Standard Operating Procedures

The OSHA Laboratory Standard (i.e. Chemical Hygiene Plan) requires SOPs relevant to safety and health considerations to be prepared and followed when laboratory work involves the use of hazardous chemicals. Other regulatory programs may also require SOPs.

Standard operating procedures (SOPs) are written instructions that detail the steps taken to perform a given operation and include information about potential hazards and how the hazards will be mitigated. It is prudent to have SOPs for work involving chemical, biological, animal, and radiological hazards; radiation producing devices; and other physical hazards. SOPs should be written by personnel who are most knowledgeable with the experimental process and associated hazards. However, the Laboratory Supervisor is ultimately responsible for approving SOPs regardless of who prepared them.

The SOP templates available below have been prepared by REM using templates developed by the University of California (Los Angeles) Environmental Health and Safety Department. These templates are for common and hazardous operations. They are incomplete as written; they must be customized. Instructions for completion are included in each template. The templates are part of an ongoing effort by REM to provide SOP guidance. Our template list will continue to grow to incorporate more hazards. Laboratories, shops, and other areas with hazardous operations are encouraged to develop their own SOPs using this template format.

Contact REM at (765) 496-3072 if you need assistance or would like to submit a SOP to be considered for making into a template and posting below.

Chemicals Requiring SOPs:

  1. 2-Mercaptoethanol
  2. Acetic Anhydride
  3. Acrolein (2-Propenal)
  4. Acutely Toxic Materials
  5. Alkali Metals
  6. Animal Research High Hazards
  7. Ammonia
  8. Aqua Regia
  9. Base Bath
  10. Benzene
  11. Biosafety Level 2
  12. Boron Tribromide
  13. Boron Trichloride
  14. Boron Trifluoride
  15. Bromine
  16. Chemical Spill Response and Cleanup (Non Emergency)
  17. Chlorine Gas
  18. Chloroform
  19. Chromerge (Chromic acid solution)
  20. Compressed Gases
  21. Corrosives
  22. Dangerous When Wet Materials
  23. Diethyl Ether
  24. Ethidium Bromide
  25. Ethylene Oxide
  26. Flammable and Combustible Liquids
  27. Flammable  Solids
  28. Formaldehyde
  29. GSK
  30. Hexafluoro-2-Propano
  31. Hydrogen Fluoride (HF)
  32. Hydrogen Gas
  33. Hydrogen Peroxide
  34. Hydrogen Sulfide
  35. Isophorone Diisocyanate
  36. Liquid Nitrogen
  37. Lithium Alkyl Compounds
  38. Lithium Metal
  39. Mercury
  40. Methylene Chloride (Dichloromethane)
  41. Methyltrichlorosilane
  42. Nanoparticles
  43. Nitrate Salts
  44. Nitric Acid
  45. Nitric Oxide
  46. Osmium Tetroxide
  47. Oxidizers
  48. Peracetic Acid (Peroxyacetic Acid)
  49. Perchloric Acid
  50. Perfluorodecyltrichlorosilane
  51. Phenylmethanesulfonyl Fluoride (PMSF)
  52. Piranha Solution
  53. Potassium Cyanide
  54. Propylene Oxide
  55. Pyrophorics
  56. Sodium Azide
  57. Sulfuric Acid
  58. Toluene
  59. Zirconium Powder