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“Our theme is multiplex mechanistic sensing and quantification of molecular markers, genetic material, and drugs in biological systems using SERS, nanomaterials, and single molecule studies. While doing so, we cherish the moments that are joyous and try to forget those that are painful”
Dr. Irudayaraj's focus is to develop nanotools and single molecule methods relevant to elucidation of intracellular mechanisms and realtime diagnostics for early detection of diseases or prognosis. Single molecule methods as tools for understanding, asking, and answering fundamental biological questions, for example receptor oligomerization, cell surface kinetics, drug diffusion, are at the heart of our research. Single particle optical methods and nanofabrication for multiplex probing of single cell molecular markers, quantification of genetic variants, and dynamic chemical imaging of cellular events perk our interest.
The basis for Dr. Irudayaraj's work stems from a strong background and skills developed in the areas of biospectroscopy, biosensors, and numerical modeling. Dr. Irudayaraj is also a Co-Director of the Physiological Sensing Facility (PSF) and a member of the Biophysics Core at Bindley and has authored over 150 refereed publications. Prior to Purdue, Dr. Irudayaraj was an Associate Professor at The Pennsylvania State University (1998-2004) and a visiting faculty (2004-2005) at the School of Applied and Engineering Physics at Cornell University.
Our Imaging lab is housed at the Bindley Bioscience Center and synthesis and instrumentation facilities are spread out between ABE and PSF laboratories. We represent the Bionanotechnology efforts of the Birck Nanotechnology Center and are affiliated with Purdue Cancer Center and the Oncological Sciences Center.
Students, visiting scholars, and faculty with research and collaborative interests are encouraged to contact Dr. Irudayaraj at josephi@purdue.edu [765-494-0388]
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