Standard Operating Procedures

The OSHA Laboratory Standard (i.e. Chemical Hygiene Plan) requires SOPs relevant to safety and health considerations to be prepared and followed when laboratory work involves the use of hazardous chemicals. Other regulatory programs may also require SOPs.

Standard operating procedures (SOPs) are written instructions that detail the steps taken to perform a given operation and include information about potential hazards and how the hazards will be mitigated. It is prudent to have SOPs for work involving chemical, biological, animal, and radiological hazards; radiation producing devices; and other physical hazards. SOPs should be written by personnel who are most knowledgeable with the experimental process and associated hazards. However, the Laboratory Supervisor is ultimately responsible for approving SOPs regardless of who prepared them.

The SOP templates available below have been prepared by REM using templates developed by the University of California (Los Angeles) Environmental Health and Safety Department. These templates are for common and hazardous operations. They are incomplete as written; they must be customized. Instructions for completion are included in each template. The templates are part of an ongoing effort by REM to provide SOP guidance. Our template list will continue to grow to incorporate more hazards. Laboratories, shops, and other areas with hazardous operations are encouraged to develop their own SOPs using this template format.

Contact REM at (765) 496-3072 if you need assistance or would like to submit a SOP to be considered for making into a template and posting below.

Chemicals Requiring SOPs:

  1. Acutely Toxic Materials
  2. Alkali Metals
  3. Animal Research High Hazards
  4. Ammonia
  5. Aqua Regia
  6. Base Bath
  7. Benzene
  8. Biosafety Level 2
  9. Boron Tribromide
  10. Boron Trichloride
  11. Boron Trifluoride
  12. Bromine
  13. Chloroform
  14. Chlorine Gas
  15. Chromerge (Chromic acid solution)
  16. Compressed Gases
  17. Corrosives
  18. Dangerous When Wet Materials
  19. Diethyl Ether
  20. Ethidium Bromide
  21. Ethylene Oxide
  22. Flammable and Combustible Liquids
  23. Flammable  Solids
  24. Formaldehyde
  25. Hydrogen Fluoride (HF)
  26. Hydrogen Gas
  27. Hydrogen Peroxide
  28. Hydrogen Sulfide
  29. Isophorone Diisocyanate
  30. Liquid Nitrogen
  31. Lithium Alkyl Compounds
  32. Lithium Metal
  33. Mercury
  34. Methylene Chloride (Dichloromethane)
  35. Methyltrichlorosilane
  36. Nitrate Salts
  37. Nitric Acid
  38. Nitric Oxide
  39. Osmium Tetroxide
  40. Oxidizers
  41. Peracetic Acid (Peroxyacetic Acid)
  42. Perchloric Acid
  43. Perfluorodecyltrichlorosilane
  44. Piranha Solution
  45. Potassium Cyanide
  46. Propylene Oxide
  47. Pyrophorics
  48. Sodium Azide
  49. Sulfuric Acid
  50. Zirconium Powder