The Purdue Institute of Inflammation, Immunology, and Infectious Disease (PI4D) leverages the significant diversity of life sciences, physical sciences, and engineering on campus to invent and integrate basic immunologic advances, new diagnostics, probe basic biological and inflammatory processes, and to develop and commercialize novel intervention methods to control an array of chronic inflammatory conditions, cancer and infectious diseases. Purdue has deep expertise in molecular detection technologies, primarily through engineering, analytical chemistry, and physics. Basic research in inflammation, immunology and infectious disease, chiefly at the single investigator level, is scattered widely in multiple colleges and departments. Purdue brings a unique opportunity on the control of pathogens with its position in agriculture and the focus on feeding the world. Finally there is a growing community of chemical biologists, medicinal chemists, and life scientists who are focused on translating cell and animal/plant-based discovery into therapeutics and vaccines. These communities of researchers are scattered and have not been linked together through concerted efforts to form a coherent group with shared goals. As a result, the overall research output from the university in this area falls short of national and international recognition, but displays pockets of significant international recognition. This Purdue Pillar of Excellence will develop a research agenda that links and coordinates these diverse but complementary disciplines to focus on detecting, diagnosing, investigating, and treating disease in both plants and animals with a driven desire to commercialize these discoveries and inventions. This coordinated research portfolio will provide a platform for the development of graduate training programs that intersect disciplines and focus on discovery with delivery. This Pillar will be loosely modeled on Purdue’s Center for Cancer Research and will integrate many of its activities with the PCCR.

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