Kevin M. Sowinski
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Contact Information Email: ksowinsk |at| iupui.edu Office: RHPH 302 Map Phone: (317) 613-2315 (ext. 310) Fax: (317) 613-2316 Homepage: Homepage |
Professor of Pharmacy Practice |
Education
B.S. State University of New York at Buffalo Pharmacy 1990
Pharm. D. University at Buffalo,State University of New York 1992
Research Interests
Sex-related differences in drug pharmacokinetics and response; Impact of renal disease and dialysis on drug pharmacokinetics and response; Mathermatical modeling of pharmacokinetic and pharmacodynamics; Cardiovascular pharmacokinetics and pharmacodynamics, Effect of aging on drug disposition and responsiveness
Teaching Interests
Cardiovascular Pharmacotherapeutics, Clinical Research Methods, Clinical Pharmacokinetics
Grants
American College of Clinical Pharmacy Research Institute
National Kidney Foundation of Indiana
American Foundation for Pharmaceutical Education
Purdue University Gerontology Program
American Heart Association
Tennessee Affiliate
Publications
Liang H, Kays MB, Sowinski KM. Separation of levofloxacin, ciprofloxacin, gatifloxacin, moxifloxacin, trovafloxacin and cinoxacin by high-performance liquid chromatography: application to levofloxacin determination in human plasma. J Chromatogr B 2002;772:53-63.
Sowinski KM, Lucksiri A, Kays MB, Scott MK, Mueller BA, Hamburger RA, Levofloxacin pharmacokinetics in end-stage renal disease and removal by the CAHP-210 hemodialyzer. Am J Kidney Dis 2003;42:342-349
Overholser BR, Kays MB, Sowinski KM. Determination of gatifloxacin in human serum and urine by high-performance liquid chromatography with ultraviolet detection. J Chromatogr B 2003,798:167-17
Mueller BA, Pasko DA, Sowinski KM. Higher renal replacement therapy dose delivery influences on drug therapy. Artif Organs 2003;27:808-14.
Kays MB, Overholser BR, Mueller BA, Moe SM, Sowinski KM. Effect of sevelamer and calcium acetate on the relative oral bioavailability of ciprofloxacin. Am J Kidney Dis 2003;42:1253-9.
Murray MD, Young JM, Morrow DG, Weiner M, Tu W, Hoke SC, Clark DO, Stroupe KT, Wu J, Deer MM, Bruner-England TE, Sowinski KM, Smith FE, Oldridge NB, Gradus-Pizlo I, Murray LL, Brater DC, Weinberger M. Methodology of an ongoing, randomized, controlled trial to improve drug use for elderly patients with chronic heart failure. Am J Geriatr Pharmacother 2004;2:44-5
Overholser BR, Kays MB, Forrest A, Sowinski KM. Effect of sex on ciprofloxacin pharmacokinetics. J Clin Pharmacol 2004;44:1012-
Sowinski KM, Kays MB. Determination of ciprofloxacin concentrations in human serum and urine by HPLC with ultraviolet and fluorescence detection.. J Clin Pharm Ther 2004;29:381-7.
Sowinski KM, Kronin DA, Mueller BA, Kraus MA. Subcutaneous terbutaline use in chronic kidney disease to reduce potassium concentrations. Am J Kid Disease 2005, in press.
Overholser BR, Kays MB, Lagvankar S, Goldman M, Sowinski KM. Pharmacokinetics of intravenously administered levofloxacin in men and women. Pharmacotherapy 2005, in press.
Kays MB, Overholser BR, Lagvankar S, Goldman M, Sowinski KM. Effect of Ensure on the oral bioavailability of gatifloxacin. Pharmacotherapy 2005, in press.