Specific Projects

 

RESEARCH PROGRAMS UNDERWAY

  • Biomedical
    • Detection of in vivo phophorylation using surface enhanced Raman spectroscopy (SERS). Irudayaraj and Parker (Medicinal Chemistry and Molecular Pharmacology)
    • In vivo detection of double DNA breaks in living cells. Irudayaraj and Lelievre (BMS)
    • Reverse Electrokinetic Pattering in biology: Motility studies, Chorum sensing, and cell sorting. Steve Worley (ME) and Irudayaraj.
    • Epigenetics Research
      • In vivo epigenetics tools development. Irudayaraj, Kirchmaier (BCHM), Lossie (Animal Sciences).
      • Single molecule tools for examining histone modifications in living cells. Kirchmaier (Biochemistry) and Irudayaraj.
      • Quantification of epigenetic modifications in 3D tissue culture models. Lelievre (BMS) and Irudayaraj
    • In vivo detection mRNA and microRNA in single cells and tissues by plasmon imaging. Irudayaraj, Badve (Clarion IU School of Medicine) and Kirchmaier (BCMH)
    • Indo-US Center for Cellular Engineering for biomedical research. Irudayaraj and Rao, CCMB (Hyderabad, India) [Dr. Irudayaraj and Rao are Co-directors]
  • Environment
    • Bioremediation: Mapping chromate/Arsenate reduction sites in single bacterium by SERS. Irudayaraj, Nakatsu (AGRY), and Thompson (Biological Sciences, University of Tennessee)
    • Detection of rare splice variants in plants using Confocal Raman Spectroscopy. Irudayaraj and Schulz (HLA)
    • Pathogen detection spectroscopic biosensors. Irudayaraj and Mauer (Food Science)
  • Instrumentation
    • Development of a hyperspectral plasmon scanning workstation. Irudayaraj
    • Major research instrumentation for the development of high speed Raman instrumentation. Ben-Amotz (Chemistry) and Irudayaraj.
    • Probe-based single molecule fluorescence correlation spectroscopy. Maiti (TIFR, India) and Irudayaraj
    • Major research instrumentation for the acquisition of multiphoton laser for ultrafast dynamics. Lucht (Mechanical Engineering), Irudayaraj, and 3 other Co-PIs.
    • Development of a label-free single molecule platform for imaging structures in single cells. Irudayaraj.
  • International Projects
    • Indo-US Center for Cellular Engineering for biomedical research. Irudayaraj and Rao, CCMB (Hyderabad, India)
    • Tumor ablation enhanced by nanorods using radio frequency. Irudayaraj and Ganesh (MG Ramachandra Medical College, Chennai, India)
    • Korean Institute of Science and Technology (KIST) on Nanomedicine

*[MCMP: Medicinal Chemistry and Molecular Pharmacology; BCHM: Biochemistry; BMS: Basic Medical Chemistry; HLA: Horticulture and Landscape Architecture; ME: Mechanical Engineering; AGRY: Agronomy; TIFR: Tata Institute of Fundamental Sciences; CCMB: Center for Cellular and Molecular Biology]

 

 
 
 
 
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