{"id":637,"date":"2021-12-01T19:17:50","date_gmt":"2021-12-01T19:17:50","guid":{"rendered":"https:\/\/www.purdue.edu\/fnr\/hoverman\/?page_id=637"},"modified":"2025-07-01T18:15:08","modified_gmt":"2025-07-01T18:15:08","slug":"acute-toxicity","status":"publish","type":"page","link":"https:\/\/www.purdue.edu\/fnr\/hoverman\/acute-toxicity\/","title":{"rendered":"Acute Toxicity"},"content":{"rendered":"<div  class=\"section has-padding-bottom-small  page-layout-wide\">\n    <div class=\"container\">\n                \n\n<div class=\"wp-block-columns page-layout-columns columns is-multiline is-layout-flex wp-container-core-columns-is-layout-8f761849 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column column is-full-tablet page-layout-main is-layout-flow wp-block-column-is-layout-flow\">\n<h1 class=\"wp-block-heading\">Acute Toxicity<\/h1>\n\n\n\n<p class=\"wp-block-paragraph\">Because little is known regarding the toxicity of PFAS-free AFFF formulations, the first phase of our project was focused on acute toxicity trials (e.g.., range-finding studies, lethal concentration tests).\u00a0 These studies determined the general toxicity of the formulations and informed our selection of concentrations for our chronic exposures experiment.\u00a0 In brief, the acute toxicity trials are conducted across a broad range of concentrations of the formulations and survival was monitored daily for 48 hours.\u00a0 The data is then used to calculate the 48-hour LC10, LC50, and LC90 values.\u00a0 This data was published in collaboration with other SERDP funded group: Jones, DK, KA Quinlin, MA Wigren, YJ Choi, MS Sep\u00falveda, LS Lee, DL Haskins, GR Lotufo, A Kennedy, L May, A Harmon, T Biber, N Melby, MK Chanov, ML Hudson, PB Key, KW Chung, DW Moore, JG Suski, EF Wirth, and JT Hoverman. 2022.\u00a0<a href=\"https:\/\/pubs.acs.org\/doi\/abs\/10.1021\/acs.est.1c03776\" target=\"_blank\" rel=\"noreferrer noopener\">Acute toxicity of eight aqueous film-forming foams to 13 aquatic species<\/a>.\u00a0<em>Environmental Science &amp; Technology<\/em>. 56:6078\u20136090.<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-column column is-one-quarter-desktop is-full-tablet is-full-mobile page-layout-sidebar is-layout-flow wp-block-column-is-layout-flow\">\n<p class=\"wp-block-paragraph\"><\/p>\n<\/div>\n<\/div>\n\n    <\/div>\n<\/div>\n\n\n<div  class=\"purdue-home-image-slider section has-gray-background \" data-columns=\"3\">\n    <div class=\"container\">\n        <div class=\"glide\">\n            <div class=\"glide__live sr-only\"\n                 aria-live=\"polite\"\n                 aria-atomic=\"true\">\n            <\/div>\n            <div class=\"glide__track\" data-glide-el=\"track\">\n                <div class=\"glide__slides\">\n                                                                                                        <div class=\"glide__slide\">\n                                    <figure class=\"image\">\n                                        <img decoding=\"async\" class=\"is-16by9\"                                                src=\"https:\/\/www.purdue.edu\/fnr\/hoverman\/wp-content\/uploads\/2021\/12\/AcuteToxicity1-1.png\"\n                                                alt=\"\" \/>\n                                                                                    <figcaption>Algae Culturing for Water Fleas<\/figcaption>\n                                                                            <\/figure>\n                                <\/div>\n                                                                                                                <div class=\"glide__slide\">\n                                    <figure class=\"image\">\n                                        <img decoding=\"async\" class=\"is-16by9\"                                                src=\"https:\/\/www.purdue.edu\/fnr\/hoverman\/wp-content\/uploads\/2021\/12\/AcuteToxicity2.png\"\n                                                alt=\"\" \/>\n                                                                                    <figcaption>Husbandry Tanks for Fish<\/figcaption>\n                                                                            <\/figure>\n                                <\/div>\n                                                                                                                <div class=\"glide__slide\">\n                                    <figure class=\"image\">\n                                        <img decoding=\"async\" class=\"is-16by9\"                                                src=\"https:\/\/www.purdue.edu\/fnr\/hoverman\/wp-content\/uploads\/2021\/12\/AcuteToxicity3.png\"\n                                                alt=\"\" \/>\n                                                                                    <figcaption>Fish Eggs<\/figcaption>\n                                                                            <\/figure>\n                                <\/div>\n                                                                                                                <div class=\"glide__slide\">\n                                    <figure class=\"image\">\n                                        <img decoding=\"async\" class=\"is-16by9\"                                                src=\"https:\/\/www.purdue.edu\/fnr\/hoverman\/wp-content\/uploads\/2021\/12\/AcuteToxicity4.png\"\n                                                alt=\"\" \/>\n                                                                                    <figcaption>Experimental Setup for Acute Toxicity Trials<\/figcaption>\n                                                                            <\/figure>\n                                <\/div>\n                                                                                                                <div class=\"glide__slide\">\n                                    <figure class=\"image\">\n                                        <img decoding=\"async\" class=\"is-16by9\"                                                src=\"https:\/\/www.purdue.edu\/fnr\/hoverman\/wp-content\/uploads\/2021\/12\/AcuteToxicity5.png\"\n                                                alt=\"\" \/>\n                                                                                    <figcaption>Experimental Setup for Acute Toxicity Trials<\/figcaption>\n                                                                            <\/figure>\n                                <\/div>\n                                                                                        <\/div>\n            <\/div>\n                        <div class=\"slider-controls\">\n                <button class=\"glide__arrow arrow--left\">previous<\/button>\n                <div class=\"glide__bullets\" data-glide-el=\"controls[nav]\">\n                                                                        <button class=\"glide__bullet slider__bullet\"\n                                    data-glide-dir=\"=0\"\n                                    aria-label=\"slide 1\"><\/button>\n                                                    <button class=\"glide__bullet slider__bullet\"\n                                    data-glide-dir=\"=1\"\n                                    aria-label=\"slide 2\"><\/button>\n                                                    <button class=\"glide__bullet slider__bullet\"\n                                    data-glide-dir=\"=2\"\n                                    aria-label=\"slide 3\"><\/button>\n                                                    <button class=\"glide__bullet slider__bullet\"\n                                    data-glide-dir=\"=3\"\n                                    aria-label=\"slide 4\"><\/button>\n                                                    <button class=\"glide__bullet slider__bullet\"\n                                    data-glide-dir=\"=4\"\n                                    aria-label=\"slide 5\"><\/button>\n                                                            <\/div>\n                <button class=\"glide__arrow arrow--right\">next<\/button>\n            <\/div>\n        <\/div>\n    <\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-637","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.purdue.edu\/fnr\/hoverman\/wp-json\/wp\/v2\/pages\/637","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.purdue.edu\/fnr\/hoverman\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.purdue.edu\/fnr\/hoverman\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.purdue.edu\/fnr\/hoverman\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.purdue.edu\/fnr\/hoverman\/wp-json\/wp\/v2\/comments?post=637"}],"version-history":[{"count":12,"href":"https:\/\/www.purdue.edu\/fnr\/hoverman\/wp-json\/wp\/v2\/pages\/637\/revisions"}],"predecessor-version":[{"id":1209,"href":"https:\/\/www.purdue.edu\/fnr\/hoverman\/wp-json\/wp\/v2\/pages\/637\/revisions\/1209"}],"wp:attachment":[{"href":"https:\/\/www.purdue.edu\/fnr\/hoverman\/wp-json\/wp\/v2\/media?parent=637"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}