Purdue researchers apply new technique to manipulate virus, make it a possible cancer treatment
November 27, 2013
WEST LAFAYETTE, Ind. — Purdue University researchers successfully eliminated the native infection preferences of a Sindbis virus engineered to target and kill cancer cells, a milestone in the manipulation of this promising viral vector.
"This virus had been known to be a good vector for delivering therapeutic cargo, however it naturally infected all kinds of cells, and these diversions would compete with what we were instructing it to target," said Richard Kuhn, the Gerald and Edna Mann Director of Purdue's Bindley Biosciences Center. "We have now overcome a major challenge by not only inserting a targeting molecule of our choice, but also successfully stripping the virus of its native entry preferences. This was a big step in unlocking the potential of developing this virus into a platform for both targeted drug delivery, where it would sneak drugs inside cancer cells, and oncolytic virotherapy, where the virus itself destroys cancer cells."
- Elizabeth K. Gardner, Writer
April 22, 2015
A Purdue University research center is planning its second annual Record the Earth activity for Earth Day on Wednesday (April 22) to capture natural sound recordings and upload them for preservation.Read Full Story
April 10, 2015
Atlas Energy Systems LLC, a Purdue University startup, is one of five finalists in the student track of the 2015 Clean Energy Challenge, a nationally recognized accelerator program for clean energy innovation, run by Chicago-based nonprofit Clean Energy Trust and sponsored by the U.S. Department of Energy.Read Full Story
March 26, 2015
Discovery Park Student Poster Session and Reception. Highlighting undergraduates in DP-affiliated interdisciplinary internships. Organizer: Discovery Learning Research Center. 4:30-6 p.m. Hall for Discovery and Learning Research, Atrium (first floor). Remarks at 5:30 p.m. by Stephen Beaudoin, interim associate vice provost for academic affairs and professor of chemical engineering. Free but RSVP required by April 2; URL: www.purdue.edu/discoverypark/learningcenter/studentevent.phpRead Full Story