Standard Operating Procedures (SOPs)

The OSHA Laboratory Standard requires standard operating procedures (SOPs) relevant to safety and health considerations to be prepared and followed when laboratory work involves the use of hazardous chemicals. SOPs are written instructions that detail the steps that will be performed during a given procedure and include information about potential hazards and how these hazards will be mitigated. SOPs should be written by laboratory personnel who are most knowledgeable and involved with the experimental process. However, the laboratory manager (Principal Investigator) is ultimately responsible for approving SOPs regardless of who prepared them.

The SOPs templates available below have been prepared by REM and developed for commonly used laboratory chemicals (e.g., flammable and combustible liquids, formaldehyde) and high-hazard chemicals (HF, alkyl lithium compounds). These SOPs are not complete as is; they are templates that must be customized by each laboratory before they are considered complete. Instructions for completion are included in each SOP template. Once customized, the SOPs should be added to the lab’s Chemical Hygiene Plan. This list of SOPs below is an ongoing effort by REM to provide SOP guidance and the list will continue to grow. However, laboratories are encouraged to develop their own SOPs using this template format. These SOPs have been prepared using templates developed by the University of California – Los Angeles Environmental Health and Safety Department.

Contact REM at (765) 496-3072 if you need assistance or would like to submit a SOP to be considered for making into a template and posting below.

Chemicals Requiring SOPs:

  1. Acutely Toxic Materials
  2. Alkali Metals
  3. Animal Research High Hazards
  4. Ammonia
  5. Aqua Regia
  6. Base Bath
  7. Benzene
  8. Biosafety Level 2
  9. Boron Tribromide
  10. Boron Trichloride
  11. Boron Trifluoride
  12. Bromine
  13. Chloroform
  14. Chlorine Gas
  15. Chromerge (Chromic acid solution)
  16. Compressed Gases
  17. Corrosives
  18. Dangerous When Wet Materials
  19. Diethyl Ether
  20. Ethidium Bromide
  21. Ethylene Oxide
  22. Flammable and Combustible Liquids
  23. Flammable  Solids
  24. Formaldehyde
  25. Hydrogen Fluoride (HF)
  26. Hydrogen Gas
  27. Hydrogen Peroxide
  28. Hydrogen Sulfide
  29. Liquid Nitrogen
  30. Lithium Alkyl Compounds
  31. Lithium Metal
  32. Mercury
  33. Methylene Chloride (Dichloromethane)
  34. Methyltrichlorosilane
  35. Nitrate Salts
  36. Nitric Acid
  37. Nitric Oxide
  38. Osmium Tetroxide
  39. Oxidizers
  40. Peracetic Acid (Peroxyacetic Acid)
  41. Perfluorodecyltrichlorosilane
  42. Piranha Solution
  43. Potassium Cyanide
  44. Propylene Oxide
  45. Pyrophorics
  46. Sodium Azide
  47. Sulfuric Acid
  48. Zirconium Powder