Bioinformatics Seminar - October 3, 2012
October 3 @ 1:30 PM - 2:30 PM - Lilly 1-117
"Integrating Structural Biology, Bioinformatics and Cheminformatics to Understand Molecular Recognition" by Dr. Joe Schoeniger, Distinguished Member of the Systems Biology Department at Sandia National Labs, Livermore, CA.
October 3 (Wednesday)
Place: Lilly 1-117
At Sandia/California, I have established programs to develop biosensors and bioanalytical instrumentation. I also cofounded a major facility, the Chemical and Radiation Detector Laboratory. My recent research activities, funded by the Department of Energy and other government sponsors, have focused on (1) the development of novel microseparations methods for proteins, peptides, and DNA; (2) the intersection of these methods with classical protein chemistry; and (3) analytical methods, such as high-resolution mass spectrometry, for solving outstanding problems in proteomics and structural genomics.
I have also initiated the following projects during my Sandia career:
- The development of an organophospate sensor based on enzyme-coated ion-sensitive field-effect transistors.
- The use of sol-gel techniques for improved fiberoptic sensors.
- The development of ultrasensitive fluorescence-based assays for biotoxins using self-assembled materials.
- Affinity electrochromatography with laser-induced fluorescence detection.
- Microelectrode array-based sensors for pathogen detection.
- The use of combinatorial chemical synthesis and computational design of molecular-recognition materials for sensor and antitoxin development