PhD Tufts University 1993
Our research interests include human nutrition and exercise studies on protein, carbohydrate and energy metabolism, dietary protein and energy requirements, body composition, obesity, weight loss, muscle strength, and muscle function with special emphasis on aging. We are also interested in how nutrition, exercise, and aging impact appetite and ingestive behaviors. Our recent research suggests that older people who habitually consume the Recommended Dietary Allowance for protein experience subtle declines in skeletel muscle size. Thus we seek to find the optimal protein intake for older and elderly people to consume. Our research also focuses on how protein metabolism, body composition, and glucose metabolism change in older people with changes in protein intake, body weight, and exercise (especially strength training). We are also interested in evaluating the effectiveness of compounds that are promoted to have ergogenic properties. The potential importance of the physical form of food (e.g. liquid versus solid) on appetite, ingestive behaviors, energy balance, and body weight control is also of great interest to our research team.
Our research includes the use of traditional metabolic balance techniques (with strict dietary control possible in a metabolic research kitchen), stable isotope infusion techniques (to measure in vivo acid turnover and incorporation into muscle tissues), whole body composition (hydrostatic weighing, plethysmography, dual x-ray absorptiometry, deuterium oxide dilution), the muscle biopsy technique (to obtain small samples of human skeletal muscle), and indirect calorimetry (to measure resting and exercise energy expenditure). We also highly value collaboration within and outside of Purdue to expand our interests, expertise, and research capabilities, as become available.
Topics in Nutrition, Fitness, and Health (F&N 488) - Review of current literature in nutrition as it relates to fitness and health with in-depth analysis of obesity. Exploration of career opportunities in nutrition, fitness, and health. Geriatric Nutrition (F&N 580) - Nutritional needs and problems of the aging, community and institutional food programs.
2021 - U.S. Whey Protein Research Consortium
2021 - National Cattlemen's Beef Association
2021 - Mushroom Council
2020 - Foundation for Meat & Poultry Research & Education
2020 - National Cattlemen's Beef Association
2020 - Mushroom Council
2019 - Colorado State University, subcontract of the National Cattlemen's Beef Association
2018 - National Institutes of Health
Wang Y, Hill ER, Campbell WW, O-Connor LE. Plant- And Animal-based Protein-rich Foods And Cardiovascular Health. Curr Atheroscler Rep. Published Online: 25 March 2022. PMID 35332443
Bergia RE, Giacco R, Hjorth T, Biskup I, Zhu W, Costabile G, Vitale M, Campbell WW, Landberg R, Riccardi G. Differential Glycemic Effects Of Low- Versus High-Glycemic Index Mediterranean-Style Eating Patterns In Adults At Risk For Type 2 Diabetes: The MEDGI-Carb Randomized Controlled Trial. Nutrients. 2022 Feb 8;14(3):706. PMID: 35277067
Krishnan S, O'Connor LE, Wang Y, Gertz ER, Campbell WW, Bennett BJ. Adopting A Mediterranean-style Eating Pattern With Low, But Not Moderate, Unprocessed, Lean Red Meat Intake Reduces Fasting Serum Trimethylamine N-oxide (TMAO) In Adults Who Are Overweight Or Obese. Br J Nutr. 2021 Nov 26:1-21. PMID: 34823615
Jun S, Cowan AE, Dwyer JT, Campbell WW, Thalacker-Mercer AE, Gahche JJ, Bailey RL. Dietary Protein Intake Is Positively Associated With Appendicular Lean Mass And Handgrip Strength Among Middle-Aged US Adults. J Nutr. 2021 Dec 3;151(12):3755-3763. PMID: 34494110
Sutliff AK, Saint-Cyr M, Hendricks AE, Chen SS, Doenges KA, Quinn K, Westcott J, Tang M, Borengasser SJ, Reisdorph RM, Campbell WW, Krebs NF, Reisdorph NA. Lipidomics-Based Comparison Of Molecular Compositions Of Green, Yellow, And Red Bell Peppers. Metabolites. 2021 Apr 14;11(4):241. PMID: 33919953
O'Connor LE, Kim JE, Clark CM, Zhu W, Campbell WW. Effects Of Total Red Meat Intake On Glycemic Control And Inflammatory Biomarkers: A Meta-Analysis Of Randomized Controlled Trials. Adv Nutr. 2021 Feb 1;12(1):115-127. PMID: 32910818
Hudson JL, Zhou J, Campbell WW. Adults Who Are Overweight Or Obese And Consuming An Energy-Restricted Healthy US-Style Eating Pattern At Either The Recommended Or A Higher Protein Quantity Perceive A Shift From "Poor" To "Good" Sleep: A Randomized Controlled Trial. J Nutr. 2020 Dec 10;150(12):3216-3223. PMID: 33096550
Bergia RE, Campbell WW, Roseguini BT, Kim JE. A High-protein Meal Does Not Improve Blood Pressure Or Vasoactive Biomarker Responses To Acute Exercise In Humans. Nutr Res. 2020 Sep;81:97-107. PMID: 32949918
Byers AW, Connolly G, Campbell WW. Vitamin D Status And Supplementation Impacts On Skeletal Muscle Function: Comparisons Between Young Athletes And Older Adults. Curr Opin Clin Nutr Metab Care. 2020 Nov;23(6):421-427. PMID: 32925179
Bergia RE 3rd, Biskup I, Giacco R, Costabile G, Gray S, Wright A, Vitale M, Campbell WW, Landberg R, Riccardi G. The MEDGICarb-Study: Design Of A Multi-center Randomized Controlled Trial To Determine The Differential Health-promoting Effects Of Low- And High-glycemic Index Mediterranean-style Eating Patterns. Contemp Clin Trials Commun. 2020 Aug 13;19:100640. PMID: 32885091.
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