Lauren Ann Metskas
Assistant Professor
Ph.D., Yale University
metskas@purdue.edu
765-494-4909
Office: HOCK 231
Metskas Lab
Biomolecular Structure and Biophysics
Microbiology, Immunology and Infectious Diseases
Chemical Biology
Active Mentor - currently hosting PULSe students for laboratory rotations and recruiting PULSe students into the laboratory; serves on preliminary exam committees
Current Research Interests:
Our group’s research focuses around functional protein ultrastructures, such as protein lattices involved in pathogen-host interaction. We use a mixture of structural biology, biophysics and chemistry to study these systems and design new experimental methods.Selected Publications:
Metskas, L.A., Ortega, D., Oltrogge, L.M., Blikstad, C., Laughlin, T., Savage, D.F., Jensen, G.J. (2022) Rubisco Forms a Lattice in Alpha-Carboxysomes. Biorxiv [preprint], January 25, 2022. Available from: https://doi.org/10.1101/2022.01.24.477598.
Metskas LA, Briggs JAG. Fluorescence-Based Detection of Membrane Fusion State on a Cryo-EM Grid using Correlated Cryo-Fluorescence and Cryo-Electron Microscopy. Microsc Microanal. 2019 Aug; 25(4):942-949.
Metskas LA, Rhoades E. Single-Molecule FRET of Intrinsically Disordered Proteins. Annu Rev Phys Chem. 2020 Apr 20; 71:391-414.
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