Standard Operating Procedures

The OSHA Laboratory Standard (i.e. Chemical Hygiene Plan) requires SOPs relevant to safety and health considerations to be prepared and followed when laboratory work involves the use of hazardous chemicals. Other regulatory programs may also require SOPs.

Standard operating procedures (SOPs) are written instructions that detail the steps taken to perform a given operation and include information about potential hazards and how the hazards will be mitigated. It is prudent to have SOPs for work involving chemical, biological, animal, and radiological hazards; radiation producing devices; and other physical hazards. SOPs should be written by personnel who are most knowledgeable with the experimental process and associated hazards. However, the Laboratory Supervisor is ultimately responsible for approving SOPs regardless of who prepared them.

The SOP templates available below have been prepared by REM using templates developed by the University of California (Los Angeles) Environmental Health and Safety Department. These templates are for common and hazardous operations. They are incomplete as written; they must be customized. Instructions for completion are included in each template. The templates are part of an ongoing effort by REM to provide SOP guidance. Our template list will continue to grow to incorporate more hazards. Laboratories, shops, and other areas with hazardous operations are encouraged to develop their own SOPs using this template format.

Contact REM at (765) 496-3072 if you need assistance or would like to submit a SOP to be considered for making into a template and posting below.

Chemicals Requiring SOPs:

  1. Acrolein (2-Propenal)
  2. Acutely Toxic Materials
  3. Alkali Metals
  4. Animal Research High Hazards
  5. Ammonia
  6. Aqua Regia
  7. Base Bath
  8. Benzene
  9. Biosafety Level 2
  10. Boron Tribromide
  11. Boron Trichloride
  12. Boron Trifluoride
  13. Bromine
  14. Chloroform
  15. Chlorine Gas
  16. Chromerge (Chromic acid solution)
  17. Compressed Gases
  18. Corrosives
  19. Dangerous When Wet Materials
  20. Diethyl Ether
  21. Ethidium Bromide
  22. Ethylene Oxide
  23. Flammable and Combustible Liquids
  24. Flammable  Solids
  25. Formaldehyde
  26. Hydrogen Fluoride (HF)
  27. Hydrogen Gas
  28. Hydrogen Peroxide
  29. Hydrogen Sulfide
  30. Isophorone Diisocyanate
  31. Liquid Nitrogen
  32. Lithium Alkyl Compounds
  33. Lithium Metal
  34. Mercury
  35. Methylene Chloride (Dichloromethane)
  36. Methyltrichlorosilane
  37. Nitrate Salts
  38. Nitric Acid
  39. Nitric Oxide
  40. Osmium Tetroxide
  41. Oxidizers
  42. Peracetic Acid (Peroxyacetic Acid)
  43. Perchloric Acid
  44. Perfluorodecyltrichlorosilane
  45. Piranha Solution
  46. Potassium Cyanide
  47. Propylene Oxide
  48. Pyrophorics
  49. Sodium Azide
  50. Sulfuric Acid
  51. Zirconium Powder