Kathleen Hill Gallant

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Educational Background

  • B.S., Dietetics at University of North Dakota, Grand Forks, ND in 2005
  • M.S., Kinesiology at University of North Dakota, Grand Fords, ND in 2006
  • Ph.D., Nutrition at Purdue University, West Lafayette, IN in 2010
  • Postdoctoral training in bone and mineral metabolism at Indiana University School of Medicine, Indianapolis, IN 2010-2013

Certificates & Licenses

  • Certified Dietitian-Indiana Professional Licensing Agency 2009-present
  • Registered Dietitian-Commission on Dietetic Registration 2005-present

Dissertation Title

Predictors of skeletal calcium accretion in adolescents from pooled metabolic balance studies

Awards & Honors

  • American Society for Bone and Mineral Researh Rising Star Award, 2017-2020
  • NIH Mentored Research Scientist Development Award (K01), 2015-2020
  • Women's Global Health Institute Mildred Elizabeth Edmundson Research Grant, 2017
  • Ralph W. and Grace M. Showalter Research Trust Award, 2015
  • Alice L. Jee Memorial Young Investigator Award, International Bone and Mineral Society, 2011
  • Graduate Student Award for Outstanding Teaching, Committee for the Education of Teaching Assistants, Purdue University, 2010
  • Lynn Doctoral Fellowship, Purdue University, 2006 - 2007

Activities & Memberships

  • Faculty Associate, Center on Aging and the Life Course, Purdue University, 2016 - present
  • Member, Nutrition and Dietetic Educators and Preceptors, 2013 - present
  • Member, American Society of Nephrology, 2011 - present
  • Member, American Society for Bone and Mineral Research, 2007 - present
  • Member, American Society for Nutrition, 2007 - present
  • Member, Academy of Nutrition and Dietetics, 2004 - present

Discovery

Chronic kidney disease (CKD) affects approximately 10 % of Americans and 45 % of those over the age of 65 years. Abnormal phosphorus metabolism resulting from loss of kidney function is a critical factor in developing CKD-mineral bone disorder (CKD-MBD), characterized biochemically by an increase in serum fibroblast growth factor-23, parathyroid hormone, and phosphate, and a decreased level of 1,25-dihydroxyvitamin D. Consequences of CKD-MBD include bone disease and fracture, vascular calcification and cardiovascular disease, and ultimately increased mortality. In addition, serum phosphate is positively related to mortality in the non-CKD general population. My research program focuses on elucidating factors that influence and regulate intestinal absorption of dietary phosphorus using human clinical studies and translational research studies in animal models. The goal of this work is to develop strategies to control abnormal phosphorus metabolism and its consequences in CKD patients, as well as in the general population.

Additional research interests include: nutrition for optimal pediatric bone acquisition, and effects of obesity and diabetes on bone mass and quality.

Discovery Publications

  • Hill Gallant KM, Gallant MA, Brown DM, Sato AY, Williams JN, Burr DB. (2014) Raloxifene prevents skeletal fragility in adult female Zucker Diabetic Sprague-Dawley Rats. PLoS One. 9(9):e108262. PMID: 25243714.
  • Berger P, Pollock N, Laine EM, Warden SJ, Hill Gallant KM, Hausman DB, Tipp R, McCabe LD, McCabe GP, Weaver CM, Peacock M, Lewis RD. (2014) Association of adenovirus 36 infection with adiposity and inflammotry-related markers in children. J Clin Endocrinol Metab.:epub ahead of print. PMID: 24926952.
  • Hill, K.M., Martin, B.R., Wastney, M.E., McCabe, G.P., Moe, S.M., Weaver, C.M., Peacock, M. (2013) Oral calcium carbonate affects calcium but not phosphorus balance in stage 3-4 chronic kidney disease. Kidney Int. 83:959-66. PMID: 23254903.
  • Lewis RD, Laing EM, Hill Gallant KM, Hall DB, McCabe GP, Hausman DB, Martin BR, Warden SJ, Peacock M, Weaver CM.. (2013) A randomized trial of vitamin D3 supplementation in children: dose-response effects on vitamin D metabolites and calcium absorption. J Clin Endocrinol Metab. 98(12):4816-25.
  • Warden, S.J., Hill, K.M., Ferira, A.J., Laing, E.M., Martin, B.R., Hausman, D.B., Weaver, C.M., Peacock, M., Lewis, R.D. (2013) Racial differences in cortical bone and their relationship to biochemical variables in black and white children in the early stages of puberty. Osteoporosis Int. 24(6):1869-79. PMID: 23093348.
  • Hill, K.M., Laing, E.M., Hausman, D.B., Acton, A., Martin, B.R., McCabe, G.P., Weaver, C.M., Lewis, R.D., and Peacock, M. (2012) Bone turnover is not influenced by serum 25-hydroxyvitamin D in pubertal healthy black and white children. Bone. 51(595)
  • Grethen, E., Hill, K.M., Jones, R., Cacucci, B.M., Grupta, C.E., Acton, A., Considine, R., Peacock, M. (2012) Serum leptin, parathyroid hormone, 1,25-dihydroxyvitamin D, fibroblast growth factor 23, bone alkaline phophates, sclerostin relationships in obesity. J Clin Endocinol Metab. 97:1655-62. PMID: 22362819.
  • Hill, K.M., Jonnalagadda, S.S., Albertson, A.M., Josh NA, and Weaver C.M. (2012) Top Food Sources Contributing to Vitamin D Intake and the Association of Ready-to-Eat Cereal and Breakfast Consumption Habits to Vitamin D Intake in Canadians and United States Americans. J Food Sci. 77:H170-H175.
  • Elble, A.E., Hill, K.M., Park, C.Y., Martin, B.R., Peacock, M., and Weaver, C.M. (2011) Effect of calcium carbonate particle size on absorption and retention in adolescent girls. J Am Col Nutr. 30(3):171-7. PMID: 21896874.
  • Hill, K.M., Braun, M.M., Egan, K.A., Martin, B.R., McCabe, L.D., Peacock, M., McCabe, G.P., and Weaver, C.M. (2011) Obesity augments calcium-induced increases in skeletal calcium retention in adolescents. J Clin Endocrinol Metab. 96(7):2171-77. PMID: 21490075.
  • Hill, K.M., Whitehead, J.R., Goodwin, J.K. (2011) Pre-workout carbohydrate supplementation does not affect measures of self-assessed vitality and affect in college swimmers. J Sports Sci Med. 10:478-82.
  • Park, C.Y., Hill, K.M., Elble, A.E., Martin, B.R., DiMeglio, L.A., Peacock, M., McCabe, G.P., Weaver, C.M. (2010) Daily supplementation with 25 µg cholecalciferol does not increase calcium absorption or skeletal retention in adolescent girls with low serum 25-hydroxyvitamin D. J Nutr. 140(12):2139-44. PMID: 20962148.
  • Hill, K.M., McCabe, G.P., McCabe, L.D., Gordon, C.M., Abrams, S.A., Weaver, C.M. (2010) An inflection point of serum 25-hydroxyvitamin D for maximal suppression of parathyroid hormone is not evident from multi-state pooled data in children and adolescents. J Nutr. 140(11):1983-1988. PMID: 20861214.
  • Hill, K.M., Braun, M., Kern, M., Martin, B.R., Navalta, J.W., Sedlock, D.A., McCabe L., McCabe, G.P., Peacock, M., Weaver, C.M. (2008) Predictors of calcium retention in adolescent boys. J Clin Endocinol Metab. 93(12):4743-4748. PMID: 18840643.

Books, Chapters & Monograph Publications

  • Weaver, C.M., Hill Gallant, K.M., . (2014) Nutrition. In: Basic and Applied Bone Biology. Burr, D.B., Allen, M.R. Ed(s). Ch.Chapters. Pp.Pages. Academic Press/Elsevier, Waltham, MA. ISBN: 978-0-12-416015-6.
  • Bellido, T., Hill Gallant, K.M. (2014) Hormonal Effects on Bone Cells. In: Basic and Applied Bone Biology. Burr, D.B., Allen, M.R. Ed(s). Ch.Chapters. Pp.Pages. Academic Press/Elsevier, Waltham, MA. ISBN: 978-0-12-416015-6.
  • Weaver, C.M., Hill, K.M. (2013) Osteoporosis: The Early Years. In: Nutrition in the Prevention and Treatment of Disease, 3rd edition. Coulston, A.M., Boushey, C.J., Ferruzzi, M.G. Ed(s). Ch.Chapters. Pp.Pages. Academic Press/Elsevier, Waltham, MA. DOI: 10.1016/B978-0-12-391884-0.00044-5.
  • Weaver, C.M., Hill, K.M. (2010) Estimating Calcium Requirements. In: Nutritional Influences on Bone Health. Burckhardt, P., Dawson-Hughes, B., Weaver, C.M. Ed(s). Ch.Chapters. Pp.41-49. Springer-Verlag, London, UK. DOI: 10.1007/978-1-84882-978-7_6.

Learning

NUTR 480 Medical Nutrition Therapy I
NUTR 481 Medical Nutrition Therapy II
NUTR 590 Basic Bone Biology
NUTR 590 Women's Health: Bone

Kathleen Hill Gallant

Assistant Professor & Director, Didactic Program in Dietetics
Adjunct Assistant Professor of Medicine, Indiana University School of Medicine
Faculty Associate:
    Center on Aging and the Life Course

Office: STON 207
Phone: 765.494.0101
Fax: 765.494.0674
E-Mail: hillgallant@purdue.edu

Department of Nutrition Science, 700 W. State Street, West Lafayette, IN 47907-2059(765) 494-8228, Fax: (765) 494-0674

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