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Researchers' Guide

Welcome to Purdue University as a principal investigator (PI)!  It is the policy of Purdue University to take every reasonable precaution to provide a work environment that is free from recognized hazards for its employees in accordance with the General Duty clause of the Occupational Health and Safety Administration (OSHA) Act (Public Law 91-596, Section 5(a)(l)).  Our department, Radiological & Environmental Management (REM), is here to help you maintain a safe laboratory and assure compliance with all pertinent regulatory agencies.  REM manages University policies as well as programs and guidelines mandated by Federal and State agencies such as the Occupational Health and Safety Administration (OSHA), Environmental Protection Agency (EPA), National Institutes of Health (NIH), Center for Disease Control and Prevention (CDC)United States Department of Agriculture (USDA), Nuclear Regulatory Commission (NRC), and Indiana State Department of Health (ISDH).  There are specific regulatory issues that apply to functioning of each type of laboratory as well as common "across the board" requirements that cover all laboratories.


REM Web Site Guide

The REM web site is continuously updated and should be your main source for radiological, environmental, and safety information.  It contains extensive information including all necessary documentation and other resources needed to run a compliant and safe laboratory (i.e. policies, forms, postings, templates).  The REM Home Page has an introduction by the REM director that contains a link to the Integrated Safety Plan (ISP); a strategic plan for safety at Purdue that provides a structure to communicate environmental, health and safety issues across the organization.  The Integrated Safety Plan Self Audit Checklist was developed to be used as a guide to determine what aspects of the ISP need to be addressed in your laboratory and/or gauge compliance with the ISP.  In addition to REM assistance, many schools and/or departments may have Safety Committees that can help you with understanding safety and regulatory requirements.

REM Home Page Overview:  Located below the Purdue and REM banners are tabs that provide links to introduction pages for all the REM sections.  Each section's introduction page has buttons along the left margin that link to that section's assigned programs, duties, and responsibilities. Clicking the respective button along the left margin of the REM Home Page will link you to the following content pages described below:

  • The Archives page contains REM newsletters, Annual Safety Chair Presentations, and other news.
  • The Booklets and Guidelines page contains a list of links to documents such as , policies, guidelines, program summaries, and other publications.  These documents can be reviewed in full by clicking on the respective links located on this page.
  • The Contact Us page lists the REM sections and gives a brief description of the sections responsibilities.  Each section's personnel and their telephone numbers are also listed.  Clicking on a staff member's name will direct you to a page with information about their individual responsibilities and an email link.
  • The Don't know Where to go? page can be used if you have no idea which section of REM your questions or concerns should be addressed to.  It contains a list of links to topics that REM has information about or administers.
  • The Forms page contains a list of links to forms and postings that may be needed for your laboratory.  They are listed under the REM section that administers the form.
  • The ISP Information page explqains of the Integrated Safety Plan (ISP) and provides a list of areas that have been certified under ISP.
  • The MSDS Search page has Material Safety Data Sheet (MSDS) links to web sites that have MSDS's available.  A  link to REM's MSDS request form is available as well.
  • The Program Summaries page list the regulated and non-regulated programs and provides a brief description of the programs that REM administers.
  • The Staff Listing page lists REM staff by area and as well as in alphabetically by last name. Click a staff member's name to be directed to their personal information page containing information about their individual responsibilities.
  • The Training page lists training offered by REM under the section that administers it.

The top cell of the table below links to requirements that all researchers must comply with in all research laboratories.  The bottom cell contains additional requirements for laboratories that do the specific types of research and/or have circumstances as listed in the bottom cell.

All research laboratories MUST comply with the following requirements:

Your laboratory MUST comply with the following requirements if research involves any of the following concerns:

Biological Safety

Reference: Biological Safety Manual and Institutional Biosafety Committee Web Site

Laboratory supervisors and principal investigators are responsible for biological safety in the laboratory.  They are also responsible for registering their project with the Institutional Biosafety Committee.  They must ensure that workers know and follow biological safety rules, that personal protective equipment is available and in working order, and that appropriate training has been provided; know the current legal and University requirements concerning biological safety; and ensure that specific training for the use biohazardous agent given.  This program was developed to comply with OSHA, CDC, NIH, and the USDA.  The Biological Safety Program applies to all personnel at Purdue University's West Lafayette Campus and Regional Campuses, University research farms and agricultural centers, and related facilities and operations engaged in the use of biohazardous agents.

Training Requirements:

Documentation Requirements:

Posting Requirements:


Bloodborne Pathogens Safety

Reference: Bloodborne Pathogens Exposure Control Plan

OSHA initiated the Bloodborne Pathogens Standard (29 CFR 1910.1030) in 1992 to eliminate or minimize occupational exposure to bloodborne pathogens (i.e., Hepatitis B Virus, Hepatitis C Virus, Human Immunodeficiency Virus).  Exposures to Bloodborne pathogens can be minimized or eliminated using a combination of engineering and work practice controls, personal protective clothing and equipment, training, medical surveillance, Hepatitis B vaccination, signs and labels, and other provisions.

Training Requirements:

  • Annual bloodborne pathogen training must be within 10 working days of employment.  Contact REM for more information or to schedule an appointment.

Documentation Requirements:

Posting Requirements:


Chemical Safety

Reference: Chemical Hygiene Plan Manual*

The Chemical Hygiene Plan (CHP) was developed by to comply with the OSHA Laboratory Standard (29 CFR 1910.1450) requirement to ensure that the necessary work practices, procedures and policies are implemented to protect laboratory employees from all potentially hazardous chemicals in use in their work area.  The CHP serves as the written document for laboratories using chemicals at Purdue University and applies to all personnel at Purdue University's West Lafayette Campus, Regional Campuses, University research farms, agricultural centers, and related facilities and operations engaged in the laboratory use of hazardous chemicals.

The CHP is a regular, continuing effort, not a standby or short-term activity.  Departments, divisions, sections, or other work units engaged in laboratory work whose hazards are not sufficiently covered in this written CHP manual must customize it by adding their own sections as appropriate (e.g. standard operating procedures, emergency procedures, identifying activities requiring prior approval K).  The CHP also contains several  appendices that will be useful in ensuring compliance with its requirements.  Contact REM for additional information about the CHP.

Training Requirements:

  • Read and follow instructions in the CHP Manual.  Training available upon request from REM's Industrial Hygiene section.

Documentation Requirements:

Posting Requirements:

*The CHP does not apply to the laboratory uses of hazardous chemicals that have no potential for employee exposure or the use of hazardous chemicals which do not meet the definition of laboratory use.  The laboratory uses of chemicals not covered by the CHP are subject to the full provisions of the OSHA Hazard Communication Standard (HazCom) and the Purdue University Right-to-Know Program.


Chemical Waste  Disposal

Reference: Guidelines: Handling and Disposal of Chemicals

The EPA authorized by Resource Conservation and Recovery Act (RCRA) administers the regulations found in Title 40 of the Code of Federal Regulations (40 CFR) to ensure proper identification, handling, storage, and disposal of hazardous waste for protection of human health and the environment.  The Indiana Department of Environmental Management (IDEM) also regulates and administers the hazardous waste compliance program in Indiana.  This combination of federal and state rules, regulations, and procedures govern the management of hazardous waste from the point of generation to the point of final disposition (also known as "Cradle to Grave Management").

It is essential that each individual generating hazardous waste at Purdue University comply with the rules, policies, and procedures stated in the "Guidelines: Handling and Disposal of Chemicals".  The principal investigator has the ultimate responsibility for ensuring their units comply with all environmental, health and safety regulations; and related University policies, procedures, and instructions as given in the Guidelines: Handling and Disposal of Chemicals and provide proper instruction to personnel under their supervision. 

The Guidelines: Handling and Disposal of Chemicals have several figures and tables to help with characterizing, storing and disposing of your hazardous waste.  There is a sample waste pickup form in the "Labels and Forms" section.   Contact REM's Hazardous Materials Management section for more Information.

Training Requirements:

Documentation Requirements:

Posting Requirements:


CONTROLLED SUBSTANCES

Reference: DEA Controlled Substances All individuals utilizing controlled substances for teaching and research must be registered with the Indiana Board of Pharmacy and the Drug Enforcement Administration (DEA).  Appropriate forms and information materials are available online from REM's web site at the link referenced above.

Refer to the above referenced link for program specific registration, documentation, and controlled substance handling requirements.


Human Subjects Laboratories

Reference: Committee on the Use of  Human Research Subjects

The mission of the Committee on the Use of  Human Research Subjects is to protect the privacy, safety, welfare, and rights of human research subjects through a thorough evaluation of recruitment procedures, informed consent processes, and analyses of the risks to the subjects relative to the benefits of the research. Federal, State and University regulations require that the Committee on the Use of Human Research Subjects review all research involving human subjects that is:

  • Sponsored by Purdue University
  • Conducted by or under the direction of any employee or agent of Purdue University in connection with his or her institutional responsibilities
  • Conducted by or under the direction of any employee or agent of Purdue University or using institutional property or assets
  • Facilitated by the use of the institution's non-public information to identify or contact subjects or prospective subjects

Refer to the above referenced web site for program specific training, documentation, and posting requirements.


Laser Laboratories

Reference: Laser Safety Guidelines

Purdue University Laser Safety Committee developed the Laser Safety Guidelines with the purpose of providing individuals using lasers information on laser hazards, laser-related policies and procedures, recommendations for the safe use of lasers, and laser safety training.  It has been designed to provide the basis for safe laser use in the research and teaching environment without placing excessive burdens of cost or use restrictions on those responsible for laser operations.  Much of the information contained is based on the American National Standard Institute (ANSI) for Safe Use of Lasers (ANSI Z136.1-2000) and is the accepted standard for laser safety in the United States.  The Laser Safety Guidelines also contains appendices with tables and forms needed to comply with the Laser Safety Guidelines.  If you need additional information or assistance, contact any member of the Committee, or the REM Laser Safety Officer.

Training Requirements:

  • Read and follow instructions in Laser Safety Guidelines.  Training available upon request from REM's Radiation Safety section.

Documentation Requirements:

Posting Requirements:


Personal Protective Equipment (PPE)
Policy & Hazard Assessment Process

Reference: Personal Protective Equipment (Policy)

The Personal Protective Equipment (PPE) policy implements the requirements of OSHA regulations 29 CFR 1910.132 thru 29 CFR 1910.140.  The policy applies to the use of PPE in all laboratories at the West Lafayette Campus, regional Campuses, University Research Farms and Agricultural Centers, related facilities and operations.  Purdue University policy is that personal protective equipment be provided, used, and maintained in a sanitary and reliable condition.  PPE such as protective clothing, respiratory devices (respirators), shields, and barriers shall be used to protect against chemical, radiological, biological, or mechanical hazards and irritants capable of causing injury or impairment through absorption, inhalation, or physical contact. 

Hazard assessment is the process (required by law) of identifying the hazards associated with a defined task and prescribing personal protective equipment along with other relevant protection measures which must be employed to reduce the risk from the hazards.  The supervisor shall assess each work assignment to determine if hazards are present or likely to be present and require the use of personal protective equipment.  The PPE policy contains appendices with tables, required forms, and the Guidelines For Hazard Assessment and Personal Protective Equipment Selection to help with the hazard assessment process.

Training Requirements:

  • The supervisor shall provide adequate training to each employee who is required to use PPE as per the PPE Policy.

Documentation Requirements:

Posting Requirements:

  • Certification of Hazard Assessment - (PPE Policy, Appendix A1 or A2 or A3* [depending on situation], pages 7-9).


Pesticide Safety
(includes Farms, Forest, Nurseries, and Greenhouses)

Reference: Worker Protection Standard

The EPA through the Title 40, part 170 of the Code of Federal Regulations(40 CFR 170) established the Worker Protection Standard  which pertains to the safety and health of employees who work on farms, in forests, in greenhouses or in nurseries where agricultural use pesticides are used or stored in the production of agricultural plants grown or maintained for commercial or research purposes.  The Worker Protection Standard (WPS) requires agricultural establishment owners such as Purdue University to take steps to reduce the risk of pesticide related illness and injury (1) if they use these pesticides, or (2) employ workers or pesticide handlers who are exposed to such pesticides.  To ensure compliance with the WPS, REM offers Pesticide Handler Training which provides for employees information about exposure to pesticides, protection against exposure to pesticides, and ways to mitigate exposures to pesticides.

Notification of scheduled training sessions is done via e-mail notifications to departmental contacts that distribute and post notifications as necessary.  On campus training for affected departments is provided at the beginning of each semester or on an as "needed basis".  Training for satellite operations and farms is also available upon request.  There is no sign-up required, simply attend any session that suits an individual's schedule.  Contact Judah Young (494-7293 or judah@purdue.edu) for more information or to schedule a training session.

Training Requirements:

  • Worker Protection Standard pesticide safety training sessions are scheduled at the beginning of each semester and can be arranged thorough REM on an as needed basis.

Documentation Requirements:

Posting Requirements:


Radioactive Materials Laboratories

Reference: Radiation Safety Manual

The possession and use of radioactive materials is governed mainly by federal regulations.  The NRC under Title 10 of the Code of Federal Regulations (10 CFR) regulates the use of byproduct material, source and special nuclear material, and reactor operations.  The State of Indiana regulates accelerator produced radioactive material and naturally occurring radioactive material.  Nearly all of the radioactive material used at Purdue University falls under a broad scope license issued by the NRC. This type of license differs from a specific license in that Purdue University is granted the authority and responsibility to set specific conditions of use within the institution. However, these conditions must be compatible with state and federal regulations, representations made to the NRC, and specific license conditions. The broad scope license number is 13-02812-04 and is scheduled for renewal on a five-year basis.

All new uses of radioactive material or radiation-producing devices and major changes in existing authorizations must be approved by the Radiological Control Committee (RCC). Preliminary project review is conducted by REM. Upon recommendation of the RSO, the RCC may grant interim approval of the project. Final approval is granted at quarterly meetings of the RCC.

Training Requirements:

  • Current regulations require that individuals using sources of ionizing radiation have appropriate training prior to the initiation of any work. Basic training in the areas of radiation safety and emergency procedures is provided by REM.
  • The following are the different types of training sessions offered. Please contact REM for the training schedule and to ensure that you attend the appropriate session for your needs.
    • Unsealed radioisotopes (H-3, P-32, S-35, etc.) with the potential for contamination.
    • Sealed sources (Co-60, Cs-137, etc.) with no potential for contamination.
    • Use of the gamma irradiator.
    • Diagnostic x-ray (PUSH, Vet School) use.
    • Analytical x-ray use.
    • Nuclear gauge use and DOT requirements.

Documentation Requirements:

Posting Requirements:


Radioactive Materials Waste Disposal

Reference: Radiation Safety Manual

Refer to the above referenced web safety manual for program specific training, documentation, and posting requirements.

Documentation Requirements:


Respiratory Protection

Reference: Respiratory Protection Program

The purpose of this Respiratory Protection Program is to ensure effective implementation, operation and record-keeping of a University respiratory protection program in compliance with the OSHA Respiratory Protection and Respiratory Protection for M. Tuberculosis standards (29 CFR 1910.134 and 29 CFR 1910.139).  The provisions of the Respiratory Protection Program apply to all personnel at Purdue University's West Lafayette Campus, Regional Campuses, University research farms and agricultural centers, and related facilities and operations.  The primary objective Purdue Respiratory Protection Program shall be to prevent occupational diseases and injuries caused by breathing air contaminated with harmful dusts, fogs, fumes, mists, gases, smokes, sprays, or vapors.  This shall be accomplished, as far as feasible, by accepted engineering control measures (i.e., enclosure or confinement of the operation, general and local ventilation) and substitution of less toxic materials.  When effective engineering controls are not feasible, or while they are being instituted, appropriate respiratory protection shall be used.  Contact the REM Industrial Hygiene section for more information.


Sharps and Infectious Waste Disposal

Reference: Sharps and Infectious Waste: Handling and Disposal Guidelines

This document is for laboratory employees that routinely work with sharps and for building services personnel who are at risk of being punctured or lacerated during their workday.  It is important to properly handle and dispose of this type of waste material in order to prevent injury and potential disease transmission.  REM investigates all improperly disposed sharps and sharp related accidents.  Lab generated biohazardous waste disposal procedures are covered further at this link:Training Requirements:

Documentation Requirements:

Postings Requirements:


Vertebrate Animal Laboratories

Reference: Purdue Animal Care and Use Committee (PACUC) Handbook

The Purdue Animal Care and Use Committee (PACUC) exists to facilitate the performance of productive scientific and scholarly endeavor, involving vertebrate animals. Refer to the above referenced web site for program specific training, documentation, and posting requirements.

Copyright © 2006, Purdue University, all rights reserved.
Last Modified: Monday, June 30, 2008
Send questions or comments about this web site to judah@purdue.edu.

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