Research Core Technologies
Technologies and expertise necessary for probing biological systems are
aggregated into discrete research cores at Bindley Bioscience Center (BBC).
These Cores are geared toward development of innovative methods and tools,
organization of faculty expertise, and provision of unique state-of-art services
to the research community. The overall functional integration of these different
capabilities is designed to meet the scientific and technical challenges
across bioscience disciplines and approaches. Working collaboratively with
the academic units to support and coordinate the activities of these research
cores, a host of BBC-affiliated Purdue researchers developed
relevant core facilities, evaluated their capabilities, and acquired instrumentation
and expertise that was not formerly available to Purdue researchers.
Core infrastructure and facilities are housed in the Bindley Bioscience Center building; however, many are distributed around other West Lafayette campus locations. The Research Cores are staffed by experienced investigators, many of whom will have appointments in the Research Professorial ranks. Core technologies and applications that support the research themes of the Bindley Bioscience Center are under continual development. At present they include:
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Access to the Research Cores of the Bindley Bioscience Center is available to researchers whose projects require biomolecular analyses. The Cores are integrated and accessible at any level of involvement that is appropriate, from research collaborations to fee-for-service analyses. State-of-the-art instrumentation is available for proteomic, metabolomic, and genomic analyses. For more information-CLICK HERE
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Opportunities to advance bioscience research with technology development at the atomic and molecular scale are increasingly recognized, particularly in pursuit of new diagnostics and therapeutics. This core takes advantage of Purdue strengths in micro and nano-scale engineering and the capacity of remarkable new Birck Nanotechnology Center to focus on nanomedicine. Approaches range from microfluidic 'lab-on-a-chip' detection systems to biosensor development and application to biopolymers for nanofabrication and detection schemes to innovative optic/photonic methods for biomarker discovery and characterization. For more information-CLICK HERE
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Infrastructure and informatics tool development for ultrasensitive and high throughput analysis of complex biological mixtures is achieved with active leveraging of the substantial resources in this area at Purdue and Discovery Park. Unique solutions in development include vendor-independent data formats from analytical instruments and active interfacing to instrumentation for real-time control of instrument data acquisition. For more information-CLICK HERE
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Cytomics aims to position proteomic and genomic information in the
cellular context (the cytome). A major goal of this core is provide
the links from molecules to function at the cellular level. Approaches
include novel multispectral cellular and subcellular imaging techniques
and instrumentation and algorithm development to improve sensitivity
and throughput of cytometric and imaging techniques. Innovative methods
for correlation of cytomics / imaging data with proteomic / metabolomic
data are also in development. For more information-CLICK
HERE
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