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Ralph W. and Grace M. Showalter Research Trust Award Recipients

2007

  • Ryan Cabot and Scott Briggs, animal sciences, biochemistry, $75,000, “Alterations in Chromatin Structure and Embryonic Origins of Disease.”
  • Stacey Mobley, Andy Tao and Laura Sands, foods and nutrition, biochemistry, nursing, $75,000, “Novel Proteomic Approaches for Early Detection of Metabolis Syndrome in Obese Adults.”
  • Chris Rochet and Tony Hazbun, medicinal chemistry & molecular pharmacology, $75,000, “DJ-1: An ‘On-switch’ for Cell Survival Pathways in the Brain.”
  • M. Teresa Carvajal and Masaru Rao, industrial & physical pharmacy, mechanical engineering, $74,820, “Microfabrication of Respirable Particles as an Alternative Approach to Formulation.”
  • Donna Fekete, Daniel Szeto, Zhao-Qing Luo, Paul Collodi and Kenneth Robinson, biological sciences, animal sciences, $40,000, “Zebrafish as a Model Organism for Development and Disease.”
  • Ourania Andrisani and Xiaoq Liu, basic medical sciences, biochemistry, $75,000, “Role of Polo-like Kinase (Plk1) in Liver Cancer Development Mediated by the Hepatitis B Virus X Protein.”
  • Susan Mendrysa and Tony R. Hazbun, basic medical sciences, medicinal chemistry and molecular pharmacy, $73,405, “Identification of Novel Anti- Cancer Drug Targets in Cells Overexpressing LYar.”
  • Mark Hall, Tony R. Hazbun and Harry Charbonneau, biochemistry, Bindley Bioscience Center, medicinal chemistry and molecular pharmacy, $60,000, “Cell Cycle Regulatory Functions of the 14-3-3 Protein Family.”
  • Kevin Gurney, Paul Shepson and Ahmed Elmagarmid, earth and atmospheric science, agronomy, computer science, Purdue Climate Control Research Center, $74,591, “The “Hestia” Project: Supporting Climate Science, Policy and Planning at Purdue.”


2006
  • Cheng, Ji-Xin and Shi, Riyi, Biomedical Engineering/Basic Medical Sciences, "Better Repair of Spinal Cord Injury with Polymer Micelle based Nanomedicine," $65,000
  • Donkin, Shawn and Teegarden, Dorothy, Animal Sciences/Foods and Nutrition, "Fetal Programming, Fructose, and Insulin Resistance," $65,000
  • Hockerman, Gregory H. and Watts, Val, Medicinal Chemistry and Molecular Pharmacology, "Potentiation of Insulin Secretion by GLP-1 Receptor Agonsits: Synergism and Forskolin and Potential Small Molecule Agonists," $75,000
  • Kane, Mike and Fleet, James and Donkin, Shawn, Computer and Information Technology/Foods and Nutrition/Animal Sciences, "Transcriptional Regulation Profiling of Genes Relevant to Prostate Cancer Progression," $73,581
  • LaCount, Douglas and Kuhn, Richard, Medicinal Chemistry and Molecular Pharmacology/Biological Sciences, "Identification of Human Protein Binding Partners of Dengue Virus Proteins," $75,000
  • Lipton, Mark and Chmielewski, Jean, Chemistry/Chemical Engineering, "Blocking Anthrax Toxin Interactions with Designed Agents," $65,000
  • Michalski, Greg and Niyogi, Devdutta and Joern, Brad, Earth and Atmospheric Sciences/Agronomy, "From Sources to Sinks - A Novel Isotopic Analysis of Nitrate Loading in Groundwater and Surface Runoff in Indiana Watersheds," $75,000
  • Mohammed, Sulma and Adamec, Jiri and Zhang, Xiang, Veterinary Pathobiology/Bindley Bioscience Center, "The Use of Proteomics to Determine Pathways of Metastasis," $65,000


2005
  • Hovis, Jennifer and Rochet, Jean-Christophe, Chemistry/Medicinal Chemistry & Molecular Pharmacology, “Understanding the Molecular Basis of Parkinson's Disease,” $75,000
  • Machaty, Zoltan and Bidwell, Christopher, Animal Sciences, “The Production of Adiponectin-Deficient Transgenic Pigs,” $75,000
  • Mittal, Suresh, Veterinary Pathobiology, “Enhancing Innate and Adaptive Immune Functions in Aging to Improve Vaccine Efficacy,” $75,000
  • Riese, David and Watts, Val, Medicinal Chemistry & Molecular Pharmacology, “Identification of a Potential Mechanism By Which Parkinson's Disease Patients Exhibit an Elevated Rick of Breast Cancer,” $75,000
  • Rochet, Jean-Christophe and Davisson, V. Jo, Medicinal Chemistry & Molecular Pharmacology, “A Link Between Oxidative Stress, Protein Aggregation, and Aging,” $75,000
  • Rundell, Ann, Biomedical Engineering, “Improved Resuscitation from Cardiac Arrest with Artificial Peripheral Resistance,” $25,000
  • Youngblood, Jeffrey and Applegate, Bruce, Materials Engineering/Food Science,” Hydrophilized Polymeric Bactericides for Medical Applications,” $75,000


2004
  • Camarillo, Ignacio and Mohammed, Sulma, Biological Sciences/Veterinary Pathobiology, “Analysis of Mammary Adipocyte gene Expression in an Obese Rat Model of Breast Cancer," $75,000
  • Engel, Bernard; Beyrouty, Craig; Lee, Linda; Mannering, Fred; and Govindaraju, Rao, Agricultural and Biological Engineering/Agronomy/Civil Engineering, "Fate and Transport of Livestock Antibiotics in Indiana Watersheds," $75,000
  • Feng, Zhilan, Mathematics, "Mathematical approaches for the study of control of emerging/re-emerging infectious diseases," $66,666
  • Fleet, James and Wu, Jing, Foods and Nutrition/Statistics, "Defining the Molecular Regulators Controlling the Development of a Functionally Mature Intestine," $75,000
  • Spurlock, Michael; Moody, Diane; and Hogenesch, Harm, Animal Sciences/Veterinary Pathobiology, "Development of a Porcine Model of the Human Metabolic Syndrome," $75,000
  • Webster, Thomas; Friedman, Alan; Fleet, James; Weaver, Connie; and Weatherman, Ross, Biomedical Engineering/Biological Sciences/Foods & Nutrition/Medicinal Chemistry and Molecular Pharmacology, "Development of Intelligent, Nanotechnology-based Materials for the Prevention and Treatment of Osteoporotic Bone," $66,666
  • Won, You-Yeon and Konieczny, Stephen Chemical Engineering/Biological Sciences, "A Novel Virus-Mimetic Approach for Gene Therapy," $66,666


2003
  • Anderson, John, Biological Sciences, "Synthesis and Characterization of a Novel Drug that Displays Specificity for the Human Immunodeficiency Virus (HIV) and Other Pathogens," $75,000
  • Andres, Ronald and Thompson, David, Chemical Engineering/Chemistry, "Development of Folic Acid Labeled Magnetic Nanoparticles for the MRI Identification and Hyperthermia Treatment of Cancer," $75,000
  • Bailey-Kellogg, Chris, Rothwell, Ian, and Laskowski, Michael, Computer Science/Chemistry, "Distribution Functions of Standard Free Energies of Protein-Protein Association," $74,800
  • Collodi, Paul, Animal Sciences, "Applications of Gene-Targeting Methods of Zebrafish," $72,500
  • Haberstroh, Karen, Biomedical Engineering, "The Use of Nano-Dimensional Bladder Tissue Replacement Constructs for the Treatment of Superficial Bladder Cancers," $75,000
  • Lee, Linda, Mannering, Fred, and Jafvert, Chad, Agronomy/Civil Engineering, "Occurrence and Fate of Emerging Organic Contaminants in Land-Applied Municipal Biosolids," $74,900.
  • Rundell, Ann and Forney, James, Biomedical Engineering/Biochemistry, "Development of a Cell Based Pathogen Detection Biosensor Exploiting the Selective Activation of Innate Immune Cells," $75,000


2002
  • Chen, Jue, Kuhn, Richard, and Rossmann, Michael, Biological Sciences, "Molecular Mechanism of Flavivirus Entry," $99,500
  • Golden, Barbara, Biochemistry, "Analysis of Virus Packaging Signals and Their Implications for Antiviral Drug Development," $100,000
  • Rao, P. Suresh; Jafvert, Chad; Hua, Inez; and Lee, Linda, Civil Engineering/Agronomy, "Innovative Technologies for Accelerated Groundwater Cleanup and Remediation Performance Assessment at Contaminated Sites," $99,952
  • Shepson, Paul and McMillin, David, Earth & Atmospheric Sciences/Chemistry, "Studies of the Impact of Atmospheric Nitrogen Deposition on the Sequestration of Carbon Dioxide by North American Forests," $100,000
  • Simpson, Garth, Chemistry, "Dielectrophoretic Force Microscopy for Ultrahigh Resolution Imaging in Solution," $100,000


2001
  • Amass, Sandra, Veterinary Clinical Sciences, "Animal Agroterrorism: Biosecurity Procedures for Emergency Responders," $83,000
  • Bidwell, Christopher; Aref, Walid; Doerge, Rebecca; McIntyre, Lauren; Moody, Diane; and Spurlock, Michael, Animal Sciences/Computer Science/Agronomy, "Functional Genomics for Animal Research," $83,000
  • Brouder, Sylvie and Turco, Ronald, Agronomy/Environmental Sciences & Engineering Institute [ESEI], "Functional Ecology of E. coli in the Indiana Landscape: Implications for Environmental Management and the Protection of Water Quality and Human Health," $83,000
  • Frankel, Steve; Haberstroh, Karen; Plesniak, Michael; Webster, Thomas; Wereley, Steve; and Xu, Lisa, Mechanical Engineering/Biomedical Engineering/, "Towards Prevention and Control of Atherosclererosis: Endothelial and Smooth Muscle Cell Response to Pulsatile Flow in Stemotic Blood Vessels," $83,000
  • Friedman, Alan; Lee, Gill; Taparowsky, Elizabeth; and Bashir, Rashid, Biological Sciences/Chemical Engineering/ Biomedical Engineering/Electrical & Computer Engineering, "Research Cluster for the Application of Synthetic DNA Analogues in Chemical Biology and Biotechnology," $83,000
  • McGough, Amy; Asai, David; Baker, Timothy; Kuhn, Richard; Rossmann, Michael; and Staiger, Christopher, Biological Sciences, "Cynamics of Biological Machines," $83,000
  • Morris, Kenneth, Industrial & Physical Pharmacy, "Dielectric Analysis Determination of the Rehydration Stability of Dehydration-Labile," $37,000
  • Wilker, Jonathan; Shi, Riyi; and Stroshine, Richard, Chemistry/Basic Medical Sciences/Agricultural & Biological Engineering, "Biological Adhesives for Surgical Applications," $83,000