Faculty Associates

Jason R. Cannon

Contact Information
Email: cannonjr |at| purdue.edu
Office: HAMP 1271 Map
Phone: (765)-494-0794
Fax: (765)-496-1377
Homepage: Homepage
Assistant Professor of Health Sciences and Toxicology

PubMed Listing
Google Scholar Listing

Research Interests


Neurodegeneration, Neurotoxicology, Parkinson's disease, Gene-therapy

Teaching Interests


Toxicology, Analytical Toxicology, Toxicologic Pathology

Publications


Cannon, J. R., Geghman, K. D., Tapias, V., Sew, T., Dail, M. K., Li, C. Greenamyre, J. T. (2013) Expression of human E46K-mutated alpha-synuclein in BAC-transgenic rats replicates early-state Parkinson's disease features and enhances vulnerability to mitochondrial impairment. Exp Neurol. 240, 44-56.

Milanese, C., Sager, J. J., Bai, Q., Farrell, T. C., Cannon, J. R., Greenamyre, J. T. and Burton, E. A. (2012). Hypokinesia and reduced dopamine levels in zebrafish lacking beta- and gamma1-synucleins. The Journal of biological chemistry 287(5), 2971-83, 10.1074/jbc.M111.308312.

Cannon, J. R. and Greenamyre, J. T. (2011). The role of environmental exposures in neurodegeneration and neurodegenerative diseases. Toxicol Sci 124(2), 225-50, 10.1093/toxsci/kfr239.

Cannon, J. R., Sew, T., Montero, L., Burton, E. A. and Greenamyre, J. T. (2011). Pseudotype-dependent lentiviral transduction of astrocytes or neurons in the rat substantia nigra. Exp Neurol 228(1), 41-52, 10.1016/j.expneurol.2010.10.016

Cannon, J. R. and Greenamyre, J. T. (2010). Neurotoxic in vivo models of Parkinson's disease recent advances. Prog Brain Res 184, 17-33, 10.1016/S0079-6123(10)84002-6.

Drolet, R. E., Cannon, J. R., Montero, L. and Greenamyre, J. T. (2009). Chronic rotenone exposure reproduces Parkinson's disease gastrointestinal neuropathology. Neurobiology of disease 36(1), 96-102, 10.1016/j.nbd.2009.06.017.

Cannon, J. R., Tapias, V., Na, H. M., Honick, A. S., Drolet, R. E. and Greenamyre, J. T. (2009). A highly reproducible rotenone model of Parkinson's disease. Neurobiology of disease 34(2), 279-90.

Cannon, J. R., Hua, Y., Richardson, R. J., Xi, G., Keep, R. F. and Schallert, T. (2007). The effect of thrombin on a 6-hydroxydopamine model of Parkinson's disease depends on timing. Behav Brain Res 183(2), 161-8, 10.1016/j.bbr.2007.06.004.

Cannon, J. R., Keep, R. F., Schallert, T., Hua, Y., Richardson, R. J. and Xi, G. (2006). Protease-activated receptor-1 mediates protection elicited by thrombin preconditioning in a rat 6-hydroxydopamine model of Parkinson's disease. Brain Res 1116(1), 177-86.

Cannon, J. R., Keep, R. F., Hua, Y., Richardson, R. J., Schallert, T. and Xi, G. (2005). Thrombin preconditioning provides protection in a 6-hydroxydopamine Parkinson's disease model. Neurosci Lett 373(3), 189-94.

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