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| Email: |
| fleet@purdue.edu |
| Office: |
| G-1D
Stone Hall |
| Phone: |
| ( 765)
494-0303 |
| Fax: |
| (765)
494-2180 |
|
James
C. Fleet
Ph.D.
Cornell University, 1988
Associate
Professor of Foods and Nutrition |
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| Research
Interests: |
| Vitamin D, impact on calcium metabolism, prostate cancer,
Regulation of mineral metabolism, Intestinal biology,
Impact of aging on biological function |
| |
| Teaching
Interests: |
Presentation
skills for Graduate students (FN695)
Nutritional Biochemistry and Physiology I (FN590B)
Nutrition and Genetics (FN special topics course) |
| |
| Grants
Received From: |
- National
Institutes of Health
-
US Veterans Administration
-
US Department of Agriculture
-
Private industry and foundations
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| Recent
Publications: * |
- Higher 1,25 dihydroxycholecalciferol-mediated gene expression and calcium absorption in female mice.
- HNF1-alpha and cdx-2 control calbindin D9k gene expression during cellular differentiation.
- Short-term low protein intake does not increase serum parathyroid hormone concentration in humans.
- Vitamin D-inducible calcium transport and gene expression in three Caco-2 cell lines.
- Excentric cleavage products of beta carotene inhibit estrogen receptor (ER) positive and ER negative breast tumor cell growth in vitro.
- Vitamin
D receptor (VDR) knockout mice reveal VDR-independent
regulation of intestinal calcium absorption, ECaC2,
and calbindin D9k.
- Vitamin
D receptor alleles, periodontal disease progression
and tooth loss in the VA dental longitudinal study.
- Gene
Expression Profiling of Caco-2 BBe Cells Suggests
a Role for Specific Signaling Pathways during Intestinal
Differentiation .
- CaT1
and ECaC mRNA are differentially regulated by 1,25
dihydroxyvitamin D3 in intestine and kidney of mice.
- Effect
of cellular environment on the selective activation
of the vitamin D receptor by 1,25-dihydroxyvitamin
D3 and its analog Ro-26-9228.
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*
To see a more detailed description of publications
click the book: 
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| Links
of Interest: |
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Ernest C. Young Hall Room 828| 302 Wood Street | West Lafayette, IN 47907-2108
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