October 17, 2024
Symptoms and disease progression of Rett syndrome are different in females than males. A new study shows why it is important to understand these differences to develop better treatments.
Study shows that Rett syndrome in females is not just less severe, but different
October 17, 2024
Increased risk for autism appears to be linked to the Y chromosome, a study has found, offering a new explanation for the greater prevalence of autism in males.
October 15, 2024
Aging is a leading cause of disease and disability. This special Research in Context feature explores research into the biology of aging, including how to measure its speed and progression and ways it might be slowed down or even reversed.
October 10, 2024
The risk of asthma in the child can be reduced by nearly half if the mother engages in active physical exercise at least three times a week during pregnancy, compared to a child of a mother who is less active, a new study shows.
Maternal exercise during pregnancy may protect the child against asthma
October 9, 2024
Hypertensive disorders of pregnancy, the second leading cause of maternal deaths worldwide, may be sending a significantly higher number of pregnant people to the emergency department.
Spike in emergency visits for life threatening pregnancy complication, study suggests
October 9, 2024
A new study has found some cancers to be slightly more frequent in people with multiple sclerosis (MS) than in people without MS. Types of cancers found to have a small increased risk include bladder, brain and cervical cancers. The study does not prove that MS increases a person's risk of cancer. It only shows an association.
October 9, 2024
Genome-wide association studies have great potential for advancing our understanding of the genetic background of diseases, but so far, few association studies have focused on maternal and newborn diseases, and most have been based on predominantly European populations. To fill these gaps, researchers generated and analyzed full-genome DNA sequences from non-invasive prenatal blood tests collected from over 25,000 pregnant women, all of whom were Han Chinese.
Genetic analysis of 25,000 Chinese mothers and infants reveals unique genes associated with disease risk
October 9, 2024
Triple negative breast cancer (TNBC) remains the most aggressive and deadly type of breast cancer, but new findings from cancer researchers are pointing the way toward therapeutic strategies that could be tested in clinical trials in the future. Using patient-derived samples in pre-clinical work, researchers discovered that by combining two therapeutic agents they could nudge TNBC cells into a more treatable state.
New therapeutic strategy identified for triple negative breast cancer
October 8, 2024
Scientists have long wondered why animals get the DNA inside their mitochondria, the cell's energy center, only from their mothers. New research explains why and offers hope for treating mitochondrial disorders.
October 8, 2024
Researchers have discovered that the kinase enzyme DAPK3 is elevated in triple-negative breast cancer cells where it regulates migration of the cancerous cells. The findings prompted the team to investigate whether medications directed at DAPK3 could have therapeutic value.
DAPK3 emerges as a new regulator of migration of triple-negative breast cancer cells