Daisuke Kihara
Professor, Department of Biological Sciences and Department of Computer Science
PhD, Kyoto University, Japan
dkihara@purdue.edu
765-496-2284
HOCK 229
kiharalab.org
Computational and Systems Biology
Biomolecular Structure and Biophysics
Active Mentor - currently hosting PULSe students for laboratory rotations and recruiting PULSe students into the laboratory; serves on preliminary exam committees
Current Research Interests:
Protein Bioinformatics. Our lab develops and applies computational tools for building protein 3D structure models, protein complexes, structure modeling for cryo-electron microscope density data, drug screening, and protein function prediction. We use various machine learning and computational biophysics approaches in the tools.
Selected Publications:
Genki Terashi & Daisuke Kihara, De novo main-chain modeling for EM maps using MAINMAST. Nature Communications, 9: 1618 (2018)
Lenna X. Peterson, Yoichiro Togawa, Juan Esquivel-Rodriguez, Genki Terashi, Charles Christoffer, Amitava Roy, Wooong-Hee Shin, & Daisuke Kihara, Modeling the assembly order of multimeric heteroprotein complexes. PLoS Comput. Biol., 14:e1005937 (2018)
Ishita K. Khan, Mansurul Bhuiyan, & Daisuke Kihara, DextMP: deep dive into text for predicting moonlighting proteins. Bioinformatics, 33: i83-i91 (2017)
Lenna X. Peterson, Amitava Roy, Charles Christoffer, Genki Terashi, & Daisuke Kihara , Modeling disordered protein interactions from biophysical principles. PLoS Computational Biol., 13: e1005485, (2017)
Lyman Monroe, Genki Terashi, & Daisuke Kihara, Variability of protein structure models from electron microscopy. Structure, 25: 592-602 (2017)
- Faculty Profile
