Kevin Solomon

Kevin Solomon Profile Picture

Assistant Professor of Agricultural & Biological Engineering
Ph.D., Chemical Engineering, MIT (2012) M.S., Chemical Engineering Practice (2008) B. Eng, Chemical Engineering & Bioengineering, McMaster University (2006)

Contact Info:

Training Group(s):
Biotechnology

Active Mentor - currently hosting PULSe students for laboratory rotations and recruiting PULSe students into the laboratory; serves on preliminary exam committees

Current Research Interests:

Prof. Solomon’s research focuses on developing more efficient microbial chemical factories that sustainably produce fuels, medicines and advanced materials. Central to these factories are genes which sometimes interact with each other and the environment in unanticipated and adverse ways. We employ systems level -omics approaches to rapidly identify these interactions, and program molecular solutions with synthetic biology to overcome these effects for superior performance.

Selected Publications:

C Hooker, E Hillman, J Overton, A Ortiz-Velez, M Schacht, A Hunnicutt, N Mosier, KV Solomon*, Hydrolysis of untreated lignocellulosic feedstock is independent of S-lignin composition in newly classified anaerobic fungal isolate, Piromyces sp. UH3-1, Biotechnology for Biofuels, 11:293 (2018).

CH Haitjema, SP Gilmore, JK Henske, KV Solomon, R de Groot, A Kuo, S Mondo, AA Salamov, K LaButti, Z Zhao, J Chinquy, K Barry, HM Brewer, SO Purvine, AT Wright, B Boxma, T van Alen, JHP Hackstein, SE Baker, K Barry, IV Grigoriev, MA O’Malley*, A Parts List for Fungal Cellulosomes Revealed by Comparative Genomics, Nature Microbiology, 2:17087, (2017).

KV Solomon, E Ovadia, F Yu, W Mizunashi, MA O’Malley*. Mitochondrial targeting increases specific activity of a heterologous valine assimilation pathway in Saccharomyces cerevisiae, Metabolic Engineering Communications, 3:68-75, (2016)

KV Solomon, CH Haitjema, JK Henske, SP Gilmore, D Borges-Rivera, A Lipzen, HM Brewer, SO Purvine, AT Wright, MK Theodorou, IV Grigoriev, A Regev, DA Thompson, MA O’Malley*. Early-branching gut fungi possess a large, comprehensive array of biomass degrading enzymes. Science, 351 (6278): 1192 - 1195, (2016)

KV Solomon, TM Sanders, KLJ Prather*. A dynamic metabolite valve for the control of central carbon metabolism. Metabolic Engineering, 14(6): 661-671, (2012).

CH Haitjema, KV Solomon, JK Henske, MK Theodorou, MA O’Malley. Anaerobic Gut Fungi: Advances in Isolation, Culture, and Cellulolytic Enzyme Discovery for Biofuel Production. Biotechnology and Bioengineering, 8(111): 1471-1482, (2014).

KV Solomon, CH Haitjema, DA Thompson, MA O’Malley. Extracting data from the muck: deriving biological insight from complex microbial communities and non-model organisms with next generation sequencing. Current Opinion in Biotechnology, 28:103-110, (2014).

KV Solomon, TS Moon, B Ma, TM Sanders, KLJ Prather.Tuning primary metabolism for heterologous productivity. ACS Synthetic Biology, 2(3):126-135, (2013).

CH Martin, DR Nielsen, KV Solomon & KLJ Prather. Synthetic Metabolism: Engineering Biology at the Protein and Pathway Scales. Chemistry & Biology, 16: 277-286, (2009).

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