Ingestive Behavior Research Center

The Integrative Research Program

The hallmark of research training at the IBRC is its integrative and collaborative approach.  Participants in the IBRC training program have the opportunity to participate in a wide range of projects related to eating behavior and its disorders.  Broad research areas include:


Recent Publications:

Kola Ajuwon

Hausman GJ, Dodson MV, Ajuwon K, Azain M, Barnes KM, Guan LL, Jiang Z, Poulos SP, Sainz RD, Smith S, Spurlock M, Novakofski J, Fernyhough ME, Bergen WD. Board-invited review: the biology and regulation of preadipocytes and adipocytes in meat animals. Journal of Animal Science, 2010; 87(4), 1218-1246.

Ajuwon K, Banz W, Winters TA. Stimulation with Peptidoglycan induces interleukin 6 and TLR2 expression and a concomitant downregulation of expression of adiponectin receptors 1 and 2 in 3T3-L1 adipocytes. Journal of Inflammation (Lond)., 6(8). 2010.

James Binkley

Binkley J, Golub A. consumer demand for nutrition versus taste in four major food categories. Agricultural Economics, forthcoming.

Carol Boushey

Fialkowski MK, McCrory MA, Roberts SM, Tracy JK, Grattan LM, Boushey, CJ. Estimated nutrient intakes from food generally do not meet dietary reference intakes among adult members of Pacific Northwest tribal nations, Journal of Nutrition, 2010; 140(5):992-8 (ISI 3.69).

Yang YJ, Martin, BR, Boushey, CJ. Development and evaluation of a brief calcium assessment tool (BCAT) for adolescents. Journal of American Dietetic Association, 2010; 110:111-115 (ISI 2.87).

Six BL, Schap TE, Zhu FM, Mariappan, A, Delp EJ, Ebert DS, Kerr DA, Boushey CJ. Evidence-based development of a mobile telephone food record. Journal of American Dietetic Association, 2010; 110:74-79 (ISI 2.87).

Kim Buhman

Zhu J, Lee B, Buhman, KK, Cheng, JX. Direct observation of dynamic triglyceride pool in mouse enterocytes during dietary fat absorption by coherent anti-Stokes Raman scattering imaging. Journal of Lipid Research, 2009; 50(6): 1080-9.

Lee B-G, Zhu J, Wolins N, Cheng JX, Buhman KK. Differential association of adipophilin and TIP47 with cytoplasmic lipid droplets in mouse enterocytes during dietary fat absorption. Biochimica et Biophysica Acta, 2009; 179(12): 1173-80.

Wayne Campbell

Leidy HJ, Armstrong, CLH, Tang M, Mattes RD, Campbell WW. The influence of higher protein intake and eating frequency on appetite control in overweight and obese men. Obesity (in press) [March 25, 2010, Epub ahead of print].

Leidy HJ, Apolzan JW, Mattes RD, Campbell WW. Food form and portion size affect postprandial appetite sensations and hormonal responses in healthy, nonobese, older adults. Obesity, 2010; 18(2): 293-299. [July 23, 2009, Epub ahead of print].

Julia Chester

Chester JA, Gallt LE. Pentylenetetrazol produces a conditioned place aversion to alcohol withdrawal in mice, Pharmacology, Biochemistry and Behavior, 2010; 95(2), 258-65. Epub Feb 9, 2010.

Powers MS, Barrenha GD, Mlinac NS, Barker EL, Chester JA. Effects of the novel endocannabinoid uptake inhibitor, LY2183240, on fear-potentiated startle and alcohol-seeking behaviors in mice selectively bred for high alcohol preference. Psychopharmacology, 2010, in press.

Robert Considine

Cassady BA, Hollis JH, Fulford AD, Considine RV, Mattes RD. Mastication of almonds: effects of lipid bioaccessibility, appetite, and hormone response. American Journal of Clinical Nutrition, 2009; 89:794-800.

Bruno C, Fulford AD, Potts JR, McClintock R, Jones, RM, Cacucci BM, Gupta CE, Peacock M, Considine RV. Serum markers of bone turnover are increased at six and eighteen months following Roux-En-Y bariatric surgery: correlation with the reduction in leptin. Journal of Clinical Endocrinology and Metabolism, 2010; 95:159-66.

Bragulat V, Dzemidzic M, Bruno C, Cox CA, Talavage T, Considine RV, Kareken DA. Food-related odor probes of brain reward circuits during hunger: a pilot fMRI study. Obesity (Silver Spring), 2010; 18:1566-71.

James Daniel

Daniel JR. Advances in development of fat replacers and low fat products in innovation in food engineering: new techniques and products, Ribeiro, Jr., CP, Passos, ML (eds.), CRC Press, Boca Raton, FL, 657-684, 2010.

Mario Ferruzzi

Ferruzzi MG. The influence of beverage composition on delivery of phenolic compounds from coffee and tea. Physiology & Behavior, Apr 26, 2010; 100(1):33-41. Epub Feb 6, 2010.

Neilson AP, George JC, Janle EM, Mattes RD, Rudolph R, Matusheski NV, Ferruzzi, MG. Influence of chocolate matrix composition on cocoa flavan-3-ol bioaccessibility in vitro and bioavialability in humans. Journal of Agricultural Food Chemistry, Oct 28, 2009; 57(20):9418-26.

Edward Fox

Biddinger JE, Fox EA. Meal parameters and vagal gastrointestinal afferents in mice that experienced early postnatal overnutrition. Physiology & Behavior, 2010; 101-184-191.

Fox EA, Murphy MC. Factors regulating vagal sensory development: potential role in obesities of developmental origin. Physiology & Behavior, 2008; 94, 90-104.

Fox EA. The labeled line / basic taste versus across-fiber pattern debate: a red herring? Behavioral & Brain Sciences, 2008; 31, 79-80.

Bruce Hamaker

Rose DJ, Venema K, Keshavarzian A, Hamaker BR. Starch-entrapped microspheres show a beneficial fermentation profile and decrease in potentially harmful bacteria during in vitro fermentation in fecal microbiota obtained from patients with inflammatory bowel disease. British Journal of Nutrition, 2010; 103:1514-1524 (IF=3.446).

Rose DJ, Patterson JA, Hamaker BR. Structural differences among alkali-soluble arabinoxylans from maize (Zea Mays), rice (Oryza sativa), and wheat (Triticum aestivum) brans influence human fecal fermentation profiles. Journal of Agricultural Food Chemistry, 2010; 58:493-499 (IF2.469).

Venkatachalam M, Kushnick MR, Zhang G, and Hamaker BR. Biopolymer-entrapped starches as a novel approach to vary blood glucose profiles. Journal of American College of Nutrition, 2009; 28:583-590 (IF=2.362).

Elsa Janle

Neilson AP, Sapper TN, Janle EM, Rudolph R, Matusheski NV, Ferruzzi MG. Chocolate matrix factors modulate the pharmacokinetic behavior of cocoa flavan-3-ol phase II metabolites following oral consumption by Sprague-Dawley rats. Journal of Agriculgural Food Chemistry, 2010; 58, 6685-6691.

Janle EM, Lila MA, Grannan M, Wood L, Higgins A, Yousef GG, Rogers RB, Kim H, Jackson GS, Ho L, Weaver CM. Pharmacokinetics and tissue distribution of 14C labeled grape polyphenols in the periphery and the central nervous system following oral administration. Journal of Medicinal Food, 2010; 13(4):926-933. DOI:10.1089/jmf.2009.0157.

David Kareken

Kareken DA, Liang T, Wetherill L, Dzemidzic M, Bragulat V, Cox C, Talavage T, O'Connor SJ, Foroud T. A polymorphism in GABRA2 is associated with medial frontal response to alcohol cues in an fMRI study. Alcoholism: Clinical and Experimental Research, (in press).

Bragulat V, Dzemidzic M, Bruno C, Cox CA, Talavage TA, Considine RV, Kareken DA. Food-related odor probes of brain reward circuits during hunger: a pilot fMRI. Obesity, 2010; 18,1566-71.

Kareken DA, Bragulat V, Dzemidzic M, Cox C, Talavage T, Davidson D, O'Connor SJ. Family history of alcoholism mediates the frontal response to alcoholic drink odors and alcohol in at-risk drinkers. NeuroImage, Mar 2010; 50(1)267-276.

Kee-Hong Kim

Kim KH, Park Y. Food Components with anti-obesity effects. Annual Review of Food Science and Technology, 2011, (in press).

Kim CY, Le TT, Chen C, Cheng JX, Kim KH. Curcumin inhibits adipocyte differentiation through modulation of mitotic clonal expansion, Journal of Nutritional Biochemistry, 2010, (in press).

Kimberly Kinzig

Kinzig K, Hargrave SL. Adolescent activity-based anorexia increases anxiety-like behavior in adulthood. Physiology & Behavior, Sep 1, 2010, 1:101(2):269-76. Epub May 26, 2010.

Kinzig K, Honors MA, Hargrave SL, Davenport BM, Strader AD, Wendt D. Sensitivity to the anorectic effects of leptin is retained in rats maintained on a ketogenic diet despite increased adiposity. Neuroendocrinology, Jun 2, 2010 [Epub ahead of print].

Richard Mattes

Mattes RD, Shikany JM, Kaiser KA, Allison DB. Nutritively sweetened beverage comsumption and body weight: a systematic review and meta-analysis of randomized experiments. Obesity Research, doi: 10.1111/j.1467-789X.2010.00755.x.

Mattes RD. Hunger and thirst: issues in measurement and prediction of eating and drinking. Physiology & Behavior, 2010; 100: 22-32.

Megan McCrory

McCrory MA, Howarth NC, Robert SB, Huang TTK. Eating frequency and energy regulation in free-living adults consuming self-selected diets. Journal of Nutrition, 2010, Dec 1, doi:10.3945/jn.114991 (epub before print).

McCrory MA, Hamaker BR, Lovejoy JC, Eicheldoerfer PE. Pulse consumption, satiety, and weight management. Advances in Nutrition, 2010; 1:17-30.

Robert Phillips

Phillips RJ, Walter GC, Powley TL. Age-related changes in vagal afferents innervating the gastrointestinal tract. Autonomic Neuroscience: Basic and Clinical, 2010; 153:90-98.

Phillips RJ, Walter GC, Ringer BE, Higgs KM, Powley TL. Alpha-synuclein immunopositive aggregates in the myenteric plexus of the aging Fischer 344 rat. Experimental Neurology, 2009; 220:109-119.

Philip Troped

Troped PF, Wilson J, Matthews CE, Cromley EK, Melly SJ. The built environment and location-based physical activity. American Journal of Preventive Medicine, 2010; 38(4):429-438.

Bruce Watkins

Bharadwaj AS, Hart SD, Brown BJ, Li Y, Watkins BA, Brown PB. Dietary source of stearidonic acid promotes higher muscle DHA concentrations than linolenic acid in hybrid striped bass. Lipids, January 2010; 45(1):21-7. Epub Nov 22, 2009.

Lee L, Alloosh M, Saxena R, Van Alstine W, Watkins BA, Klaunig JE, Sturek M, Chalasani N. Nutritional model of steatohepatitis and metabolic syndrome in the Ossabaw miniature swine. Hepatology, July 2009; 50(1)56-67.

Connie Weaver

Weaver CM. Role of dairy beverages in the diet. Physiology & Behavior, 2010; 100:63-66.

Singh R, Martin BR, Hickey Y, Teegarden D, Campbell WW, Craig BA, Schoeller DA, Kerr DA, Weaver CM. Comparison of self-reported and measured metabolizable energy intake with total energy expenditure in overweight teens. The American Journal of Clinical Nutrition, 2009; 89:1744-50.

Wei Zheng

Kanoski SE, Zhang Y, Zheng W, Davidson TL. Effects of a high-energy diet on hippocampal-dependent Pavlovian discrimination learning and blood-brain barrier integrity. Hippocampus, 2010, (in press).

About the IBRC

The Ingestive Behavior Research Center at Purdue University is unique in providing an interdisciplinary research and training environment that promotes excellence in the analysis of ingestive behavior and its disorders.

Our Vision

Individual and population-based health practices will be optimized by advancing understanding of the controls of ingestive behavior.

IBRC Executive Committee

Current Events

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Cresta Cates
Administrative Assistant
Purdue University
Stone Hall, Room 220
700 W. State Street
West Lafayette, IN 47907-2059
(765) 494-5735 phone
(765) 494-0674 fax