.W., Dwyer, J.T., Johnson, M.A., Jensen, G.L., Morley, J.E., and Wolfe R.R. (2012) Is the optimal level of protein intake for older adults greater than the recommended dietary allowance?. J Gerontol A Biol Sci Med Sci. 2012 Nov 26 [Epub ahead of print].
  • Leidy, H.J. and Campbell, W.W. (2011) The effect of eating frequency on appetite control and food intake brief synopsis of controlled feeding studies. J Nutr. 141:154-157. PMID 21123467.
  • McCrory, M.A. and Campbell, W.W. (2011) Effects of eating frequency, snacking and breakfast skipping on energy regulation: symposium overview. J Nutr. 141:144-147. PMID 21123468.
  • Paddon-Jones, D., Short, K.R., and Campbell, W.W. (2008) Role of dietary protein in the sarcopenia of aging. Am J Clin Nutr. 87:1562S-1566S.
  • Thalacker-Mercer, A.E. and Campbell, W.W. (2008) Dietary protein intake affects albumin fractional synthesis rate in younger and older adults equally. Nutr Rev. 66(2):91-05.
  • Campbell, W.W. and Leidy, H.J. (2007) Dietary protein and resistance training effects on muscle and body composition in older persons. J Am Coll Nutr. 26(6):696S-703S.
  • Campbell, W.W. (2007) Synergistic use of higher-protein diets or nutritional supplements with resistance training to counter sarcopenia. Nutrition Reviews. 65(9):416-422.
  • Campbell, W.W., Carnell, N.S., and Thalacker, A.E. (2006) Protein metabolism and requirements. In: Geriatric Nutrition: The Health Professional's Handbook, 3rd Edition. Ronni Chernoff Ed(s). Ch.2. Jones and Bartlett Publishers, Inc., Sudbury, Massachusetts.
  • Castellanos, V.H., Litchford, M., and Campbell, W.W. (2006) Modular protein supplements and their application to long term care. Nutrition in Clinical Practice. 21:484-504.
  • Venderley, A.M. and Campbell, W.W. (2006) Vegetarian diets: nutritional considerations for athletes. Sports Medicine. 36(4):293-305.
  • Campbell, W.W. (2006) Exercise. In: Present Knowledge in Nutrition, 9th edition. Bowman, B.A. and Russell, R.M Ed(s). International Life Sciences Institute Press, Washington, D.C..


NUTR 48800 Topics in Nutrition, Fitness, and Health: This course is designed to provide juniors and seniors in the nutrition, fitness, and health curriculum with a review of the current literature as it relates to their major. Specific information from previous courses in separate disciplines will be integrated to study the interrelationships between nutrition and exercise and their impact on physical performance and health. Concepts combining nutritional sciences and exercise physiology will be presented, and controversies in the current literature will be discussed.

Wayne Campbell

Faculty Associate:
  Center on Aging and the Life Course

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Phone: 765.494.8236
Fax: 765.494.0674
E-Mail: campbellw@purdue.edu

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