February 12, 2025
Covalent-allosteric inhibitors (CAIs) may achieve the best of both worlds: increased potency, long-lasting effects, and reduced drug resistance typical of covalent ligands, along with enhanced specificity and decreased toxicity inherent in allosteric modulators.
Covalent-Allosteric Inhibitors: Do We Get the Best of Both Worlds?
February 11, 2025
Ribonucleic acid, commonly known as RNA, is involved in many biological functions, and some, including gene silencing, are utlitized to cure diseases. RNA has recently gained attention as a promising drug target. Unfortunately, only a small fraction of RNA structures have been determined experimentally, and the process of uncovering these structures requires intense time and effort. Using this time scale, the structures of many life-saving RNA may not be discovered for years. As a result, there is a significant gap between the types of known RNA and the available structural data.
Purdue researchers advance RNA medical discovery decades ahead of schedule
February 11, 2025
Purdue University has appointed Purdue Professor of Toxicology Aaron Bowman as the new dean of the College of Health and Human Sciences, effective from February 10, 2025.
Purdue’s College Of Health And Human Sciences Gets New Dean - Aaron Bowman
February 7, 2025
The College of Veterinary Medicine is hosting a public health conference, titled Antimicrobial Resistance Conference: Determinants, Dynamics and Deterrence of Drug Resistance, in the Stewart Center on Feb. 26-27.
Purdue’s College of Veterinary Medicine to host educational public health conference
February 7, 2025
Dr. Wendy Beauvais, Assistant Professor for the College of Veterinary Medicine at Purdue University, will be conducting a seminar on "Infectious Disease Spillover Risks from Livestock to Wildlife Case Study: Saiga Saiga Tatarica".
FNR Seminar Series - Infectious Disease Spillover Risks from Livestock to Wildlife Case Study: Saiga Saiga Tatarica
February 7, 2025
In Alzheimer’s disease, microglia pack on fat, which impairs phagocytosis. Now, scientists led by Christiane Ruedl of Nanyang Technological University, Singapore, report that blocking lipid buildup in these cells restores their capacity to engulf Aβ, leading to fewer plaques in the brains of APP knock-in mice. Their paper ran in the February 5 Science Advances.
February 7, 2025
The Purdue University Board of Trustees on Friday (Feb. 7) ratified two faculty appointments and also approved two new degree programs, resolutions of appreciation and a naming.
Trustees ratify faculty positions; approve new degree programs, resolutions of appreciation and naming
February 6, 2025
As a second strain of bird flu has spread to dairy cows, influenza experts tell Newsweek that consumers should not be concerned about drinking pasteurized milk.
Can You Get Bird Flu From Drinking Milk? What to Know as Cows Are Infected
February 5, 2025
egistration is open for faculty to attend the Westwood Lecture Series on Feb. 19. Two leading Purdue researchers will discuss the university’s growing role in the next revolution of pharmaceutical manufacturing from 4:30-5:30 p.m. at Westwood, the Purdue president’s residence.
Registration open for Feb. 19 Westwood Lecture on advanced pharmaceutical manufacturing
February 3, 2025
The acquisition of the Hitachi S-3400N Type II variable pressure scanning electron microscope with Deben Peltier Coolstage provides a powerful imaging technique to observe and characterize pharmaceutical drug substances and drug products.
Improved Pharma Announces New Scanning Electron Microscopy (SEM) Capabilities in Collaboration with Chemical Microscopy, LLC.
