Faculty Associates

David J. Waters

Contact Information
Email: waters |at| purdue.edu
Office: LYNN 1296 Map
Phone: (765) 494-9271
Fax: (765) 775-1006
Homepage: Homepage
Associate Director, Center on Aging and the Life Course
Professor of Veterinary Clinical Sciences
Professor of Oncology, Veterinary Clinical Sciences
Director, Center for Exceptional Longevity Studies, Gerald P. Murphy Cancer Foundation

PubMed Listing
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Education


Ph.D. University of Minnesota 1992
DVM Cornell University 1984
B.S. Cornell University 1980

Research Interests


  • Aging - Cancer Connection
  • Comparative Aspects of Biogerontology
  • Sex Differences in Biology & Medicine
  • U-Shaped Dose Responses & Health Promotion
  • Pet Dogs as a Model for Human Healthspan
  • Personalized Cancer Prevention
  • Cancer Resistance in Centenarians

Teaching Interests


  • Biology of Aging
  • Lifestyle & Age-Related Disease in the News
  • Tocandtocs: Skills & Attitudes of Personal Performance
  • Endocrinology of Aging
  • Cancer and Aging
  • Gerontology Training for DVMs

Grants


American Cancer Society
Brookdale Foundation
Department of Defense Prostate Cancer Research Program
National Academies - Keck Foundation Initiative
National Institutes of Health

Awards and Honors


1997 - Consultant, National Cancer Institute Prostate Cancer Progress Review Group to Formulate the Prostate Cancer Research Agenda of the U.S.
1999 - Brookdale National Fellowship for Leadership in Gerontology and Geriatrics
2005 - Great Teacher Award for Exceptional Interdisciplinary Teaching, Purdue University - Center on Aging and the Life Course
2007 - Invited Scientist, Department of Defense Prostate Cancer Research Program IMPACT (Innovative Minds in Prostate Cancer Today) - Top researchers of the decade
2007 - Invited Scientist, National Academies of Sciences - Keck Future Initiatives: "The Future of Human Healthspan"
2009 - Award for Research in Biological Mechanisms of Aging, Glenn Foundation for Medical Research

Publications


Waters DJ, Patronek GJ, Bostwick DG, Glickman LT. Comparing the age at prostate cancer diagnosis in human and dogs. J Natl Cancer Inst 1996; 88: 1686-1687.

Patronek GJ, Waters DJ, Glickman LT. Comparative longevity of pet dogs and humans: implications for gerontology research. J Gerontol 1997; 52A: B171-B178.

Waters DJ, Shen S, Glickman LT. Life expectancy, antagonistic pleiotropy, and the testis of dogs and men. Prostate 2000; 43: 272-277.

Cooley DM, Schlittler DL, Glickman LT, Hayek M, Waters DJ. Exceptional longevity in pet dogs is accompanied by cancer resistance and delayed onset of major diseases. J Gerontol Biol Sci 2003; 58: B1078-1084.

Waters DJ, Shen S, Cooley DM, Bostwick DG, Qian J, Combs GF Jr, Glickman LT, Oteham C, Schlittler DL, Morris JS. Effects of dietary selenium supplementation on DNA damage and apoptosis in canine prostate. J Natl Cancer Inst 2003; 95: 237-241.

Bostwick DG, Burke HB, Djakiew D, Euling S, Ho SM, Landolph J, Morrison H, Sonawane B, Shifflett T, Waters DJ, Timms B. Human prostate cancer risk factors. Cancer 2004; 101(10 Suppl): 2371-2490.

Waters DJ, Chiang EC, Cooley DM, Morris JS. Making sense of sex and supplements: differences in the anticarcinogenic effects of selenium in men and women. Mutation Res 2004; 551: 91-107.

Waters DJ, Shen S, Glickman LT, Cooley DM, Bostwick DG, Qian J, Combs GF Jr, Morris JS. Prostate cancer risk and DNA damage: translational significance of selenium supplementation in a canine model. Carcinogenesis 2005; 26: 1256-1262.

Waters DJ, Wildasin K. Cancer clues from pet dogs. Scientific American 2006; 295: 94-101.

Waters DJ, Shen S, Xu H, Kengeri SS, Cooley DM, Chiang EC, Chen Y, Schlittler D, Oteham C, Combs GF Jr, Glickman LT, Morris JS, Bostwick DG. Noninvasive prediction of prostatic DNA damage by oxidative stress challenge of peripheral blood lymphocytes. Cancer Epidemiol Biomarkers Prev 2007; 16: 1906-1910.

Waters DJ, Chiang EC, Bostwick DG. The art of casting nets: fishing for the prize of personalized cancer prevention. Nutr Cancer 2008; 60: 1-6.

Rayman MP, Combs GF Jr, Waters DJ. Selenium and vitamin E supplementation for cancer prevention. JAMA 2009; 301: 1876.

Waters DJ, Kengeri SS, Clever B, Booth JA, Maras AH, Schlittler DL, Hayek MG. Exploring mechanisms of sex differences in longevity: lifetime ovary exposure and exceptional longevity in dogs. Aging Cell 2009; 8: 752-55.

Chiang EC, Shen S, Kengeri SS, Xu H, Combs GF Jr., Morris SJ, Bostwick DG, Waters DJ. Defining the optimal selenium dose for prostate cancer risk reduction: insights from the U-shaped relationship between selenium status, DNA damage, and apoptosis. Dose Response 2010; 8: 285-300.

Waters DJ. Aging research 2011: exploring the pet dog paradigm. ILAR Journal 2011; 52(1): 97-105.

Waters DJ, Waters LS. On the self-renewal of teachers. J Vet Med Educ 2011; 38(3): 235-241.

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