Standard Operating Procedures

The OSHA Laboratory Standard (i.e. Chemical Hygiene Plan) requires SOPs relevant to safety and health considerations to be prepared and followed when laboratory work involves the use of hazardous chemicals. Other regulatory programs may also require SOPs.

Standard operating procedures (SOPs) are written instructions that detail the steps taken to perform a given operation and include information about potential hazards and how the hazards will be mitigated. It is prudent to have SOPs for work involving chemical, biological, animal, and radiological hazards; radiation producing devices; and other physical hazards. SOPs should be written by personnel who are most knowledgeable with the experimental process and associated hazards. However, the Laboratory Supervisor is ultimately responsible for approving SOPs regardless of who prepared them.

The SOP templates available below have been prepared by REM using templates developed by the University of California (Los Angeles) Environmental Health and Safety Department. These templates are for common and hazardous operations. They are incomplete as written; they must be customized. Instructions for completion are included in each template. The templates are part of an ongoing effort by REM to provide SOP guidance. Our template list will continue to grow to incorporate more hazards. Laboratories, shops, and other areas with hazardous operations are encouraged to develop their own SOPs using this template format.

Contact REM at (765) 496-3072 if you need assistance or would like to submit a SOP to be considered for making into a template and posting below.

Chemicals Requiring SOPs:

  1. 2-Mercaptoethanol
  2. Acrolein (2-Propenal)
  3. Acutely Toxic Materials
  4. Alkali Metals
  5. Animal Research High Hazards
  6. Ammonia
  7. Aqua Regia
  8. Base Bath
  9. Benzene
  10. Biosafety Level 2
  11. Boron Tribromide
  12. Boron Trichloride
  13. Boron Trifluoride
  14. Bromine
  15. Chloroform
  16. Chlorine Gas
  17. Chromerge (Chromic acid solution)
  18. Compressed Gases
  19. Corrosives
  20. Dangerous When Wet Materials
  21. Diethyl Ether
  22. Ethidium Bromide
  23. Ethylene Oxide
  24. Flammable and Combustible Liquids
  25. Flammable  Solids
  26. Formaldehyde
  27. Hydrogen Fluoride (HF)
  28. Hydrogen Gas
  29. Hydrogen Peroxide
  30. Hydrogen Sulfide
  31. Isophorone Diisocyanate
  32. Liquid Nitrogen
  33. Lithium Alkyl Compounds
  34. Lithium Metal
  35. Mercury
  36. Methylene Chloride (Dichloromethane)
  37. Methyltrichlorosilane
  38. Nanoparticles
  39. Nitrate Salts
  40. Nitric Acid
  41. Nitric Oxide
  42. Osmium Tetroxide
  43. Oxidizers
  44. Peracetic Acid (Peroxyacetic Acid)
  45. Perchloric Acid
  46. Perfluorodecyltrichlorosilane
  47. Piranha Solution
  48. Potassium Cyanide
  49. Propylene Oxide
  50. Pyrophorics
  51. Sodium Azide
  52. Sulfuric Acid
  53. Toluene
  54. Zirconium Powder