Carlos Pérez-Torres, Ph.D.

Research Interests / Training Areas

  • Magnetic Resonance Imaging (MRI)
    -Diffusion, Perfusion, and Magnetization Transfer

  • Radiation Biology
    -Radiation Necrosis and Radiation-Induced Cognitive Impairment

  • Brain Tumors
    -Imaging characteristics and response to therapy

Biography

Dr. Carlos Pérez-Torres is an Assistant Professor of Radiological Health Sciences within the School of Health Sciences at Purdue University. Dr. Pérez-Torres obtained his B.S. degree from Worcester Polytechnic Institute in Biology and Biotechnology in 2007 and his PhD degree from Baylor College of Medicine in Translational Biology and Molecular Medicine in 2012. As a postdoctoral researcher in Washington University in Saint Louis, Dr. Pérez-Torres helped validate and characterize a mouse model of Radiation Necrosis, a late-onset side-effect of radiation therapy that mimics a tumor on standard anatomical MRI. As a faculty at Purdue University, Dr. Pérez-Torres continues to focus on how radiation treatment affects the normal brain to develop better diagnostic MRI tools (is it tumor or just a treatment side effect?) and to potentially improve radiation therapy of brain tumors.

Recent/Representative Publications

Perez-Torres CJ, Yuan L, Schmidt RE, Rich KM, Drzymala RE, Hallahan DE, Ackerman JJH, and Garbow JR. “Specificity of Vascular Endothelial Growth Factor Treatment for Radiation Necrosis”. Radiotherapy and Oncology. Accepted Manuscript 

Jiang X, Yuan L, Engelbach  JA, Cates J, Perez-Torres CJ, Gao F, Thotala D, Drzymala RE, Schmidt RE, Rich KM, Hallahan DE, Ackerman JJH, and Garbow JR. “A Gamma-Knife-Enabled Mouse Model of Cerebral Single-Hemisphere Delayed Radiation Necrosis”. PLOS One. Accepted Manuscript.

Beeman SC, Shui YB, Perez-Torres C, Engelbach J, Ackerman JJH, and Garbow, JR. “O2-Sensitive-Sensitive MRI Distinguishes Brain Tumor vs. Radiation Necrosis in Murine Models”. Magnetic Resonance in Medicine. In press

Perez-Torres CJ, Yuan L, Schmidt RE, Rich KM, Ackerman JJH, Garbow JR. “Perilesional edema in radiation necrosis reflects axonal degeneration”. Radiation Oncology 2015 Jan 31;10(1):33. PMID: 25636531 PMCID: PMC4331301

Perez-Torres CJ, Engelbach JA, Cates J, Thotala DK, Yuan L, Schmidt RE, Rich KM, Drzymala RE, Ackerman JJH, and Garbow JR. “Towards Distinguishing Recurrent Tumor from Radiation Necrosis: DWI and MTC in a Gamma Knife® Irradiated Mouse Glioma Model”. International Journal of Radiation Oncology*Biology*Physics 2014 Oct 1; 90(2):446–453. PMID: 25104071 PMCID: PMC4307945.

Jiang X, Perez-Torres CJ, Thotala D, Engelbach  JA, Yuan L, Cates J, Gao F,  Drzymala RE, Hallahan DE, Rich KM, Schmidt RE, Ackerman JJH, and Garbow JR. “GSK-3β inhibition protects against radiation necrosis in mouse brain”, International Journal of Radiation Oncology*Biology*Physics 2014 Jul 15;89(4):714–721. PMID: 24969790 PMCID: PMC4307920.

For full publication history see: http://www.ncbi.nlm.nih.gov/myncbi/browse/collection/47396141/?sort=date&direction=descending

Carlos Perez-Torres
Assistant Professor

Phone: 765-494-2974
Fax: 765-496-1377
E-mail: cperezto@purdue.edu

Purdue University, School of Health Sciences, 550 Stadium Mall Drive, West Lafayette, IN 47907, (765) 494-1419, Fax: (765) 496-1377

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