Control of eukaryotic gene expression and replication; DNA structure; virus evolution
Mechanism(s) of liver cancer pathogenesis by the Hepatitis B Virus X protein. Signal transduction networks in neuronal development and cancer pathogenesis.
Role of histone methylation in gene expression and oncogenesis
Transcriptional regulation in poxviruses
Reproductive physiology and molecular biology
Nutritional Biochemistry and Physiology
Chromatin Remodeling and Cancer
Regulation of mineral metabolism, molecular actions of vitamin D in calcium metabolism and cancer prevention, gene-environment interactions influencing bone/calcium metabolism or cancer
Mechanism of the transfer to and expression of the Agrobacterium tumefaciens Ti-plasmid in plant cells
Regulation of DNA methylation in development and disease
Macronutrients, exercise and mitochondria
Molecular biology, cell biology, cancer biology and molecular imaging
Single molecule fluorescence lifetime imaging and fluorescence correlation spectroscopic measurements of epigenetic modification of single living cells, Nanotools and Raman spectroscopy for detecting in vivo phosphorylation, mRNA, and Micro RNA.
DNA microarray technology to investigate the genomic basis of disease, development, and drug toxicity
Biological roles of miRNAs and their use as cancer therapeutics
Epigenetic processes that mediate heritable modifications to chromatin
Gene expression during mammalian development; cancer model systems
Understanding how the cell nucleus directs expression and stability of the genome and how tissue architecture influences nuclear organization; development of 3D cell culture and organ-on-a-chip models for discovery of targets and cell nucleus-based readouts in cancer prevention and treatment;
Epigenetic regulation of transposable elements
Regulation of cell identity, signal transduction, chromatin remodeling
Nutritional Epigenetics, Cancer Epigenetics. Epigenetic mechanisms of vitamins and polyphenols in cancer prevention and therapy. Epigenetic biomarkers for solid tumors.
Oncogene expression in eukaryotic cells
Defining the Molecular Basis for p68 (Dbp2) in Gene Expression and Cellular Proliferation
Chromatin modifying complexes in Drosophila development as a model for neurodegenerative disease and cancer
Maize genetics, genomics, value-added traits
Signal transduction in cancer biology, early neuronal development and cancer metabolism.