Faculty Associates

Wei Zheng

Contact Information
Email: wz18 |at| purdue.edu
Office: CIVL 1169A Map
Phone: (765) 496-6447
Fax: (765) 496-1377
Homepage: Homepage
Head, School of Health Sciences, College of Health and Human Sciences
Professor of Health Sciences and Toxicology

PubMed Listing
Google Scholar Listing

PDF icon View Vita

Education


M.S. Zhejiang University College of Pharmacy, Hangzhou, Pharmacology
Ph.D. University of Arizona, Tucson, AZ Pharmacology & Toxicology

Research Interests


Toxicology of blood-brain barrier and blood-CSF barrier. Neurotoxicology of heavy metals (lead, manganese, iron, aluminum, and mercury): transport, homeostasis in the CNS, and molecular mechanisms. Roles of brain barriers in etiology of neurodegenerative diseases such as Parkinson′s syndrome and Alzheimer′s disease. Chelation therapy of metal toxicities. Transport of substances by the blood-CSF barrier in the choroid plexus. In vitro model of blood-brain/CSF barrier.

Teaching Interests


HSCI 101 Introduction to the Health Sciences Professions

Grants


National Institutes of Health-National Institute of Environmental Health Sciences
National Institutes of Health-National Institute of Neurological Disorders and Stroke
U.S. Department of Defense

Publications


Li, H., Zhou, D. L., Zhang, Q., Feng, C. Y., Zheng, W., He, K. P., & Lan, Y. J. (2013). Vanadium exposure-induced neurobehavioral alterations among Chinese workers. Neurotoxicology, 36, 49-54.

Louis, E. D., Benito-León, J., Moreno-García, S., Vega, S., Romero, J. P., Bermejo-Pareja, F., Gerbin, M., Viner, A.S., Factor-Litvak, P., Jiang, W., & Zheng, W. (2013). Blood harmane (1-methyl-9h-pyrido[3,4-B]indole) concentration in essential tremor cases in Spain. Neurotoxicology, 34, 264-268.

Monnot, A. D., & Zheng, W. (2013). Culture of choroidal plexus epithelial cells and in vitro model of blood-CSF barrier. Methods in Molecular Biology (Epithelial Cell Culture Protocols) 945, 13-29.

Louis, E. D., Jiang, W., Gerbin, M., Viner, A. S., Factor-Litvak, P., & Zheng, W. (2012). Blood harmane (1-methyl-9h-pyrido[3,4-b]indole) concentrations in essential tremor: Repeat observation in cases and controls in New York. Journal of Toxicology and Environmental Health. Part A, 5, 673-683.

Monnot, A. D., Zheng, G., & Zheng, W. (2012). Mechanism of copper transport at the blood-cerebrospinal fluid barrier: Influence of iron deficiency. Experimental Biology and Medicine, 237, 327-333.

Park, J. D., & Zheng, W. (2012). Human exposure and health effects of inorganic and elemental mercury (Review). Journal of Preventive Medicine and Public Health, 45, 344-352.

Racette, B. A,, Aschner, M., Guilarte, T. R., Dydak, U., Criswell, S. R., & Zheng, W. (2012). Pathophysiology of manganese-associated neurotoxicity. Neurotoxicology ,33, 881-886.

Robison, G., Zakharova, T., Fu, X., Jiang, W., Fulper, R., Barrea, R., Marcus, M. A., Zheng, W., & Pushkar, Y. (2012). X-ray fluorescence imaging: A new tool for studying manganese neurotoxicity. PLoS ONE, 7(11), e48899.

Rutchik, J. S., Zheng, W., Jiang, Y. M., & Mo, X. E. (2012). How does an occupational neurologist assess welders and steelworkers for a manganese-induced movement disorder? An international team's experiences in Guangxi, China, Part II. Journal of Occupational and Environmental Medicine, 54(12), 1562-1564.

Rutchik, J. S., Zheng, W., Jiang, Y. M., & Mo, X. E. (2012). How does an occupational neurologist assess welders and steelworkers for a manganese-induced movement fisorder? An international team's experiences in Guangxi, China, Part I. Journal of Occupational and Environmental Medicine, 54(11), 1432-1434.

Zheng, G., Chen, J., & Zheng, W. (2012). Relative contribution of CTR1 and DMT1 in copper transport by the blood-CSF barrier: Implication in manganese neurotoxicity. Toxicology and Applied Pharmacology, 260, 285-293.

Zheng, W., & Monnot, A. D. (2012). Regulation of brain iron and copper homeostasis by brain barrier systems: Implication in neurodegenerative diseases. Pharmacology & Therapeutiacs, 133, 177-188.

Report a Problem