Electrical and Computer Engineering/Purdue University/2009
Primary collaborative faculty member/s:
Research interestes are in Bionanotechnologies including: BioMEMS, Biosensors, Biomolecular detection, Nano-biomechanical sensors.
Impact Statement & Explanation of Research:
(A) Cellular Detection: Using modern microfabrication technique and optical transmission measurement method to develop a biosensor for whole-cell detection. Targets detected using this system include E. Coli and Bacillus Anthracis spores.
(B) Biomolecular Detection: Combine immunomagneto separation technique and optical diffraction principle to construct a biomolecular sensor. Targets detected include Folate Receptor (FR), a cancer marker circulating in blood, and S-Adenosyl Homocysteine (SAH), a potential diagnostic marker for cardiovascular disease.
(C) Nano-biomechanical detection: Incorporating bacteriophage phi29, one of the most powerful biomolecular motors, with modern AFM and optical measurement technique to achieve biomechanical/biomolecular detection.
Hybrid Bionanomechanical Systems for Sensitive Biomolecular Detection