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Sean Newcomer

Sean Newcomer

Assistant Professor

Education:Postdoctoral Research Fellow (2007), University of Missouri, Columbia
Ph.D. (2004), Pennsylvania State University, University Park, PA
M.S. (1996), Humboldt State University, Arcata, CA
B.S. (1994), University of Oregon, Eugene
 
Office:LAMB 008A
Office Phone:(765) 49-62612
Office Fax:(765) 49-61239
Email:
snewcome@purdue.edu
 
 
Specializations:

Exercise Physiology
mechanisms underlying limb differences in vascular function, atherogenesis, and the response to exercise

 
Courses:HK 468 - Advanced Exercise Physiology
HK 668 - Seminar in Exercise Physiology

Academic Appointments:

  • Assistant Professor, Department of Health and Kinesiology, Purdue University, West Lafayette, IN (2008-present)

Research Interests:

Dr. Newcomer’s research focuses on the mechanisms underlying limb differences in vascular function, atherogenesis, and the response to exercise in humans.

Memberships in Professional Organizations:

  • American Physiological Society
  • American Heart Association
  • American College of Sports Medicine

Recent Publications:

  • Newcomer, S.C., Taylor, J.C., McAllister, R.M and Laughlin, M.H. Effects of Chronic Nitric Oxide Synthase Inhibition on Endothelium-Dependent and -Independent Relaxation in Swine Forelimb and Hindlimb Vasculatures. Endothelium. Jan-Apr; 15(1-2):17-31, 2008.
  • Newcomer, S.C., Sauder, C.L., Kuipers, N.T., Laughlin, M.H. and Ray, C.A. Effects of posture on shear rates in human brachial and superficial femoral arteries.  American Journal of Physiology (Heart and Circulatory Physiology).  Apr; 294(4): H1833-9, 2008.
  • Laughlin, M.H., Newcomer, S.C. and Bender, S.B. Importance of hemodynamic signals for exercise-induced changes in endothelial cell phenotype. Journal of Applied Physiology.  Mar; 104(3): 588-600, 2008.
  • McAllister, R.M., Newcomer, S.C., Pope, E.R. Turk, J.R. and Laughlin, M.H. Effects of chronic nitric oxide synthase inhibition on responses to acute exercise in swine. Journal of Applied Physiology. Jan; 104(1):186-97, 2008
  • McAllister, R.M., Newcomer, S.C., and Laughlin M.H.  Vascular nitric oxide: effects of exercise training. Applied Physiology, Nutrition, and Metabolism. Jan; 33: 173-178, 2008.
  • Reifenberger, M.S., Turk, J.R., Newcomer, S.C., Booth, F.W. and Laughlin, M.H. Pervascular fat alters reactivity of coronary artery: effects of diet and exercise. Medicine and Science in Sports and Exercise. Dec; 39(12): 2125-34, 2007.
  • Newcomer, S.C., Taylor, J.C., Bowles, D.K. and Laughlin, M.H.  Endothelium-dependent and -independent relaxation in the forelimb and hindlimb vasculature of swine. Comparative Biochemistry and Physiology. Oct; 148(2):292-300, 2007.
  • Ingram, D.G., Newcomer, S.C., Price, E, Eklund, K, McAllister, R, and Laughlin, M.H.  Chronic nitric oxide synthase inhibition blunts endothelium-dependent function of conduit coronary arteries, not arterioles Author list: American Journal of Physiology (Heart and Circulatory Physiology). June; 293(6): H2798-808, 2007.
  • Proctor, D.N. and Newcomer, S.C.  Is there a difference in vascular reactivity of the arms and legs?  Medicine and Science in Sports and Exercise. October; 38(10): 1819-1828, 2006.
  • Koch, D.W., Newcomer, S.C., and Proctor, D.N. Blood flow to exercising limbs varies with age and sex.  Canadian Journal of Applied Physiology.  October; 30(5):554-575, 2005.
  • Newcomer, S.C., Leuenberger, U.A., Hogeman, C.S., and Proctor, D.N. Heterogeneous vasodilator responses of human limbs: influence of age and habitual endurance training. American Journal of Physiology (Heart and Circulatory Physiology).   July; 289(1):H308-H315, 2005.
  • Newcomer, S.C., Hogeman, C.S., Handly, B.D., Leuenberger, U.A., and Proctor, D.N.  Different vasodilator responses of human arms and legs. Journal of Physiology. May; 556(3):1001-1011, 2004.
  • Proctor, D.N., Koch, D.W., Newcomer, S.C., Le, K.U., Smithmyer, S.L., and Leuenberger, U.A.  Leg blood flow and VO2 during peak cycle exercise in younger and older women.  Medicine and Science in Sports and Exercise. April; 36(4):623-631, 2004.
  • Proctor, D.N., Koch, D.W., Newcomer, S.C., Le, K.U., and Leuenberger, U.A.  Impaired leg vasodilation during dynamic exercise in healthy older women.  Journal of Applied Physiology. July; 95:1963-70, 2003.
  • Proctor, D., Newcomer, S., Koch, D. Le, K., Maclean, D., and Leuenberger, U.  Leg blood flow during submaximal cycle ergometry is not reduced in healthy older normally active men. Journal of Applied Physiology. May; 94(5):1859-69, 2003.
  • Richardson, R.S., Newcomer, S.C., and Noyszewski E.A.  Skeletal muscle intracellular PO2 assessed by myoglobin desaturation: response to graded exercise.  Journal of Applied Physiology. Dec; 91(6):2679-2685, 2001.

Awards:

  • NIH (National Institute on Aging/National Heart Lung and Blood Institute) Predoctoral Fellow
  • NIH (National Institute on Aging/National Heart Lung and Blood Institute) Postdoctoral Fellow
  • American Physiological Society's Caroline tum Suden/Frances Hellebrandt Professional Opportunity Award

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