Diet & Disease Prevention
The organizational and intellectual infrastructure of the Bindley Bioscience Center provides a versatile platform for the systematic investigation of numerous dietary, disease and health related issues, including osteoporosis, cancer, cardiovascular disease, diabetes, obesity and inflammation. It also provides a stimulating environment for a dynamic and broad range of faculty to translate novel ideas into focus-driven discoveries in the diet, disease and health arena. With further development, this capacity will be scalable, allowing for rapid growth into priority areas as opportunities arise.
Molecular Biomarker Research
The complexity of both the chemical composition of foods and the body's molecular and physiological response to diet creates discovery challenges. The dynamic response and interaction of an organism's genome with its transcriptome, proteome, metabolome and ionome defines how a living system functions and progresses towards health or disease. Unraveling these interconnections and applying them to the prevention of disease and promotion of health is one of the great challenges in modern medical science.
Identification of disease and diet associated composite molecular biomarkers will facilitate identification of new molecular targets for development of novel therapeutic agents to address diet-related chronic diseases. In combination with emerging bio-chip technologies, such composite biomarkers for diet and health will also revolutionize the "wellness" economic sector. Biomarker technologies for identification of early signs of chronic disease, along with foods for its prevention, will allow prevention to become a commercially viable sector of the health industries.
Such readily available biomarkers for health and healthful foods will also drive the new and emerging sector of personalized health care. These drivers will promote the development of value-added agricultural crops and foods around the concept of prevention rather than cure. Such activities will engage and benefit the agricultural, food, pharmaceutical and health related economic sectors regionally, nationally and internationally.
The interdisciplinary research focus of Diet & Disease Prevention is designed to address the clearly articulated problem of reducing the epidemic of diet-related chronic disease in the United States through the application of Systems Biology. The system necessary to implement this focused effort requires a transdisciplinary team drawn from across the Purdue academic units and within Discovery Park, including researchers from Plant and Animal Sciences, Agriculture, Food Science and Nutrition, Comparative Medicine, Clinical Sciences, Pharmacy, Instrumentation Sciences, Computation and Information Processes, Library Sciences, Communications and Engineering. Such broad expertise is coalesced around four core programmatic areas:
Each functionality is laterally integrated and, as a working whole, will deliver Systems Biology knowledge on the interconnections of diet, disease and health.
The first three programmatic themes are closely affiliated, and a high level of lateral integration is required to deliver quality Systems Biology data. Such integration is achieved by the involvement of multiple faculty with interlocking interests, from disciplines spanning all three themes, including Department of Food Science, Department of Horticulture, Department of Foods and Nutrition, Department of Animal Sciences, Department of Veterinary Clinical Sciences.
Knowledge from these four programmmatic areas is iteratively fed back into the discovery and learning process. Furthermore, this environment acts as an engagement portal for the dissemination of knowledge to a broader community of students, educators, researchers and entrepreneurs.
Diet & Disease Executive Management Committee
The Diet & Disease Executive Management Committee provides the strategic vision, leadership and coordination of the development of the integrated biological, analytical and cyber infrastructure. Members include:
David E. SaltProfessor, Department of Horticulture and Landscape Architecture
Scientific Director for Genomics, Bindley Bioscience Center.
James FleetDistinguished Professor, Department of Nutrition Science.
Michael GribskovProfessor, Department of Biological Sciences.
Joe PeknyProfessor, Department of Chemical Engineering
Director of e-Enterprise Center
James MullinsDean and Professor of Libraries.
A diverse team of faculty with overlapping interests is involved with the Diet & Disease research area.
Department of Computer Graphics Technology
Department of Communications
Department of Biological Sciences
Research That Affects Us All
Interdisciplinary life sciences and engineering researchers collaborate to explore new technologies and scientific knowledge that impact the broad boundaries of plant, animal, and human diseases.
- Center for Analytical Instrumentation Development (CAID)
- Center for Global Research and Intervention in Infectious Diseases (C-GRIID)
- Clinical Proteomic Technologies for Cancer (CPTC)
- Indiana Clinical and Translational Science Institute (Indiana CTSI)
- Center for Direct Catalytic Conversion of Biomass to Biofuels (C3Bio)
No current events were found.
Bindley Bioscience Center
1203 W. State Street
West Lafayette, IN 47907-2057
- Phone: 765.496.6147