Standard Operating Procedures (SOPs)

The OSHA Laboratory Standard requires standard operating procedures (SOPs) relevant to safety and health considerations to be prepared and followed when laboratory work involves the use of hazardous chemicals. SOPs are written instructions that detail the steps that will be performed during a given procedure and include information about potential hazards and how these hazards will be mitigated. SOPs should be written by laboratory personnel who are most knowledgeable and involved with the experimental process. However, the laboratory manager (Principal Investigator) is ultimately responsible for approving SOPs regardless of who prepared them.

The SOPs templates available below have been prepared by REM and developed for commonly used laboratory chemicals (e.g., flammable and combustible liquids, formaldehyde) and high-hazard chemicals (HF, alkyl lithium compounds). These SOPs are not complete as is; they are templates that must be customized by each laboratory before they are considered complete. Instructions for completion are included in each SOP template. Once customized, the SOPs should be added to the lab’s Chemical Hygiene Plan. This list of SOPs below is an ongoing effort by REM to provide SOP guidance and the list will continue to grow. However, laboratories are encouraged to develop their own SOPs using this template format. These SOPs have been prepared using templates developed by the University of California – Los Angeles Environmental Health and Safety Department.

Contact REM at (765) 496-3072 if you need assistance or would like to submit a SOP to be considered for making into a template and posting below.

Chemicals Requiring SOPs:

  1. Acutely Toxic Materials
  2. Alkali Metals
  3. Animal Research High Hazards
  4. Aqua Regia
  5. Base Bath
  6. Benzene
  7. Biosafety Level 2
  8. Bromine
  9. Chloroform
  10. Chromerge (Chromic acid solution)
  11. Compressed Gases
  12. Corrosives
  13. Dangerous When Wet Materials
  14. Diethyl Ether
  15. Ethidium Bromide
  16. Ethylene Oxide
  17. Flammable and Combustible Liquids
  18. Flammable  Solids
  19. Formaldehyde
  20. Hydrogen Fluoride (HF)
  21. Hydrogen Peroxide
  22. Liquid Nitrogen
  23. Lithium Alkyl Compounds
  24. Mercury
  25. Methylene Chloride (Dichloromethane)
  26. Methyltrichlorosilane
  27. Nitrate Salts
  28. Nitric Acid
  29. Osmium Tetroxide
  30. Oxidizers
  31. Perfluorodecyltrichlorosilane
  32. Piranha Solution
  33. Potassium Cyanide
  34. Propylene Oxide
  35. Pyrophorics
  36. Sodium Azide
  37. Sulfuric Acid
  38. Zirconium Powder