Affiliated Scientific Core Facilities
Listing of All Purdue Wide Core Facilities
http://www.purdue.edu/research/centers-institutes-cores/cores.php
Select Core Facilities by Drug Discovery Stage
Drug Discovery/Development Related Core Facilities
3T MRI jointly serving research and clinical (InnerVision West)
purposes; accessible for research after 5 PM Monday-Friday and 24 hours Saturday-Sunday; support services offered for MRI, fMRI and MRS
Location: 3482 McClure Ave
Contact: Charles Bouman, Thomas Talavage
Analytical Mass Spectrometry Facility
Consists of two laboratories with eight mass spectrometers and three staff members. Services include a complete range of ionization and sample introduction methods.
https://www.purdue.edu/research/life-sciences/amsf/
Location: BRWN, WTHR, and DRUG
Contact: Ryan Hilger
Amy Analytical Instrumentation Center
The Amy Analytical Instrumentation Center is a core facility in the Department of Chemistry that manages the shared departmental instrumentation.
https://www.chem.purdue.edu/aaic/
Location: WTHR and BRWN
Contact: Mike Everly, Pat Bishop
Arthur Fungarium and Kriebel Herbarium
An Herbarium is a collection of carefully preserved plant and/or fungal specimens; a Fungarium is a collection of carefully preserved fungal specimens. The Department of Botany and Plant Pathology at Purdue University houses two herbaria of immense historical and scientific value. The Arthur Fungarium (herbarium acronym PUR) is the largest specialized Fungarium, containing the most important collection of plant rust fungi (order Pucciniales), in the world. The Kriebel Herbarium (acronym PUL) contains non-rust fungi, vascular plants, lichens, algae and bryophytes, and is the oldest herbarium in the state of Indiana. Together the collections contain close to 250,000 specimens dating as far back as 1769 and gathered from across the globe. The collections are an important global resource for scientists and researchers in the fields of botany, mycology, plant pathology, forestry and biology. PUR and PUL arrange for loans of material to other herbaria and researchers around the world, accept material for deposition to voucher scientific studies, and serve as a resource for identifying rust fungi and their host plants from around the world.
https://ag.purdue.edu/btny/Herbaria/Pages/default.aspx
Location: LILY G-447
Contact: M. Catherine Aime
Bioinformatics Core
Facilitate, amplify, and accelerate biological research and discovery through application of bioinformatics. Deliver high quality analysis and consultation in a timely and economical manner. Support workshops and learning activities. Support computational resources.
https://www.bioinformatics.purdue.edu/
Location: Young Hall
Contact: Jyothi Thimmapuram
Bioinformatics and Discovery Systems Lab
The lab is used to carry out common genomic biotechnology methods in collaboration w/ other groups on campus, as well as develop new methods for detecting DNA biomarkers and developing innovative information management systems in support of genomics research. The lab is equipped with a DNA microarray spotter, and DNA microarray scanner, most often used for gene expression studies.
http://bioinformatics.tech.purdue.edu/
Location: Knoy B020
Contact: Michael Kane
Biomolecular Cleanroom
2,500 Sq. ft. Bio-Nanotechnology Integration Laboratory
http://www.purdue.edu/discoverypark/nanotechnology/facilities/
Location: Birck Nano
Contact: Guy Telesnicki
Biophysical Analysis Laboratory
Analysis of proteins, DNA, RNA, and other molecules
http://www.purdue.edu/discoverypark/bioscience/facilities/core/biophysical/index.php
Location: Bind 234B
Contact: Jia Ma
Bioscience Imaging Facility
We provide the instruments and expertise needed to visualize molecules in preparations ranging from single cells to entire animals. All facility users receive individualized instrument training as well as project specific advice for optimal data acquisition. Consultation on sample preparation, image rendering, and data analysis are also available as our knowledge base permits.
http://www.purdue.edu/discoverypark/bioscience/facilities/core/bioscience/index.php
Location: HANS B032
Contact: Andy Schaber
Birck Nanotechnology Center BioNanotechnology Laboratories (BNC-BNL)
BNC-BNL is located at the Birck Nanotechnology center. It provides researchers a place where they can take their drug delivery (e.g. BioMEMS/NEMS or Biosensor) device or nanoparticle-driven from idea stage to a viable prototype to invitro testing and basic sterility testing. A CTSI core facility.
https://engineering.purdue.edu/VPR/CORES/ptUnit?unit=Discovery%20Park
Location: Birck Nano
Contact: James Leary
Bone & Body Composition Core
The Bone and Body Composition Core provides services and methods for determining bone density, bone geometry, and body composition in humans and animals. The following equipment and services are available to Purdue researchers along with Indiana CTSI members: (1) A GE/Lunar iDXA (Dual Energy X-ray Absorptiometry) (for humans). Provides scans of the whole body, lumbar spine, femur neck, and forearm. (2) A Stratek XCT 2000, peripheral quantitative computed tomography (pQCT) (for Humans). Used primarily for forearms and lower legs. Also has been used to measure excised porcine femurs. (3) A GE/Lunar Prodigy DXA (for animals). Provides whole body scans for small and medium sized animals, and specific bone scans for larger animals. (4) The Scanco MicroCT u40. Provides 3D imaging as well as quantitative measurements. Samples must be smaller than 35 mm in diameter and 75 mm in length. (5) Histology Services are located at IUPUI, Indianapolis. Dr. Burr and staff from the Department of Anatomy and Cell Biology at the Indiana University School of Medicine provide histological services for basic science (non-clinical) research. Both mineralized (plastic embedded) and soft tissue (paraffin embedded) specimens can be prepared.
Location: Stone Hall, Room 149
Contact: Connie Weaver, Pam Lachcik
Campus-wide Mass Spectrometry Center
The Campus-wide Mass Spectrometry Center (CWMSC) is a campus-wide facility. All major mass spectrometric ionization techniques and sample introduction methods are available, including gas chromatography, liquid chromatography, electron impact, chemical ionization, electrospray ionization, inductively coupled argon plasma, matrix-assisted laser desorption ionization, atmospheric pressure chemical ionization and high resolution mass measurements.
http://www.chem.purdue.edu/cwmsc
Location: WTHR, DRUG, RHPH
Contact: Karl Wood
Center for Analytical Instrumentation Development
Develop the next generation of analytical instrumentation for chemistry, life science and point-of-need applications in medicine, industry, and public safety. Expand participation to other regional institutions. Prominent among these instrumental methods is the application of mass spectrometry to problems of national and world interest and the miniaturization of mass spectrometry to further those aims.
http://www.purdue.edu/dp/caid/
Location: Bind B019
Contact: Brandy Schumaker
Center for Materials Processing and Tribology - Metrology Laboratory
Surface and mechanical property characterization
https://engineering.purdue.edu/~tribmat/
Location: MGL 1317
Contact: James B. Mann, S. (Chandy) Chandrasekar, W. Dale Compton
Chemistry Glass Shop
The Glass Shop is currently part time and services the entire campus for scientific glass blowing service.
http://www.chem.purdue.edu/glasslab/
Location: WTHR
Contact: Mike Everly
Chemistry Machine Shop
The Machine Shop provides custom tooling and design/fabrication for building technical equipment.
http://www.chem.purdue.edu/machine/
Location: WTHR
Contact: Mike Everly
Clinical Research Center (CRC)
The Indiana CTSI Clinical Research Center (CRC) provides space, nursing, and sample processing support to conduct academic and industry sponsored clinical research studies for both inpatient and outpatient visits. The program maintains facilities at both Indiana and Purdue Universities, and is available for use by researchers from both institutions. Medically trained staff provides services and support in phlebotomy, intravenous catheter placement, serial blood draws, infusions/injections, protocol development, and reference lab tests. The bionutrition staff supports CRC investigators’ research by providing dietary expertise and nutrition research services including: budget consultation, research diets, meal preparation and service, nutritional counseling, dietary recalls and diaries, nutritional analysis, dietary homogenates, oversight of subject randomization, coding and/or blinding for dietary protocols, facilities to support clinical research.
https://www.indianactsi.org/clinical-research-support/crc/
Location: Stone Hall, Lyles-Porter Hall
Contact: Scott Denne, Connie Weaver
Computational Life Sciences and Informatics
Development and application of computational tools and techniques to solve complex life science problems, specializing in mass-spectrometry differential omics, including custom data management, database analysis and design, and software development.
http://www.purdue.edu/discoverypark/bioscience/facilities/core/computational/index.php
Contact: Tiago Sobreira
Cryo-EM Facility
The Cryo-EM Facility operates several high field transmission electron microscopes equipped for cryo-microscopy of biological assemblies.
Location: HOCK
Contact: Valorie Bowman, Wen Jiang
Electron Microscopy
Electron Microscopy facility in Birck has Hitachi S4800 cold field-emission scanning electron microscope, equipped with STEM capability; FEI Nova 200 Dual Beam system, equipped with a Kl?cke nanomanipulator for site specific sample preparation; and FEI Environmental S/TEM 80-300 Titan.
http://www.purdue.edu/discoverypark/nanotechnology/facilities/
Location: Birck Nano
Contact: Rosa Diaz
Envision Center
The mission of Envision Center for Data Perceptualization is to serve, support, and collaborate with faculty, students, and industry to be a leader in scientific visualization, immersive environments and human computer interaction, through learning, discovery, and engagement.
https://www.rcac.purdue.edu/envision/
Location: STEW B001
Contact: RCAC Info
Epitaxy
The Epitaxy recharge center consists of three deposition tools for thin film research as well as a high resolution x-ray diffractometer for thin film characterization. Equipment in recharge center: Nitride Sputter System (PVD Products), Oxide Pulsed Laser Deposition (PVD Products), High resolution x-ray diffractometer HRXRD (PANalytical), Organometallic vapor phase epitaxy/Metalorganic chemical vapor deposition OMVPE/MOCVD (Aixtron), Laser annealing (Lambda Physik), Laser lift-off (Lambda Physik).
http://www.purdue.edu/discoverypark/nanotechnology/facilities/
Location: Birck Nano
Contact: Ron Reger
Flow cytometry and cell separation facility
The Bindley Bioscience Flow Cytometry and Cell Separation Facility provides advanced cell and particle analysis and sorting using flow cytometry based technology. The facility also provides training in flow cytometry analysis and sorting techniques. The facility also provides expert consultation for assay and protocol development for flow cytometry analysis and cell separation.
http://www.purdue.edu/discoverypark/bioscience/facilities/core/flow/index.php
Location: Bind 233
Contact: Jill Hutchcroft
Food Science Pilot Laboratory
Wet chemistry, microbiology, and food product development
http://www.ag.purdue.edu/foodsci/Pages/pilot_plant.aspx
Location: Food Science
Contact: Steve Smith
Gamma Irradiator
Provide gamma irradiation/sterilization for cells, media, etc.
Location: North Campus
Contact: James Schweitzer
Genomics Core Facility
The Purdue Genomics Core facility has more than a decade of experience in DNA sequencing and provides "next generation", high and low-throughput sequencing services as well as first-pass informatics support.
http://www.genomics.purdue.edu/
Location: WLSR S045
Contact: Phillip SanMiguel
HUBzero
HUBzero is a powerful, open source software platform for creating dynamic web sites that support scientific research and educational activities.
Location: Young
Contact: Michael Zentner
High-Performance Computing and Cyberinfrastructure Research Lab
a focal point for education, research, and collaboration in the development, deployment, and use of supercomputing, grid computing, and cyberinfrastructure. The HPC-CRL is the first College of Technology Exploration Center, which is designed to support and enhance teaching, research, and collaboration among faculty, students, and industrial partners. The lab consists of three areas: research, collaboration, and education.
Location: Knoy 208
Contact: Thomas Hacker
High Performance Computer Graphics Laboratory
The research in the HPCG-Lab is divided into diverse projects, all having in common the use of High Performance Computer Graphics algorithms and tools as the means of providing high performance computation, real-time rendering, and scientific visualization research.
Location: Knoy
Contact: Bedrich Benes
Histology and Pathology
The Histology Research Laboratory is a full service histology laboratory that provides tissue embedding, slide preparation, staining and immunohistochemistry service. Consultation and collaborations with board-certified pathologists are also available.
https://vet.purdue.edu/ctr/histology/services.php
Location: VPRB, B15
Contact: Histology@purdue.edu
ICP-MS for Elemental Analysis of Liquids
ICP-MS for Elemental Analysis of liquids or liquid extracts/digests of solid samples
https://engineering.purdue.edu/VPR/CORES/ptUnit?unit=Agriculture
Location: Lily
Contact: Linda Lee
Interdepartmental NMR Facility
The Purdue Interdepartmental NMR Facility (PINMRF) is a university-wide resource dedicated to supporting NMR spectroscopy and to making this analytical technique available to researchers at Purdue and elsewhere in the scientific community. PINMRF currently has ten NMR spectrometers located in four buildings on the Purdue campus, with additional laboratory locations under consideration. PINMRF is set up to allow individual researchers direct access 24/7 to the spectrometers, after appropriate training and testing has been completed. However, we will gladly provide spectra of submitted samples, either on a service basis or as part of a collaborative research project.
Location: WTHR, BRWN, RHPH, DRUG
Contact: Dr. John Harwood
Life Sciences Electron Microscopy Facility
The LSMF is a full service electron microscopy core with both service and individual use options. Equipment includes two field-emission SEMs (Nova NanoSEM and Quanta3D FEG) equipped with cryo, EDX, low vacuum and ESEM capability, and tensile stage. The Quanta 3D FEG is a dual beam instrument with an ion beam for milling, slicing and deposition. Also available are 2 TEMs (CM100 and a Tecnai G2 T20) each with great CCD cameras. The 200KV Tecnai has STEM with an HAADF detector. This instrument is also set up with software for automated electron tomography acquisition for 3D reconstruction. In addition the Tecnai is equipped with a SDD x-ray detector for elemental analysis and mapping. The lab has ultramicrotomes (room temperature and cryo), a microwave processing system and a vibratome. For cryo preparation there is a high pressure freezing device and automated freeze substitution. The staff are knowledgeable and friendly and happy to discuss projects and work with you on your science questions.
https://ag.purdue.edu/arp/Microscopy/Pages/default.aspx
Location: WLSR
Contact: Christopher Gilpin
Lilly Animal Care Facility
Users are BME, SLHS, Vet School, Endocyte, along with Biological Sciences.
Location: LILY-LSA
Contact: Cindy Sanow
LSM 710 Confocal Microscope
Inverted Zeiss LSM 710 confocal laser scanning microscope with and environmental chamber appropriate for live cell imaging. Advanced methods available include spectral unmixing, time lapse, multi-target imaging, FRET, FRAP, photoactivation, and ratiometric imaging of ion indicator dyes.
https://www.bio.purdue.edu/confocal/
Location: Lilly
Contact: Don Ready
Macromolecular Crystallography
Macromolecular crystallography laboratory; crystallization and X-ray Diffraction. A core facility of the Purdue Center for Cancer Research.
https://www.cancerresearch.purdue.edu/research/resources/macromolecular-crystallography
Location: HOCK 320
Contact: Calvin Steussy, Tim Schmidt
Metabolite Profiling Facility (MPF)
The laboratory utilizes gas chromatography and liquid chromatography coupled with mass spectrometry for the analyses of small, biological molecules. We collaborate with research investigators who are conducting metabolomic studies, by providing technical assistance with sample preparation, data acquisition, analysis, and interpretation of experimental information. The lab performs both quantitative analysis and non-targeted molecular screening.
http://www.purdue.edu/discoverypark/bioscience/facilities/core/metabolite/index.php
Location: Bind 134
Contact: Amber Hopf Jannasch
Microwave Plasma Chemical Vapor Deposition -- MPCVD
This Microwave Plasma Chemical Vapor Deposition system (SEKI-5200S) produces a variety of carbon-based nano- and micro-materials including carbon nanotubes, graphene, and diamond thin films. It operates at moderate pressure near 10 Torr with typical process gas mixtures consisting of hydrogen and methane. The system features an inductively heated stage, 1-2 inch active deposition area, temperature control through thermocouples supplemented by a dual-wavelength pyrometer, and recently added laser diagnostics of plasma species.
http://www.purdue.edu/discoverypark/nanotechnology/facilities/
Location: Birck Nano
Contact: Tim Fisher
MSE Microscopy Facility
The MSE Microscopy Facility contains 2 Transmission Electron Microscopes and 3 Scanning Electron Microscopes for use in research and analysis. The SEMs have Energy Dispersive X-ray Spectroscopy (EDS) capability, and one SEM also has Electron Backscatter Diffraction Analysis (EBSD). The facility contains a sample preparation laboratory with basic tools and supplies for EM sample preparation. In addition there are 2 Atomic Force Microscopes, one small sample stage and one large sample stage that has a wide variety of attachments for a variety of experiments. The large stage AFM also has Piezoresponse Force Microscopy (PFM) and Scanning Thermal Microscopy (SThM) capability.
https://engineering.purdue.edu/MSE/Research/Facilities/Microstructural/EM-Facility.html
Location: ARMS
Contact: John Blendell
MSE X-Ray Characterization Facility
Specialized X-Ray Analysis
https://engineering.purdue.edu/MSE/Research/Facilities/XRayFacility/index.html
Location: ARMS
Contact: Keith J. Bowman, Patti Metcalf
Optics and Spectroscopy
Spectrophotometer Lambda 950; Micro-Sample Spectrometer; Raman Spectrometer T64000 with the excitation lasers: tunable Ar/Kr, CW 10 mW per wavlength, 10 wavelength accross the visible rangefemtosecond/picosecond regenerative amplifier-OPA system; Nanonics NSOM/ Luminescence Mapping with the excitations lasers: HeNe 633 nm, solid state 532 nm, Diode 785 nm.
http://www.purdue.edu/discoverypark/nanotechnology/facilities/
Location: Birck Nano -- Lab BRK1273
Contact: Alexei Lagoutchev
Physiological Sensing Facility
Cellular and tissue metabolism, cell-signaling, neurophysiology, environmental toxicology, biosensing, bionanomaterials, lab-on-a-chip systems, bioMEMS, biophysical sensing
http://www.purdue.edu/discoverypark/psf/
Location: Bind B025 / BRK 2120
Contact: Jenna Rickus, Marshall Porterfield
Polytechnic Precision Measurement Center
The Purdue Polytechnic Precision Measurement Center at the statewide location in Columbus, Indiana, is an environmentally-controlled (20 degrees C plus/minus 0.5 degrees C, Positive Pressure; Humidity < 35%) laboratory that is certified annually. Examples of calibrated equipment include a Zeiss Coordinate Measuring Machine, an Instron tensile test machine, a Zeiss surface finish tester, a Fluke dead-weight tester for calibrating pressure gauges, and sets of English and metric gauge blocks. Additionally, there are tools for measuring torque, force, hardness, and mass as well as numerous hand and optical tools for dimensional measurement.
https://polytechnic.purdue.edu/columbus/measurement-center
Location: Room 137; Advanced Manufacturing Center of Excellence; Columbus, Indiana
Contact: Joe Fuehne
Proteomics Facility
Mass spectrometry analyses of peptides and proteins. Maldi and ESI analysis, comparative proteomics, peptides sequencing, proteins identification and analysis, database search analysis , quantitative analysis, biomarkers discovery, proteins digestion. Amino acid analysis
http://www.purdue.edu/discoverypark/bioscience/facilities/core/proteomics/
Location: BIND 134
Contact: Uma Aryal
Research Machining Services
Precision machine shop, open to all departments, with both standard and CNC machining equipment, welding, and design services. Work with wide variety of materials, including steels, aluminums, stainless steels, and brass plus special-order metals and high-performance plastics. Able to satisfy needs for plating, anodizing, and water jetting services, along with many other services through vendors. Specialize in one-of-a-kind research equipment and/or modifications.
http://www.purdue.edu/DP/machineshop/
Location: ADM Agricultural Innovation Center
Contact: Kris Davis
PRIME Lab
The Purdue Rare Isotope Measurement Laboratory (PRIME Lab) is a dedicated research and service facility for accelerator mass spectrometry (AMS). AMS is an ultra-sensitive analytical technique for measuring low levels of long-lived radionuclides and rare trace elements. The accelerator is used to measure both man-made and cosmic-ray-produced radionuclides such as 10Be (half-life 1,600,000 years), 14C (5730 years), and 36Cl (300,000 years) in natural samples having isotopic abundances down to one part in 1x1015 (a thousand million million).
http://www.physics.purdue.edu/primelab/
Location: PHYS
Contact: Marc Caffee
Research Repository (PURR)
PURR utilizes HUBzero™, a software platform designed for scientific collaboration and sharing of research data on the web. Any Purdue graduate student, faculty, or staff can create a project in PURR and receive a default allocation of storage. PURR provides capabilities currently required by the NSF for digital data management such as workflows and tools for collaborating on data-driven research, publishing and archiving data, and ensuring data security, fidelity, backup, and mirroring. Purdue librarians consult with investigators to facilitate selection and ingestion of data with appropriate descriptive metadata and data standards and provide long-term digital preservation and stewardship. PURR comes with a set of default policies and functionality that addresses privacy and confidentiality, intellectual property, and access and use of research data. Datasets published using PURR are assigned Digital Objects Identifiers (DOIs) and exposed to the web using open standards to maximize their discoverability and scholarly reuse.
Location: Libaries, HUBzero
Contact: Michael Witt
SAXS/USAXS Facility
Small Angle X-ray Scattering and Ultrasmall Angle X-ray Scattering for characterization of nanoparticles, nanomaterials and nanostructures
https://engineering.purdue.edu/VPR/CORES/ptUnit?unit=Engineering/
Location: FRNY
Contact: M.T. Harris
Scientific Solutions
The Scientific Solutions group works with Purdue faculty and staff to develop proposals and specific research solutions, including computation, data-intensive applications, geospatial data processing and software, science portals, web programming and other programming services. https://www.rcac.purdue.edu/services/software/; https://www.rcac.purdue.edu/services/partner/
https://www.rcac.purdue.edu/services/software/
Location: Young
Contact: Carol Song
Scifres Nanofabrication Cleanroom
25,000 sq. ft. Class 1-10-100 Nanofabrication Laboratory
http://www.purdue.edu/discoverypark/nanotechnology/facilities/
Location: Birck Nano
Contact: Ron Reger
Soft Materials Characterization Laboratory
This lab is dedicated to the characterization and analysis of polymeric and other soft materials. It currently contains TA Instruments Q2000 Dynamic Scanning Calorimeter (DSC) capable of -180C to 700C operation, a TA Instruments Q800 Dynamic Mechanical Analyzer (DMA) with humidity controller, and a Rame-Hart Digital Automated Dynamic Contact Angle Goniometer.
https://engineering.purdue.edu/MSE/research/facilities/CharacterizationFacilities/SoftMaterials/
Location: ARMS B214
Contact: Jeffrey Youngblood
SPM
Scanning Probe Microscopy, Nanotec Air STM, Omicron UHV STM
http://www.purdue.edu/discoverypark/nanotechnology/facilities/
Location: Birck Nano
Contact: Ron Reifenberger
Stable Isotope Facility
PSI houses three gas Isotope Ratio Mass Spectrometers (IRMS), each accompanied by peripheral devices for conversion of various compounds into analyzable gases.
http://www.eas.purdue.edu/psi/
Location: CIVL
Contact: David Gamblin
Surface Analysis
Kratos XPS; Omicron Surface Analysis Cluster
Location: Birck Nano
Contact: Dmitry Zemlyanov
Transgenic Mouse Core Facility
The Transgenic Mouse Core Facility (TMCF) offers a variety of services to the Purdue University Center for Cancer Research community, including (1) Generation of Transgenic Mice, (2) Gene Targeting of ES Cells, (3) Blastocyst Injection of ES Cells for the Generation of Knock-Out Mice, (4) Strain Rederivation, (5) In Vitro Fertilization, (6) Embryo Cryopreservation, (7) Chromosome Counting, (8) Mouse Embryonic Fibroblast (MEF) Cell Line Production, (9) Speed Expansion, (10) Sperm Cryopreservation, (11) Genotyping, (12) Mouse Production Colony, (13) Mouse Dedicated Supply – Colony Set Up, (14) Rat Transgenic/KO Production.
http://www.cancerresearch.purdue.edu/research/resources/transgenic-mouse
Location: Bindley Bioscience Center
Contact: Judy Hallett
Translational Pharmacology Facility
In vivo pharmacology with swine and mouse/rat model and unique PigTurn monitoring and sampling system
http://www.purdue.edu/discoverypark/bioscience/facilities/core/pharmacology/capabilities.php
Location: Vet animal holding
Contact: Robyn McCain
Vistec Ebeam
Vistec VB6 Electron Beam Lithography Writing Tool
Location: Birck Nano
Contact: Minghao Qi
X-ray Crystallography
Data collection, structure analysis, and crystallography consulatation services.
https://www.chem.purdue.edu/xray/
Location: WTHR 101
Contact: Dr. Matthias Zeller