Upcoming Events

Recent Activities of Faculty

Jue Chen, Dept. of Biological Sciences

• 06/22- 06/27/08, speaker at Gordon Conference on Bacterial Cell Surfaces, Colby-Sawyer College in New London, New Hampshire.
  "Structure and mechanism of the maltose transporter"
  
  
• 10/7/08, presenting an invited seminar to the Molecular Biophysics Discussion Group, University of Taxes Southwestern Medical Center
  "Structure and mechanism of the maltose transporter"
  
  
• 11/3/08, presenting an invited seminar at Harvard Medical School
  "Structure and mechanism of the maltose transporter"
  
  

W. A. Cramer, Dept. of Biological Sciences

• International Biophysics Congress, Long Beach CA, February 2-6, co-chaired the mini-symposium on Structure-Function of Oxidative Pathway Proteins, and Platform Session on Membrane Proteins, and presented a talk in the latter session on “The outer membrane translocon for nuclease colicins: higher resolution structure of the OmpF porin.”
  
  
• Eminent Scholar Lecture: "The hetero-oligomeric energy transducing membrane protein complexes, cytochromes bc1 and b6f of respiration and photosynthesis", Department of Biochemistry and Molecular Biology, Oklahoma State University, March 7, 2008.
  
  
• "Defining the Outer Membrane Translocon of the Nuclease Colicins" seminar at the Dept of Physiology & Biophysics, Albert Einstein College of Medicine, March 20, 2008-03-19.
  
  
• Lecture on "A bioinformatics analysis contributes to an improved cyanobacterial source for structure-function studies of the b6f complex." European Science Foundation Symposium on "Molecular Bioenergetics of Cyanobacteria: Towards a Systems Biology Level of Understanding." San Feliu de Guixiols, Spain, March 29-April 3, 2008
  
  
• “Properties of the prosthetic groups unique to cytochrome b6f complexes,” session on Photosynthetic Electron Transport, Gordon Conference on Biochemical Aspects of Photosynthesis, June 22-27, Mt. Holyoke College, So. Hadley, MA.
  
  
• “Crystal Structures of the OmpF Porin: Function in a Colicin Translocon,” FASEB Summer Research Conference on “Molecular Biophysics of Cellular Membranes,” July 20-25, Vermont Academy, Saxton’s River, Vermont.
  
  
• February 27- March 4, 2009, Biophysical Society, 53rd Annual Meeting, Boston, MA.
  
  
• Yamashita, E., D. Baniulis, H. Zhang, S. S. Hasan, O. Sharma, and W. A. Cramer. 2009. "Structure-function of Lipids and Quinone Tunnels in the Cytochrome b6f Complex." Bioenergetics Sub-group Symposium on "The Role of Lipids in Bioenergetic Functions."
  
  
• Yamashita, E., D. Baniulis, A. I. Zatsman, M. P. Hendrichs, and W. A. Cramer. 2009. Unique structure aspects of the cytochrome b6f complex. Mini-symposium on Electron Transfer and Energy Coupling Reactions in Organelles.
  
  
• Zakharov, S. D., O. Sharma, E. Yamashita, M. V. Zhalnina, K. A. Datsenko, S. Ess, B. L. Wanner, and W. A. Cramer. 2009. Protein Translocation across Membranes: Components of the Outer Membrane Translocon.
  
  

• "Structure and Mechanism of the Maltose (ABC) Transporter from E. coli", NIH; Membrane Protein Interest Group, Bethesda, Maryland, December 2007.
  
  
• "Structure and Mechanism of the Maltose (ABC) transporter from E.Coli", Kenyon College, Gambier, Ohio, April 2008.
  
  
• Chaired session on “Transporter/Channel Mechanisms,” and presented an invited talk in that session on “Structure and Mechanism of the ABC Maltose Transporter,” FASEB Summer Research Conference on “Molecular Biophysics of Cellular Membranes,” July 20-25, Vermont Academy, Saxton’s River, Vermont.
  
  
• Plenary Lecturer, 6th FEBS Advanced Lecture Course “ABC-Binding Cassette (ABC) Proteins; Austria. "Structure and Mechanism of action of the maltose transporter from E. coli" March 2008
  
  
• Symposium on Membrane Transport and Communication; Frankfurt, Germany. "Structure and Mechanism of the Maltose ABC transporter" November 2008
  
  
• "Structure and mechanism of the maltose (ABC) transporter from E. coli" University of Utah, Department of Biochemistry. November 2008
  
  
• Will serve as Chair of Gordon Research Conference on “Mechanisms of Membrane Transport”. June 2009
  
  
• Baker Symposium In Chemical Biology “Frontiers in Protein Chemistry: From Structure and Reaction to Cellular Function” Cornell University, Ithaca, NY. "Structure and mechanism of the maltose (ABC) transporter from E. coli" May 2010
  
  
• Session Chair, 2010 FASEB Meeting on Transport ATPases. July 2010
  
  

• “Folate Receptor-targeted Therapies for Cancer and Inflammation”, at Brigham Young University, Provo, UT, February 14, 2008.
  
  
• “Receptor-targeted Therapies for Cancer and Inflammation: Obstacles and Opportunities for Nanotechnology”, at The Future of Nanotechnology for Targeted Drug Delivery conference, Boston, MA, February 25-27, 2008.
  
  
• “Folate Receptor-targeted Therapies for Cancer and Inflammation”, at the University of Arizona College of Pharmacy, University of Arizona, Tucson, AZ, February 28, 2008.
  
  
• “Folate Receptor-Targeted Therapies for Cancer and Inflammation” at the University of Louisville, Louisville, KY., on March 11, 2008.
  
  
• Invited Speaker at the University of Puerto Rico, Puerto Rico, March 25, 2008, “Folate Receptor-Targeted Therapies for Cancer and Inflammation”


• "Folate Receptor-targeted Delivery of siRNA for Treatment of Cancer and Inflammation", Roche Pharmaceuticals, Lyndhurst NJ, April 1, 2008.
  
  
• "Folate Receptor-targeted Therapies and Imaging Agents for Cancer", Dept. of Oncology, Mayo Clinic, Rochester, MN, April 10, 2008.
  
  
• "Rapid and Accurate Pathogen Identification and Detection", IEEE 2008 International Conference on Technologies for Homeland Security, Waltham, MA, May 12, 2008.
  
  
• "Folate Receptor-targeted Therapies for Cancer and Inflammation", Paul Scherer Institut, Villigen, Switzerland, May 20, 2008.
  
  
• "Folate Receptor-targeted Therapies for Cancer and Inflammation", ETH Zurich, Zurich, Switzerland, May 21, 2008.
  
  
• "Structure and Function of the Red Cell Membrane", "Single Particle Tracking of Protein Diffusion in the Red Cell Membrane", "Structure and Regulation of a Glycolytic Enzyme Complex on the Red Cell Membrane", University of Verona, Verona, Italy, May 23, 24, 2008.
  
  
• "Folate-targeted Liposomal Therapy for Cancer", 2008 NCI/NSTI Cancer Nanotechnology Symposium, Hynes Convention Center, Boston, MA, June 4, 2008.
  
  
• "Ligand-mediated Targeting of siRNAs and Other Therapeutic Agents to Cancer Tissues and Sites of Inflammation", Therapeutic Opportunities of siRNA and Antigomers, New York Academy of Sciences Meeting, Manhattan, NY, June 10, 2008.
  

• Platform presentation: "RNAi Suppression of Motor Proteins in Drosophila Primary Neurons: Dissection of the Axonal Transport of Mitochondria", 47th annual American Society for Cell Biology meetings, Washington, DC, December 4, 2007.

• Presented a lecture on "PGP19 function is regulated by membrane microdomains in Arabidopsis". Eurpoean Plant Endomembrane Meeting, Oxford, U.K., August, 2007.

• Presented a lecture on "APP1 is a rate limiting component of auxin transport and signalling". University of Zurich, September 2007.

• Presented a lecture on "Delaware Membrane Protein Symposium, Centre for Biomedical Research Excellence", Delaware Biotechnology Institute, October 2007.
  
• Murphy AS, Coordinate ABCB and PIN efflux mechanisms function in Arabidopsis auxin transport. McGill University 2007
  
  
• Murphy AS, Regulation of Arabidopsis development by M1 and M24 metalloproteases. University of Wisconsin, Madison, WI Jan 22, 2009
  
  
• Murphy AS, Auxin transport inhibitors target M1 and M24 peptidases in Arabidopsis. IBT-UNAM, Cuernavaca MX 2008
  
  
• Murphy AS, APM1 regulates root development in Arabidopsis. SEB annual meeting, Marseille, FR 2008
  
  
• Murphy AS, APP1 is a rate limiting factor in auxin signalling. SEB annual meeting, Marseille, FR 2008
  
  
• Murphy AS, Auxin transport and phosphorus nutrition. CEA Cadarache, FR 2008
  
  
• Murphy AS, Farewell to NPA sensitivity: a tale of two proteases. Carnegie Institution, Palo Alto, CA 2008
  
  

• Invited seminar. "Probing the functional topography of G protein coupled receptor binding sites" Dept. of Pharmacology and Psychiatry, The Ohio State University Medical Center, March 21, 2008.

Invited Lectures
• "A Niche for Ultrafast Lasers in Protein Structure Determination", Wabash College, Crawfordsville IN, 2009
  
  
• "A Niche for Ultrafast Lasers in Protein Structure Determination", Indiana State University, Terre Haute IN, 2009.
  
  
• "Precise Structural Analysis of Interfaces and Materials by Nonlinear Optical Stokes Ellipsometry" FACSS, Reno NV, 2008.
  
  
• "NLO Properties of Biopolymers and Biopolymer Assemblies" Telluride Research Conference, Telluride CO, 2008.
  
  
• "Organizing and Running a Topical Summer Short Course: What returns can you expect on your investment of time?" Cottrell Scholars Meeting, Tuscon AZ, 2008 (poster).
  
  
• "Molecular Insights from Polarization-Dependent Nonlinear Optical Measurements" Department of Energy Meeting, Annapolis MD, 2008.
  
  
• "Nonlinear Optical Ellipsometry of Chiral Films", International Conference on Organic Nonlinear Optics, Santa Fe NM, 2008.
  
  
• "Improving the Approachability of Introductory Quantum Mechanics Using Wavepacket Dynamics" Chemical Education Seminar, Purdue University, West Lafayette IN, 2008.
  
  
• "The Remarkable Sensitivity of Nonlinear Optics to Chirality" Physical Chemistry seminar, University of California, Los Angeles, 2008.
  
  

Other presentations:
• "Imaging Nonlinear Optical Stokes Ellipsometry: Addressing Spatial and Temporal Bottlenecks Nonlinear Optics" SPIE Photonics West, San Jose, CA, 2009.
  
  
• "Toward a practical protein crystallization microchip" Midwestern Universities Analytical Chemistry Conference, Urbana IL, 2008.
  
  
• "Second order nonlinear optical imaging of chiral crystals (SONICC)" FACSS, Reno NV, 2008.
  
  
• "Microarrays with nonlinear optical readout for rapid screening of protein crystallization conditions" ACS National Meeting, Philadelphia PA, 2008.
  
  

• Invited Symposium Talk, "Regulation of Actin Dynamics in Plants", ComBio 2007, Sydney Australia, September 22-26, 2007.

• "Actin Dynamics in Plant Cells", School of Biological Sciences, University of Newcastle, NSW, Australia, September 28, 2007.

• "Regulation of Actin Dynamics in Plants", Department of Biochemistry and PULSe Plant Biology Seminar Series, Purdue University, October 2, 2007.
  
  
• "Regulation of Actin Dynamics", DOE-Plant Research Laboratory, Michigan State University, December 3, 2007.
  

• Invited Minisymposium talk "Microtubule and Src dynamics in neuronal growth cones during adhesion-mediated guidance", 47th Annual Meeting of the American Society for Cell Biology, Washington, DC, December 1-4, 2007.


• Invited Seminar: "Molecular and cellular mechanisms of adhesion-mediated neuronal growth cone guidance" at Department of Biological Sciences, Purdue University Calumet, Hammond, Indiana, February 22, 2008.


• Invited seminar "Molecular and cellular mechanisms of adhesion-mediated neuronal growth cone guidance", Indiana University Medical School, Stark Neuroscience Research Institute, Indianapolis, Indiana, March 6-7, 2008.


• Invited Seminar: "Molecular and cellular mechanisms of adhesion-mediated neuronal growth cone guidance" at Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN, March 7, 2008.


• Invited seminar "The Neuronal Growth Cone: A sophisticated signaling device". Brain Research Institute, University of Zurich, Zurich Switzerland, August 4, 2008.


• Invited seminar "Integration of sensory, signaling and motile functions in the neuronal growth cone", Department of Biological Sciences, Purdue University, West Lafayette, Indiana, October 22, 2008.


• Invited seminar "Integration of sensory, signaling and motile functions in the neuronal growth cone", Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, Michigan, October 29, 2008.


• Invited seminar "Integration of sensory, signaling and motile functions in the neuronal growth cone", Neuroscience Program, Michigan State University, East Lansing, Michigan, March 19, 2009.

• Departmental Colloquium presented at Polytechnic University, Brooklyn, November 16, 2007.

• Invited Lecture presented at the International Drug Delivery Conference in London, England, December 8-11, 2007.
  
  
• "Design, Synthesis and Performance of Novel Lipids for Templated Protein Crystallization & Membrane Protein Based Biosensing" at City College of New York, Department of Chemical Engineering, March 3, 2008.
  
  
• Keynote Lecture, "Vectorial Transplantation of phi29gp10 Connector Protein into C20BAS Liposome Membranes", Particles 2008, May 10-13, 2008.


• Particles 2008, Orlando, FL, 5/12/08, Keynote Lecture.
  "Strategies for Lipidating and Inserting phi29 into Bilayer Membrane Vesicles"
• Technical University of Denmark, Dept. of Micro & Nanotechnology, Roskilde, Denmark, 7/4/08, Invited Lecture.
  "Development of Bioresponsive Materials for Drug Delivery and Integral Membrane Protein Sensing"


• Tokyo Medical & Dental University, Inst. of Biomaterials & Bioengr., Tokyo, Japan, 7/17/08, Invited Lecture.
  "Design, Synthesis and Performance of Novel Lipids for Templated Protein Crystallization and Membrane Protein-Based Biosensing"
• 11th Liposome Research Days, Yokohama, Japan, 7/21/08, Invited Lecture.
  "Efforts to Develop a High-Throughput Screening Tool Using Isoprenylcarboxyl Methyltransferase-Based Proteoliposomes"
  
  
• GRC: Drug Carriers in Medicine & Biology, Big Sky, MT, 8/25/08, Invited Lecture. "Design and Performance of Bioresponsive Carrier Systems for Drug and Gene Delivery"


• University of Pennsylvania, Dept. of Pharmacology, Philadelphia, PA, 11/12/08, Invited Lecture.
  "Development of Bioresponsive Materials for Drug Delivery"
  
  
• National Cancer Institute, Nanobiology Seminar Series, Bethesda, MD, 1/16/09, Invited Lecture. "Development of Bioresponsive Materials for Site-Selective Drug Delivery and Integral Membrane Protein Sensing"
  
  
• GRC: Drug Carriers in Medicine & Biology, 8/24-29/08, Invited Lecture: "Design & Performance of Bioresponsive Carrier Systems for Drug and Gene Delivery".
  
  
• University of Pennsylvania, Dept. of Pharmacology, 11/12/08, Invited Lecture: "Design & Performance of Bioresponsive Carrier Systems for Drug and Gene Delivery".
  
  
• National Cancer Institute, Nanobiology Seminar Series, 1/16/09, Invited Lecture: "Design & Performance of Bioresponsive Carrier Systems for Drug and Gene Delivery".
  
  
• Thompson, D. H.: "Development of Dynamic Interfaces for Templated Protein Crystallization & Membrane Protein-Based Biosensing", ARO Workshop on Colloids & Surfaces, Napa, CA, March 2009
  
  
• Thompson, D. H.; Holland, D. P.; Febo-Ayala, W.: "Efforts to Develop a High-Throughput Screening Tool Using Isoprenylcarboxyl Methyltransferase-Based Proteoliposomes", International Conference on Nanotechnology, Liposomes and Health, Itaparica, Brazil, April 2009
  
  
• Grey, J. S.; Thompson, D. H.: "Templated Crystallization of His-Proteins Using Dynamic Cyclodextrin:NTA Inclusion Ligand Interfaces", ACS Colloid & Surface Science Symposium, New York, NY, June 2009
  
  
• Hyun, S.-H.; Kim, J.-M.; Thompson, D. H.: "Vectorial Transplantation of phi29 gp10 N-His-Tag Connector Protein Into C20BAS Liposomes", ACS Colloid & Surface Science Symposium, New York, NY, June 2009
  
  

• Co-chair of the session titled "Difficult Structures" at the Annual Meeting of the American Crystallographic Association, May 31 through June 5 2008

• Invited lecture: Oligomerization of carboxyl-terminus regulatory domain of polycystin channels. FASEB summer research conference on Polycystic Kidney Disease: basic, translational and clinical science. July 27-August 1, 2008.