Majid Kazemian
Kazemian@purdue.edu
765-494-9350
kazemianlab.com
Microbiology, Immunology and Infectious Diseases
Computational and Systems Biology
Active Mentor - currently hosting PULSe students for laboratory rotations and recruiting PULSe students into the laboratory; serves on preliminary exam committees
Current Research Interests:
We are interested in studying underlying mechanism of autoimmune diseases such as rheumatoid arthritis, type I diabetes and asthma and infections including hepatitis and Epstein-Barr viruses leading to cancer. Our lab integrates computational and high throughput experimental approaches (e.g. RNA-seq, ChIP-seq, ATAC-seq, Hi-C) in to identify novel pathways, new host-pathogen interactions and regulatory noncoding RNAs (e.g. enhancer RNAs and circular RNAs) that could trigger disease.
Selected Publications:
M. Kolev, E. West, N. Kunz, E. Moseman, M. Balmer, J. Loetscher, S. Dimeloe, E. Rosser, L. Wedderburn, P. Lavender, A. Cope, L. Wang, D. Chauss, N. Moutsopoulos, M. Kaplan, D. McGavern, S. Holland, C. Hess, M. Kazemian, B. Afzali, C. Kemper, Immunity, (2020).
J. Martinez-Fabregas, S. Wilmes, L. Wang, M. Hafer, E. Pohler, J. Lokau, C. Garbers, A. Cozzani, J. Piehler, M. Kazemian, S. Mitra, I. Moraga-Gonzalez, "Kinetics of cytokine receptor trafficking determine signaling and functional selectivity", eLife, (2019).
S. Chakravorty, B. Yan, C. Wang, L. Wang, J. T. Quaid, C. F. Lin, S. D. Briggs, J. Majumder, D. A. Canaria, D. Chauss, G. Chopra, M. R. Olson, B. Zhao, B. Afzali, M. Kazemian, "Integrated Pan-Cancer Map of EBV-Associated Neoplasms Reveals Functional Host–Virus Interactions", Cancer Research, (2019).
- Faculty Profile