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Event Details

Bioinformatics Seminar

November 13 @ 4:30 PM - 5:30 PM - Lily G126

Date: Tuesday, November 13, 2012
Time: 4:30 PM
Place: LILY G126

Speaker: Paul L. Auer,  Division of Public Health Science, Fred Hutchinson Cancer Research Center, Seattle, WA

Title: "Associating Rare-Genetic Variants with Complex Traits"


Recently there has been a great deal of interest in understanding the role of rare-genetic variation underlying common complex traits. To investigate rare-genetic variation, microarray based Genome Wide Association Studies have been replaced by large scale next-generation sequencing studies. Although these studies produce vastly more fine-scale information on genetic variation, they do so at significant financial, computational, and statistical costs. In this talk I will discuss some of the obstacles we face when analyzing rare-genetic data, some solutions, and a few success stories.

Associated Reading:

Jennifer Asimit and Eleftheria Zeggini. 2012. Rare Variant Association Analysis Methods for Complex Traits  .


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