Phillip A. Sharp is Institute Professor at the David H.
Koch Institute for Integrative Cancer Research
(formerly the Center for Cancer Research) at the
Massachusetts Institute of Technology. He received
the Nobel Prize in Physiology or Medicine in 1993
for his landmark work on the molecular biology of
gene expression relevant to cancer and the
mechanisms of RNA splicing.
His lab has now
turned its attention to understanding how RNA
molecules act as switches to turn genes on and off
(RNA interference). These newly discovered
processes have revolutionized cell biology and could
potentially generate a new class of therapeutics.
Sharp’s work has earned him numerous cancer
research awards and presidential and national
scientific board appointments. He is elected
member of the National Academy of Sciences and
the Institute of Medicine. He is also the recipient of
the National Medal of Science.
Dr. Sharp earned a
B.A. degree from Union College, KY, and a PhD in
chemistry from the University of Illinois. He is the
cofounder of Biogen (now Biogen Idec) and Alnylam
Pharmaceuticals and serves on the boards of both
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