Purdue researchers apply new technique to manipulate virus, make it a possible cancer treatment
November 27, 2013
WEST LAFAYETTE, Ind. — Purdue University researchers successfully eliminated the native infection preferences of a Sindbis virus engineered to target and kill cancer cells, a milestone in the manipulation of this promising viral vector.
"This virus had been known to be a good vector for delivering therapeutic cargo, however it naturally infected all kinds of cells, and these diversions would compete with what we were instructing it to target," said Richard Kuhn, the Gerald and Edna Mann Director of Purdue's Bindley Biosciences Center. "We have now overcome a major challenge by not only inserting a targeting molecule of our choice, but also successfully stripping the virus of its native entry preferences. This was a big step in unlocking the potential of developing this virus into a platform for both targeted drug delivery, where it would sneak drugs inside cancer cells, and oncolytic virotherapy, where the virus itself destroys cancer cells."
- Elizabeth K. Gardner, Writer
July 25, 2014
A Purdue Research Park-based company whose one-step, patent-pending technology could improve the efficiency of alternative fuels and the production of fragrance products has received funding from the National Science Foundation. Spero Energy Inc. has received a six-month SBIR Phase I grant from the NSF worth $150,000. Its technology is based on Purdue University intellectual property.Read Full Story
July 25, 2014
Spinach gave Popeye super strength, but it also holds the promise of a different power for a group of scientists: the ability to convert sunlight into a clean, efficient alternative fuel. Purdue University physicists are part of an international group using spinach to study the proteins involved in photosynthesis, the process by which plants convert the sun’s energy into carbohydrates used to power cellular processes.Read Full Story
July 14, 2014
A group of Russian undergraduate students will spend a month of their summer at Purdue University and the Purdue Research Park to expand their knowledge of entrepreneurship and startup company development. Twelve students were selected by a committee of American and Russian specialists in economic policy and entrepreneurship to participate in the Yegor Gaidar Summer Leadership Program, which will run from Monday (July 14) through Aug. 2.Read Full Story