{"id":952,"date":"2022-09-12T20:09:58","date_gmt":"2022-09-12T20:09:58","guid":{"rendered":"https:\/\/www.purdue.edu\/fnr\/sites\/sepulveda\/?page_id=952"},"modified":"2022-12-06T19:19:16","modified_gmt":"2022-12-06T19:19:16","slug":"projects","status":"publish","type":"page","link":"https:\/\/www.purdue.edu\/fnr\/sites\/sepulveda\/projects\/","title":{"rendered":"Projects"},"content":{"rendered":"
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Current Projects<\/strong><\/h5>\n<\/div>\n<\/div><\/div><\/div><\/div>
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Biosolids as a source of PFAS to Wetlands<\/strong><\/a><\/p>\n<\/div>\n<\/div><\/div><\/div>

\"Crayfish<\/div><\/div><\/div>
<\/div>
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Deformities, Erosions, Lesions, and
\nTumors (DELTs)<\/strong><\/a><\/p>\n<\/div>\n<\/div><\/div><\/div>

\"Spotfin<\/div><\/div><\/div>
<\/div>
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Development of Chemical Resistance<\/strong><\/a><\/p>\n<\/div>\n<\/div><\/div><\/div>

\"lamprey\"<\/div><\/div><\/div>
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Effects of PFAS on Lipid Metabolism<\/strong><\/a><\/p>\n<\/div>\n<\/div><\/div><\/div>

\"Xenopus<\/div><\/div><\/div>
<\/div>
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Florida Pompano and Low
Salinity<\/strong><\/a><\/p>\n<\/div>\n<\/div><\/div><\/div>

\"pompano<\/div><\/div><\/div>
<\/div>
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Modeling of PFAS Mixture
\nToxicity<\/strong><\/a><\/p>\n<\/div>\n<\/div><\/div><\/div>

\"Modeling<\/div><\/div><\/div>
<\/div><\/div>
<\/div>
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Neurotoxicity of PFAS<\/strong><\/a><\/p>\n<\/div>\n<\/div><\/div><\/div>

\"neurotoxicity\"<\/div><\/div><\/div>
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PFAS and Hypoxia in The Great Lakes<\/strong><\/a><\/p>\n<\/div>\n<\/div><\/div><\/div>

\"PFAS<\/div><\/div><\/div>
<\/div><\/div>
<\/div>
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PFAS Toxicity to Amphibians<\/strong><\/a><\/p>\n<\/div>\n<\/div><\/div><\/div>

\"Amphibians,<\/div><\/div><\/div>
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Rana Genome Sequencing<\/strong><\/a><\/p>\n<\/div>\n<\/div><\/div><\/div>

\"Graph,<\/div><\/div><\/div>
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Past Projects<\/strong><\/h5>\n<\/div>\n<\/div><\/div><\/div><\/div>
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Digital Environment for Enabling Data-Driven Science (DEEDS)<\/a> <\/i><\/div>\n
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We are building a web platform that provides a full spectrum of data services, connects data to computational resources and statistical software, and tracks research workflows to link data, algorithms and results.<\/p>\n

Post-Doctoral Researcher:<\/b> Tyler Hoskins
\nFunding:<\/b> The National Science Foundation Award # 1724728
\nPI:<\/b> Ann Christine Catlin\n<\/p><\/div>\n

\"Digital<\/a><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n
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Toxicology of Nanoplastics<\/a> <\/i><\/div>\n
\n
\n
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We are evaluating the organ distribution of nanoplastics in zebrafish.
\nPhD Student:<\/b> Rui Zhang
\nFunding:<\/b> China Scholarship Council and Department of Forestry and Natural Resources, Purdue University<\/div>\n
\"Toxicology<\/a><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n
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Integrating Teleost Transcriptomes to Identify Ecologically meaningful Responses Following Oil Exposure<\/a> <\/i><\/div>\n
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Using high throughput sequencing tools, we are identifying: 1) conserved patterns of response to oil across multiple species; 2) subtle effects resulting from exposure to oil that may have implications for future fisheries management practices, and; 3) novel hypotheses regarding the effects of oil on ecologically important fish species in the Gulf of Mexico.
\nMS Student:<\/b> Maggie Wigren
\nPhD Student:<\/b> Elizabeth Allmon
\nFunding:<\/b> Gulf of Mexico Research Initiative RFP VI
\nPI:<\/b> Robert J Griffitt<\/div>\n
\"Integrating<\/a><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n
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Temperature and Sex Differentiation in Fathead Minnows<\/a> <\/i><\/div>\n
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\nWe evaluated how temperature influences sex differentiation in fathead minnows. We induced non-directional sex reversal after exposing embryos and larvae from 0 h post fertilization to 45 days post hatch to fluctuating temperatures. Expression of hsp70 cycled with temperature.

<\/p>\n

Student:<\/b> David Coulter(PhD) (was co-advised with Tomas H\u00f6\u00f6k)
\nFunding:<\/b> Electric Power Research Institute (EPRI)\n<\/p><\/div>\n

\"Temperature<\/a><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n
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Fish Diseases<\/a> <\/i><\/div>\n
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The objective of this study was to determine the prevalence of diseases (virus, bacteria, and helminths) from exotic silver and bighead carps from the Wabash River, IN.

<\/p>\n

Student:<\/b> Kensey Thurner
\nFunding:<\/b> Indiana Department of Natural Resources (IDNR)\n<\/p><\/div>\n

\"Fish<\/a><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n
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Pharmaceuticals and Personal Care Products (PPCPs)<\/a> <\/i><\/div>\n
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We quantified PPCPs at the Baca Wildlife Refuge, CO and evaluated their impact to native fish such as the Rio Grande chub. We also conducted laboratory experiments with fathead minnows and examined mechanisms of toxicity of DEET, triclocarban, cotinine, and complex mixtures.

<\/p>\n

MS Student:<\/b> Jenny Zenobio
\nFunding:<\/b> United States Fish and Wildlife Service (USFWS) and Illinois-Indiana Sea Grant\n<\/p><\/div>\n

\"Pharmaceuticals<\/a><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n
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Function of miRNAs in Daphnia pulex<\/a> <\/i><\/div>\n
\n
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We have identified and validated a set of miRNAs from D. pulex that are responsive to heavy metal exposure.

<\/p>\n

PhD Student:<\/b> Shuai Chen (co-advised by Krista Nichols)
\nFunding:<\/b> Department of Forestry and Natural Resources, Purdue University\n<\/p><\/div>\n

\"Function<\/a><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n
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Toxicology of Nanosilver<\/a> <\/i><\/div>\n
\n
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The objective of these studies was to assess the mechanism of vascular toxicity of nanosilver.

<\/p>\n

PhD Student:<\/b> Jiejun Gao
\nFunding:<\/b> China Scholarship Council and Department of Forestry and Natural Resources, Purdue University\n<\/p><\/div>\n

\"Toxicology<\/a><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n
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Epigenetic Mechanisms of Atrazine<\/a> <\/i><\/div>\n
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Using the zebrafish, we evaluated how a developmental exposure to atrazine results in later-in-life effects.

<\/p>\n

Funding:<\/b> National Institute of Environmental Health Sciences
\nPI:<\/b> Jennifer Freeman\n<\/p><\/div>\n

\"Epigenetic<\/a><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n
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Combined Effects of Abiotic Stressors and Oil Contaminants<\/a> <\/i><\/div>\n
\n
\n
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We evaluated the combined effects of extreme dissolved oxygen, temperature, salinity and oil on growth and survival of Fundulus grandis.

<\/p>\n

MS Students:<\/b> Jennifer Serafin and Christopher Klinkhammer
\nFunding:<\/b> Gulf of Mexico Research Initiative\n<\/p><\/div>\n

\"Combined<\/a><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n
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Molecular Markers of Gonadal Development and Intersex<\/a> <\/i><\/div>\n
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We developed a transgenic Japanese Medaka model for detecting estrogens and anti-estrogens in water.

<\/p>\n

PhD Student:<\/b> Ahmed Abdel-Moneim
\nFunding:<\/b> Egyptian Government and Department of Forestry and Natural Resources, Purdue University\n<\/p><\/div>\n

\"Molecular<\/a><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div><\/div><\/div><\/div><\/div>
<\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"

Current Projects Biosolids as a source of PFAS to Wetlands Deformities, Erosions, Lesions, and Tumors (DELTs) Development of Chemical Resistance<\/p>\n","protected":false},"author":55,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-952","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/www.purdue.edu\/fnr\/sites\/sepulveda\/wp-json\/wp\/v2\/pages\/952","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.purdue.edu\/fnr\/sites\/sepulveda\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.purdue.edu\/fnr\/sites\/sepulveda\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.purdue.edu\/fnr\/sites\/sepulveda\/wp-json\/wp\/v2\/users\/55"}],"replies":[{"embeddable":true,"href":"https:\/\/www.purdue.edu\/fnr\/sites\/sepulveda\/wp-json\/wp\/v2\/comments?post=952"}],"version-history":[{"count":57,"href":"https:\/\/www.purdue.edu\/fnr\/sites\/sepulveda\/wp-json\/wp\/v2\/pages\/952\/revisions"}],"predecessor-version":[{"id":1723,"href":"https:\/\/www.purdue.edu\/fnr\/sites\/sepulveda\/wp-json\/wp\/v2\/pages\/952\/revisions\/1723"}],"wp:attachment":[{"href":"https:\/\/www.purdue.edu\/fnr\/sites\/sepulveda\/wp-json\/wp\/v2\/media?parent=952"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}