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Symposium on Frontiers in Biological Membranes
October 16-18, 2008
Dean’s auditorium and gallery, Pfendler Hall
Symposium PDF

Welcome by: Bill Cramer, Purdue University

Including symposia on:
  • Structure-Function of Membrane Proteins
    (Chair, Cynthia V. Stauffacher and Dinesh Yernool)

    Keynote Speaker, Professor William Weis, Department of Structural Biology, Stanford University, School of Medicine.
    "Structures of the beta2-adrenergic receptor"
    • Michael Rossmann, Department of Biological Sciences
      “Structure and function of membranes that envelope many viruses”
    • Jue Chen, Department of Biological Sciences
      “Crystal Structure of the E. coli Maltose Transporter”
    • Bill Cramer, Department of Biological Sciences
      “Structure Strategies for Transfer of Large Molecules across Membranes”

  • Membrane Receptors and Signaling
    (Chair, David Nichols and Chris Staiger)

    Keynote Speaker, Professor Richard Anderson, Department of Pharmacology, University of Wisconsin, Madison, WI.
    "PIP Kinases and Phosphoinositide Signaling"
    • David Nichols, Department of Medicinal Chemistry and Molecular Pharmacology
      “Folate-targeted therapeutics for cancer and inflammation”
    • Marietta Harrison, Department of Medicinal Chemistry and Molecular Pharmacology
      “Signaling from Golgi Membranes in T Cells”
    • R. Claudio Aguilar, Department of Biological Sciences
      “Signaling functions of the endocytic machinery”

  • Membrane Transport and Intracellular Trafficking
    (Chair, Christine Hrycyna)

    Keynote Speaker, Professor Dr. Robert Tampe, Institute of Biochemistry, Biocenter of the Johann Wolfgang Goethe-University, Frankfurt, Germany.
    "Structure and Function of TAP, the Transporter Associated with Antigen
    Processing"

    • Amy Davidson, Department of Chemistry
      “Using EPR to Detect Conformational Changes in the Maltose Transporter”
    • Angus Murphy, Dept. of Horticulture & Landscape Architecture, "The membrane-anchored M1.10 protease APM1 characterises an IRAP-like endosomal compartment in Arabidopsis"
    • Eric Barker, Department of Medicinal Chemistry and Molecular Pharmacology
      “Exploration of Drug Binding Sites on the Antidepressant- and Cocaine-Sensitive Serotonin Transporter”

  • Emerging Applications of Membrane Technologies
    (Chair, John Morgan)

    Keynote Speaker, Professor Horst Vogel, Ecole Polytechnique Fédérale de Lausanne Institut de Science Biomoléculaire, Lausanne, Switzerland.
    "Investigating Cellular Signaling at the Nanometer and Attoliter scale"
    • David Thompson, Dept. of Chemistry
      "Development of a Supported Membrane Sensor for the Detection of Isoprenylcarboxylmethyl transferase Activity"
    • Ken Ritchie, Dept of Physics
      "Single Molecule Imaging of the Dynamic Structure of Membranes in Living Cells"
    • Ji-xin Cheng, Dept. of Biomedical Engineering
      "Imaging Membrane by CARS microscopy: from domains in supported bilayer to demyelination in multiple sclerosis"
  • Structural/Membrane Biology Seminars
    Lilly 1-117 (check room listing) at 1:30 p.m. on Wednesdays

  • Department of Biological Sciences, 2008 Seminar Series
    MJIS 1001 at 4:00 p.m. on Wednesdays
Membrane Biology Seminars
Tuesday, January 20
11:00 a.m., LILY 1-117
Jochen Zimmer
Department of Cell Biology, Harvard Medical School
"Structural basis for SecA mediated protein translocation"
Tuesday, January 27
11:00 a.m., LILY 1-117
Pascal F. Egea
Dept. of Biochemistry & Biophysics, Univ. of California, San Francisco
"The targeting and assembly of membrane proteins"
Thursday, January 29
11:00 a.m., LILY 1-117
Seok-Yong Lee
Laboratory of Molecular Neurobiology and Biophysics, Rockefeller Univ.
"Structural and functional studies of voltage sensor proteins"
Monday, February 2
Cancer Center Seminar
3:30 p.m., STEW 202
Daniel Leahy
Department of Biophysics and Biophysical Chemistry, Johns Hopkins University, School of Medicine
"Structural basis for EGF/ErbB receptor signaling and ErbB-targeted cancer therapies"
Tuesday, February 3
11:00 a.m., LILY 1-117
Ariane Briegel
Division of Biology, California Institute of Technology
"Changing our view of bacterial ultrastructure with electron cryotomography"
Tuesday, February 10
Biophysics Training Grant
11:00 a.m., LILY 1-117
Vadim Cherezov
Department of Molecular Biology, Scripps Research Institute
Biophysical Discussion: "In meso crystallization"
Wednesday, February 11
1:30 p.m., LILY 1-117
Vadim Cherezov (Host: Bill Cramer)
Department of Molecular Biology, Scripps Research Institute
"Toward drug design: recent progress in understanding structure and function of G protein-coupled receptors"


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