Daisuke Kihara

Active Mentor - currently hosting PULSe students for laboratory rotations and recruiting PULSe students into the laboratory; serves on preliminary exam committees

Current Research Interests:

Protein bioinformatics. We develop and apply bioinformatics tools for protein tertiary structure modeling, protein docking modeling, protein function prediction, structure-modeling for cryo-electron microscopy density maps, virtual drug screening. We design algorithms and apply machine learning methods.

Selected Publications:

Genki Terashi & Daisuke Kihara, De novo main-chain modeling for EM maps using MAINMAST. Nature Communications, 9: 1618 (2018)

Lenna X. Peterson, Yoichiro Togawa, Juan Esquivel-Rodriguez, Genki Terashi, Charles Christoffer, Amitava Roy, Wooong-Hee Shin, & Daisuke Kihara, Modeling the assembly order of multimeric heteroprotein complexes. PLoS Comput. Biol., 14:e1005937 (2018)

Ishita K. Khan, Mansurul Bhuiyan, & Daisuke Kihara, DextMP: deep dive into text for predicting moonlighting proteins. Bioinformatics, 33: i83-i91 (2017)

Lenna X. Peterson, Amitava Roy, Charles Christoffer, Genki Terashi, & Daisuke Kihara , Modeling disordered protein interactions from biophysical principles. PLoS Computational Biol., 13: e1005485, (2017)

Lyman Monroe, Genki Terashi, & Daisuke Kihara, Variability of protein structure models from electron microscopy. Structure, 25: 592-602 (2017)