- Highly efficient microfluidic platforms using Electrowetting-on-dielectic (EWOD)for cell and tissue cryopreservation
- Development of microchip to quality of bio-transport properties of the engineered tissues
- Interstitial flow measurement of ECM structures using microfludics
Impact Statement & Explanation of Research:
The objective of research is to develop fast and highly efficient microfluidic platforms for: 1) precessing engineered tissues and harvested tissue samples, and 2) characterization and screening of cryoprotective agent mixtures for cell/tissue-type specific cryopreservation. These platforms are a microchannel-based tissue chamber and an "electro-wetting-on-dielectric" (EWOD) -based digital multiplexer. These platforms are also being used to study cell-matrix interaction and interstitial fluid flow.